Duodenocolonic Fistula As A Rare Complication of Intestinal Burkitt Lymphoma in a Three-Year-Old Boy

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Duodenocolonic Fistula As A Rare Complication of Intestinal Burkitt Lymphoma in a Three-Year-Old Boy. / Okuda, Kenichi Vinzenz; Laass, Martin; Schuchardt, Katrin; Lange, Björn Sönke; Knöfler, Ralf; Fitze, Guido; Woessmann, Wilhelm; Suttorp, Meinolf.

in: KLIN PADIATR, Jahrgang 230, Nr. 3, 04.2018, S. 138-141.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

Harvard

Okuda, KV, Laass, M, Schuchardt, K, Lange, BS, Knöfler, R, Fitze, G, Woessmann, W & Suttorp, M 2018, 'Duodenocolonic Fistula As A Rare Complication of Intestinal Burkitt Lymphoma in a Three-Year-Old Boy', KLIN PADIATR, Jg. 230, Nr. 3, S. 138-141. https://doi.org/10.1055/a-0586-4045

APA

Okuda, K. V., Laass, M., Schuchardt, K., Lange, B. S., Knöfler, R., Fitze, G., Woessmann, W., & Suttorp, M. (2018). Duodenocolonic Fistula As A Rare Complication of Intestinal Burkitt Lymphoma in a Three-Year-Old Boy. KLIN PADIATR, 230(3), 138-141. https://doi.org/10.1055/a-0586-4045

Vancouver

Okuda KV, Laass M, Schuchardt K, Lange BS, Knöfler R, Fitze G et al. Duodenocolonic Fistula As A Rare Complication of Intestinal Burkitt Lymphoma in a Three-Year-Old Boy. KLIN PADIATR. 2018 Apr;230(3):138-141. https://doi.org/10.1055/a-0586-4045

Bibtex

@article{63dd31ff6a694a028c15f3667a665eed,
title = "Duodenocolonic Fistula As A Rare Complication of Intestinal Burkitt Lymphoma in a Three-Year-Old Boy",
abstract = "BACKGROUND: Burkitt lymphoma (BL) in children often presents with abdominal localization. Intestinal perforations have been described mainly during treatment. We report on a three-year-old patient with abdominal BL who was diagnosed with a duodenocolonic fistula.CASE REPORT: A three-year-old boy presented with diarrhea, crampy abdominal pain, and a four-week history of loss of appetite and weight. Ultrasound and MRI detected a colonic tumor forming a duodenocolonic fistula which was verified by gastroduodenoscopy. A surgical biopsy revealed BL. The stage III BL with low LDH was treated with four courses of BFM-type short-pulse chemotherapy. After two courses of chemotherapy the patient developed a mechanic ileus. A segmental resection of a short segment of the colon at the right flexure carrying the residual tumor mass with cicatricial stenosis and fistula followed by colonic end to end anastomosis and covering of the fistula by omentum major were carried out without complication. 15 days after surgery, two additional courses of chemotherapy could be administrated and the boy is in ongoing remission and free of any symptoms with a follow-up interval of 18 months.CONCLUSIONS: Duodeonocolonic fistula at presentation in a child with abdominal BL is extremely rare. Delayed surgery after size of the tumor bulk has been reduced by chemotherapy might represent a risk adapted approach. However, due to limited experience with duodenocolonic fistulas even in larger pediatric lymphoma trials any decision has to be based on the problems to be faced in individual cases.",
keywords = "Journal Article",
author = "Okuda, {Kenichi Vinzenz} and Martin Laass and Katrin Schuchardt and Lange, {Bj{\"o}rn S{\"o}nke} and Ralf Kn{\"o}fler and Guido Fitze and Wilhelm Woessmann and Meinolf Suttorp",
note = "{\textcopyright} Georg Thieme Verlag KG Stuttgart · New York.",
year = "2018",
month = apr,
doi = "10.1055/a-0586-4045",
language = "English",
volume = "230",
pages = "138--141",
journal = "KLIN PADIATR",
issn = "0300-8630",
publisher = "Georg Thieme Verlag KG",
number = "3",

