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Drug dosing and monitoring in obese patients undergoing allogenic stem cell transplantation.

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Drug dosing and monitoring in obese patients undergoing allogenic stem cell transplantation. / Langebrake, Claudia; Bernhardt, Friederike; Baehr, Michael; Kröger, Nicolaus; Zander, Axel R.

in: INT J CLIN PHARM-NET, Jahrgang 33, Nr. 6, 6, 2011, S. 918-924.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Langebrake, C, Bernhardt, F, Baehr, M, Kröger, N & Zander, AR 2011, 'Drug dosing and monitoring in obese patients undergoing allogenic stem cell transplantation.', INT J CLIN PHARM-NET, Jg. 33, Nr. 6, 6, S. 918-924. <http://www.ncbi.nlm.nih.gov/pubmed/21960151?dopt=Citation>

APA

Langebrake, C., Bernhardt, F., Baehr, M., Kröger, N., & Zander, A. R. (2011). Drug dosing and monitoring in obese patients undergoing allogenic stem cell transplantation. INT J CLIN PHARM-NET, 33(6), 918-924. [6]. http://www.ncbi.nlm.nih.gov/pubmed/21960151?dopt=Citation

Vancouver

Langebrake C, Bernhardt F, Baehr M, Kröger N, Zander AR. Drug dosing and monitoring in obese patients undergoing allogenic stem cell transplantation. INT J CLIN PHARM-NET. 2011;33(6):918-924. 6.

Bibtex

@article{d895ca51969a44d0b5671505142de3be,
title = "Drug dosing and monitoring in obese patients undergoing allogenic stem cell transplantation.",
abstract = "The effects of physiological changes in patients with obesity on pharmacokinetic parameters and the time course of drug response, especially in the field of haematology/oncology, are poorly understood. For some antimicrobial drugs, dosing considerations exist, while for cytostatic drugs, dose modifications for obese patients are not consistently recommended. Glomerular filtration rate and renal perfusion appear to be similar in obese and normal weight individuals, thus elimination of hydrophilic and extensively renally cleared drugs mainly depends upon creatinine clearance.",
author = "Claudia Langebrake and Friederike Bernhardt and Michael Baehr and Nicolaus Kr{\"o}ger and Zander, {Axel R.}",
year = "2011",
language = "English",
volume = "33",
pages = "918--924",
journal = "INT J CLIN PHARM-NET",
issn = "2210-7703",
publisher = "Springer Netherlands",
number = "6",

}

RIS

TY - JOUR

T1 - Drug dosing and monitoring in obese patients undergoing allogenic stem cell transplantation.

AU - Langebrake, Claudia

AU - Bernhardt, Friederike

AU - Baehr, Michael

AU - Kröger, Nicolaus

AU - Zander, Axel R.

PY - 2011

Y1 - 2011

N2 - The effects of physiological changes in patients with obesity on pharmacokinetic parameters and the time course of drug response, especially in the field of haematology/oncology, are poorly understood. For some antimicrobial drugs, dosing considerations exist, while for cytostatic drugs, dose modifications for obese patients are not consistently recommended. Glomerular filtration rate and renal perfusion appear to be similar in obese and normal weight individuals, thus elimination of hydrophilic and extensively renally cleared drugs mainly depends upon creatinine clearance.

AB - The effects of physiological changes in patients with obesity on pharmacokinetic parameters and the time course of drug response, especially in the field of haematology/oncology, are poorly understood. For some antimicrobial drugs, dosing considerations exist, while for cytostatic drugs, dose modifications for obese patients are not consistently recommended. Glomerular filtration rate and renal perfusion appear to be similar in obese and normal weight individuals, thus elimination of hydrophilic and extensively renally cleared drugs mainly depends upon creatinine clearance.

M3 - SCORING: Journal article

VL - 33

SP - 918

EP - 924

JO - INT J CLIN PHARM-NET

JF - INT J CLIN PHARM-NET

SN - 2210-7703

IS - 6

M1 - 6

ER -