'Drip-and-drive': shipping the neurointerventionalist to provide mechanical thrombectomy in primary stroke centers

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'Drip-and-drive': shipping the neurointerventionalist to provide mechanical thrombectomy in primary stroke centers. / Brekenfeld, Caspar; Goebell, Einar; Schmidt, Holger; Henningsen, Henning; Kraemer, Christoffer; Tebben, Jörg; Flottmann, Fabian; Thomalla, Götz; Fiehler, Jens.

in: J NEUROINTERV SURG, Jahrgang 10, Nr. 10, 10.2018, S. 932-936.

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@article{2d9a6606dcc748cd8e4c7bd8553a2f16,
title = "'Drip-and-drive': shipping the neurointerventionalist to provide mechanical thrombectomy in primary stroke centers",
abstract = "BACKGROUND: To satisfy the increasing demand of mechanical thrombectomy (MT) for acute ischemic stroke treatment, new organizational concepts for patient care are required. This study evaluates time intervals of acute stroke management in two stroke care models, including one based on transportation of the interventionalist from a comprehensive stroke center (CSC) to treat patients in two primary stroke centers (PSC). We hypothesized that time intervals were not inferior for the 'drip-and-drive' concept compared with the traditional 'drip-and-ship' concept.METHODS: Patients treated with MT at the PSC ('drip-and-drive', 'D+D group') were compared with patients transferred from PSC to CSC for MT ('drip-and-ship', 'D+S group') with regard to time delays. Time intervals assessed were: symptom onset to initial CT, to angiography, and to recanalization; time from initial CT to telephone call activation, to arrival, and to angiography; and time from telephone call activation to arrival and from arrival to angiography.RESULTS: 42 patients were treated at the PSC after transfer of the interventionalist, and 32 patients were transferred to the CSC for MT. The groups did not differ with regard to median Onset-CT and CT-Phone times. Significant differences between the groups were found for the primary outcome measure CT-Arrival time ('D+D group': median 121 (IQR 108-134) min vs 181 (157-219) min for the 'D+S group'; P<0.001). Time difference between the groups increased to more than 2 hours for median CT-Angio times (median 123 (IQR 93-147) min vs 252 (228-275) min; P<0.001).CONCLUSION: Time intervals for the 'D+D group' were not inferior to those of the 'D+S group'. Moreover, under certain conditions, the 'drip-and-drive' concept might even be superior.",
keywords = "Aged, Aged, 80 and over, Brain Ischemia, Female, Hospitals, Humans, Male, Middle Aged, Neurosurgeons, Patient Transfer, Stroke, Thrombectomy, Treatment Outcome, Journal Article, Multicenter Study",
author = "Caspar Brekenfeld and Einar Goebell and Holger Schmidt and Henning Henningsen and Christoffer Kraemer and J{\"o}rg Tebben and Fabian Flottmann and G{\"o}tz Thomalla and Jens Fiehler",
note = "{\textcopyright} Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.",
year = "2018",
month = oct,
doi = "10.1136/neurintsurg-2017-013634",
language = "English",
volume = "10",
pages = "932--936",
journal = "J NEUROINTERV SURG",
issn = "1759-8478",
publisher = "BMJ PUBLISHING GROUP",
number = "10",

}

RIS

TY - JOUR

T1 - 'Drip-and-drive': shipping the neurointerventionalist to provide mechanical thrombectomy in primary stroke centers

AU - Brekenfeld, Caspar

AU - Goebell, Einar

AU - Schmidt, Holger

AU - Henningsen, Henning

AU - Kraemer, Christoffer

AU - Tebben, Jörg

AU - Flottmann, Fabian

AU - Thomalla, Götz

AU - Fiehler, Jens

N1 - © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

PY - 2018/10

Y1 - 2018/10

N2 - BACKGROUND: To satisfy the increasing demand of mechanical thrombectomy (MT) for acute ischemic stroke treatment, new organizational concepts for patient care are required. This study evaluates time intervals of acute stroke management in two stroke care models, including one based on transportation of the interventionalist from a comprehensive stroke center (CSC) to treat patients in two primary stroke centers (PSC). We hypothesized that time intervals were not inferior for the 'drip-and-drive' concept compared with the traditional 'drip-and-ship' concept.METHODS: Patients treated with MT at the PSC ('drip-and-drive', 'D+D group') were compared with patients transferred from PSC to CSC for MT ('drip-and-ship', 'D+S group') with regard to time delays. Time intervals assessed were: symptom onset to initial CT, to angiography, and to recanalization; time from initial CT to telephone call activation, to arrival, and to angiography; and time from telephone call activation to arrival and from arrival to angiography.RESULTS: 42 patients were treated at the PSC after transfer of the interventionalist, and 32 patients were transferred to the CSC for MT. The groups did not differ with regard to median Onset-CT and CT-Phone times. Significant differences between the groups were found for the primary outcome measure CT-Arrival time ('D+D group': median 121 (IQR 108-134) min vs 181 (157-219) min for the 'D+S group'; P<0.001). Time difference between the groups increased to more than 2 hours for median CT-Angio times (median 123 (IQR 93-147) min vs 252 (228-275) min; P<0.001).CONCLUSION: Time intervals for the 'D+D group' were not inferior to those of the 'D+S group'. Moreover, under certain conditions, the 'drip-and-drive' concept might even be superior.

AB - BACKGROUND: To satisfy the increasing demand of mechanical thrombectomy (MT) for acute ischemic stroke treatment, new organizational concepts for patient care are required. This study evaluates time intervals of acute stroke management in two stroke care models, including one based on transportation of the interventionalist from a comprehensive stroke center (CSC) to treat patients in two primary stroke centers (PSC). We hypothesized that time intervals were not inferior for the 'drip-and-drive' concept compared with the traditional 'drip-and-ship' concept.METHODS: Patients treated with MT at the PSC ('drip-and-drive', 'D+D group') were compared with patients transferred from PSC to CSC for MT ('drip-and-ship', 'D+S group') with regard to time delays. Time intervals assessed were: symptom onset to initial CT, to angiography, and to recanalization; time from initial CT to telephone call activation, to arrival, and to angiography; and time from telephone call activation to arrival and from arrival to angiography.RESULTS: 42 patients were treated at the PSC after transfer of the interventionalist, and 32 patients were transferred to the CSC for MT. The groups did not differ with regard to median Onset-CT and CT-Phone times. Significant differences between the groups were found for the primary outcome measure CT-Arrival time ('D+D group': median 121 (IQR 108-134) min vs 181 (157-219) min for the 'D+S group'; P<0.001). Time difference between the groups increased to more than 2 hours for median CT-Angio times (median 123 (IQR 93-147) min vs 252 (228-275) min; P<0.001).CONCLUSION: Time intervals for the 'D+D group' were not inferior to those of the 'D+S group'. Moreover, under certain conditions, the 'drip-and-drive' concept might even be superior.

KW - Aged

KW - Aged, 80 and over

KW - Brain Ischemia

KW - Female

KW - Hospitals

KW - Humans

KW - Male

KW - Middle Aged

KW - Neurosurgeons

KW - Patient Transfer

KW - Stroke

KW - Thrombectomy

KW - Treatment Outcome

KW - Journal Article

KW - Multicenter Study

U2 - 10.1136/neurintsurg-2017-013634

DO - 10.1136/neurintsurg-2017-013634

M3 - SCORING: Journal article

C2 - 29436505

VL - 10

SP - 932

EP - 936

JO - J NEUROINTERV SURG

JF - J NEUROINTERV SURG

SN - 1759-8478

IS - 10

ER -