Duplexsonographische Untersuchungen zur retinalen Durchblutung nach Inhalation verschiedener Atemgasgemische

TY - JOUR

T1 - Duplexsonographische Untersuchungen zur retinalen Durchblutung nach Inhalation verschiedener Atemgasgemische

AU - Schüttauf, F

AU - Cobet, U

AU - Klemenz, A

AU - Krause, A

PY - 1998/4

Y1 - 1998/4

N2 - BACKGROUND: Hyperoxic-hypercapnic inhalation is a therapeutic option in vascular disorders of the retina. The effect of hyperoxic and/or hypercapnic inhalation on the perfusion of the retina was examined.METHODS: Twenty-five young adults between 18 and 35 years were investigated in a prospective study. They inhaled one of three different mixtures of breathing gases: (1) 100% O2, (2) Carbogen 240 (95% O2 and 5% CO2), (3) 92% O2 with 8% CO2 and were examined by color Doppler imaging of the CRA and OA before and after inhalation. The resistance index (RI) was calculated.RESULTS: The majority of the subjects showed an Increase in the RI in both ophthalmic vessels after inhalation of pure O2, a decrease after breathing in 92% O2 and 8% CO2 and it remained almost constant with inhalation of 95% O2 and 5% CO2.CONCLUSIONS: Inhalation of 92% O2 and 8% CO2 is a possibility for decreasing the peripheral resistance of OA and CRA. No change in blood flow was observed with Carbogen 240.

AB - BACKGROUND: Hyperoxic-hypercapnic inhalation is a therapeutic option in vascular disorders of the retina. The effect of hyperoxic and/or hypercapnic inhalation on the perfusion of the retina was examined.METHODS: Twenty-five young adults between 18 and 35 years were investigated in a prospective study. They inhaled one of three different mixtures of breathing gases: (1) 100% O2, (2) Carbogen 240 (95% O2 and 5% CO2), (3) 92% O2 with 8% CO2 and were examined by color Doppler imaging of the CRA and OA before and after inhalation. The resistance index (RI) was calculated.RESULTS: The majority of the subjects showed an Increase in the RI in both ophthalmic vessels after inhalation of pure O2, a decrease after breathing in 92% O2 and 8% CO2 and it remained almost constant with inhalation of 95% O2 and 5% CO2.CONCLUSIONS: Inhalation of 92% O2 and 8% CO2 is a possibility for decreasing the peripheral resistance of OA and CRA. No change in blood flow was observed with Carbogen 240.

KW - Adolescent

KW - Adult

KW - Blood Flow Velocity/drug effects

KW - Carbon Dioxide

KW - Female

KW - Humans

KW - Male

KW - Oxygen

KW - Oxygen Inhalation Therapy

KW - Prospective Studies

KW - Retinal Vessels/diagnostic imaging

KW - Ultrasonography, Doppler, Color

KW - Vascular Resistance/drug effects

U2 - 10.1007/s003470050266

DO - 10.1007/s003470050266

M3 - SCORING: Zeitschriftenaufsatz

C2 - 9623258

VL - 95

SP - 225

EP - 228

JO - OPHTHALMOLOGE

JF - OPHTHALMOLOGE

SN - 0941-293X

IS - 4

ER -