PortalPublikationenEffective childhood cancer Treatment: the impact of large sc...

Effective childhood cancer Treatment: the impact of large scale clinical trials in Germany and Austria

Standard

Effective childhood cancer Treatment: the impact of large scale clinical trials in Germany and Austria. / Rossig, C; Juergens, H; Schrappe, M; Moericke, A; Henze, G; von Stackelberg, A; Reinhardt, D; Burkhardt, B; Woessmann, W; Zimmermann, M; Gadner, H; Mann, G; Schellong, G; Mauz-Koerholz, C; Dirksen, U; Bielack, S; Berthold, F; Graf, N; Rutkowski, S; Calaminus, G; Kaatsch, P; Creutzig, U.

in: PEDIATR BLOOD CANCER, Jahrgang 60, Nr. 10, 01.10.2013, S. 1574-81.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Rossig, C, Juergens, H, Schrappe, M, Moericke, A, Henze, G, von Stackelberg, A, Reinhardt, D, Burkhardt, B, Woessmann, W, Zimmermann, M, Gadner, H, Mann, G, Schellong, G, Mauz-Koerholz, C, Dirksen, U, Bielack, S, Berthold, F, Graf, N, Rutkowski, S, Calaminus, G, Kaatsch, P & Creutzig, U 2013, 'Effective childhood cancer Treatment: the impact of large scale clinical trials in Germany and Austria', PEDIATR BLOOD CANCER, Jg. 60, Nr. 10, S. 1574-81. https://doi.org/10.1002/pbc.24598

APA

Rossig, C., Juergens, H., Schrappe, M., Moericke, A., Henze, G., von Stackelberg, A., Reinhardt, D., Burkhardt, B., Woessmann, W., Zimmermann, M., Gadner, H., Mann, G., Schellong, G., Mauz-Koerholz, C., Dirksen, U., Bielack, S., Berthold, F., Graf, N., Rutkowski, S., ... Creutzig, U. (2013). Effective childhood cancer Treatment: the impact of large scale clinical trials in Germany and Austria. PEDIATR BLOOD CANCER, 60(10), 1574-81. https://doi.org/10.1002/pbc.24598

Vancouver

Rossig C, Juergens H, Schrappe M, Moericke A, Henze G, von Stackelberg A et al. Effective childhood cancer Treatment: the impact of large scale clinical trials in Germany and Austria. PEDIATR BLOOD CANCER. 2013 Okt 1;60(10):1574-81. https://doi.org/10.1002/pbc.24598

Bibtex

@article{9e319f0504934df397b5a388667cf072,
title = "Effective childhood cancer Treatment: the impact of large scale clinical trials in Germany and Austria",
abstract = "In Germany and Austria, more than 90% of pediatric cancer patients are enrolled into nationwide disease-specific first-line clinical trials or interim registries. Essential components are a pediatric cancer registry and centralized reference laboratories, imaging review, and tumor board assistance. The five-year overall survival rate in countries where such infrastructures are established has improved from <20% before 1950 to >80% since 1995. Today, treatment intensity is tailored to the individual patient's risk to provide the highest chances of survival while minimizing deleterious late effects. Multicenter clinical trials are internationalized and serve as platforms for further improvements by novel drugs and biologicals.",
keywords = "Adolescent, Austria, Child, Child, Preschool, Clinical Trials as Topic, Disease-Free Survival, Female, Germany, History, 20th Century, History, 21st Century, Humans, Infant, Male, Multicenter Studies as Topic, Neoplasms, Registries, Survival Rate",
author = "C Rossig and H Juergens and M Schrappe and A Moericke and G Henze and {von Stackelberg}, A and D Reinhardt and B Burkhardt and W Woessmann and M Zimmermann and H Gadner and G Mann and G Schellong and C Mauz-Koerholz and U Dirksen and S Bielack and F Berthold and N Graf and S Rutkowski and G Calaminus and P Kaatsch and U Creutzig",
note = "Copyright {\textcopyright} 2013 Wiley Periodicals, Inc.",
year = "2013",
month = oct,
day = "1",
doi = "10.1002/pbc.24598",
language = "English",
volume = "60",
pages = "1574--81",
journal = "PEDIATR BLOOD CANCER",
issn = "1545-5009",
publisher = "Wiley-Liss Inc.",
number = "10",

}

RIS

TY - JOUR

T1 - Effective childhood cancer Treatment: the impact of large scale clinical trials in Germany and Austria

AU - Rossig, C

AU - Juergens, H

AU - Schrappe, M

AU - Moericke, A

AU - Henze, G

AU - von Stackelberg, A

AU - Reinhardt, D

AU - Burkhardt, B

AU - Woessmann, W

AU - Zimmermann, M

AU - Gadner, H

AU - Mann, G

AU - Schellong, G

AU - Mauz-Koerholz, C

AU - Dirksen, U

AU - Bielack, S

AU - Berthold, F

AU - Graf, N

AU - Rutkowski, S

AU - Calaminus, G

AU - Kaatsch, P

AU - Creutzig, U

N1 - Copyright © 2013 Wiley Periodicals, Inc.

PY - 2013/10/1

Y1 - 2013/10/1

N2 - In Germany and Austria, more than 90% of pediatric cancer patients are enrolled into nationwide disease-specific first-line clinical trials or interim registries. Essential components are a pediatric cancer registry and centralized reference laboratories, imaging review, and tumor board assistance. The five-year overall survival rate in countries where such infrastructures are established has improved from <20% before 1950 to >80% since 1995. Today, treatment intensity is tailored to the individual patient's risk to provide the highest chances of survival while minimizing deleterious late effects. Multicenter clinical trials are internationalized and serve as platforms for further improvements by novel drugs and biologicals.

AB - In Germany and Austria, more than 90% of pediatric cancer patients are enrolled into nationwide disease-specific first-line clinical trials or interim registries. Essential components are a pediatric cancer registry and centralized reference laboratories, imaging review, and tumor board assistance. The five-year overall survival rate in countries where such infrastructures are established has improved from <20% before 1950 to >80% since 1995. Today, treatment intensity is tailored to the individual patient's risk to provide the highest chances of survival while minimizing deleterious late effects. Multicenter clinical trials are internationalized and serve as platforms for further improvements by novel drugs and biologicals.

KW - Adolescent

KW - Austria

KW - Child

KW - Child, Preschool

KW - Clinical Trials as Topic

KW - Disease-Free Survival

KW - Female

KW - Germany

KW - History, 20th Century

KW - History, 21st Century

KW - Humans

KW - Infant

KW - Male

KW - Multicenter Studies as Topic

KW - Neoplasms

KW - Registries

KW - Survival Rate

U2 - 10.1002/pbc.24598

DO - 10.1002/pbc.24598

M3 - SCORING: Journal article

C2 - 23737479

VL - 60

SP - 1574

EP - 1581

JO - PEDIATR BLOOD CANCER

JF - PEDIATR BLOOD CANCER

SN - 1545-5009

IS - 10

ER -