}

RIS

TY - JOUR

T1 - Duodenocolonic Fistula As A Rare Complication of Intestinal Burkitt Lymphoma in a Three-Year-Old Boy

AU - Okuda, Kenichi Vinzenz

AU - Laass, Martin

AU - Schuchardt, Katrin

AU - Lange, Björn Sönke

AU - Knöfler, Ralf

AU - Fitze, Guido

AU - Woessmann, Wilhelm

AU - Suttorp, Meinolf

N1 - © Georg Thieme Verlag KG Stuttgart · New York.

PY - 2018/4

Y1 - 2018/4

N2 - BACKGROUND: Burkitt lymphoma (BL) in children often presents with abdominal localization. Intestinal perforations have been described mainly during treatment. We report on a three-year-old patient with abdominal BL who was diagnosed with a duodenocolonic fistula.CASE REPORT: A three-year-old boy presented with diarrhea, crampy abdominal pain, and a four-week history of loss of appetite and weight. Ultrasound and MRI detected a colonic tumor forming a duodenocolonic fistula which was verified by gastroduodenoscopy. A surgical biopsy revealed BL. The stage III BL with low LDH was treated with four courses of BFM-type short-pulse chemotherapy. After two courses of chemotherapy the patient developed a mechanic ileus. A segmental resection of a short segment of the colon at the right flexure carrying the residual tumor mass with cicatricial stenosis and fistula followed by colonic end to end anastomosis and covering of the fistula by omentum major were carried out without complication. 15 days after surgery, two additional courses of chemotherapy could be administrated and the boy is in ongoing remission and free of any symptoms with a follow-up interval of 18 months.CONCLUSIONS: Duodeonocolonic fistula at presentation in a child with abdominal BL is extremely rare. Delayed surgery after size of the tumor bulk has been reduced by chemotherapy might represent a risk adapted approach. However, due to limited experience with duodenocolonic fistulas even in larger pediatric lymphoma trials any decision has to be based on the problems to be faced in individual cases.

AB - BACKGROUND: Burkitt lymphoma (BL) in children often presents with abdominal localization. Intestinal perforations have been described mainly during treatment. We report on a three-year-old patient with abdominal BL who was diagnosed with a duodenocolonic fistula.CASE REPORT: A three-year-old boy presented with diarrhea, crampy abdominal pain, and a four-week history of loss of appetite and weight. Ultrasound and MRI detected a colonic tumor forming a duodenocolonic fistula which was verified by gastroduodenoscopy. A surgical biopsy revealed BL. The stage III BL with low LDH was treated with four courses of BFM-type short-pulse chemotherapy. After two courses of chemotherapy the patient developed a mechanic ileus. A segmental resection of a short segment of the colon at the right flexure carrying the residual tumor mass with cicatricial stenosis and fistula followed by colonic end to end anastomosis and covering of the fistula by omentum major were carried out without complication. 15 days after surgery, two additional courses of chemotherapy could be administrated and the boy is in ongoing remission and free of any symptoms with a follow-up interval of 18 months.CONCLUSIONS: Duodeonocolonic fistula at presentation in a child with abdominal BL is extremely rare. Delayed surgery after size of the tumor bulk has been reduced by chemotherapy might represent a risk adapted approach. However, due to limited experience with duodenocolonic fistulas even in larger pediatric lymphoma trials any decision has to be based on the problems to be faced in individual cases.

KW - Journal Article

U2 - 10.1055/a-0586-4045

DO - 10.1055/a-0586-4045

M3 - SCORING: Journal article

C2 - 29618138

VL - 230

SP - 138

EP - 141

JO - KLIN PADIATR

JF - KLIN PADIATR

SN - 0300-8630

IS - 3

ER -