Distribution of Merkel cells in acute UVB erythema.
Standard
Distribution of Merkel cells in acute UVB erythema. / Moll, Ingrid; Bladt, U; Jung, E G.
in: ARCH DERMATOL RES, Jahrgang 284, Nr. 5, 5, 1992, S. 271-274.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Distribution of Merkel cells in acute UVB erythema.
AU - Moll, Ingrid
AU - Bladt, U
AU - Jung, E G
PY - 1992
Y1 - 1992
N2 - Merkel cells (MC) were identified immunohistochemically using antibodies specific for cytokeratin (CK) 20 within human epidermis 12 to 72 h after exposure to UVB (4 MED). 12 h after exposure all MC were normally localized within the epidermal basal layer. However, 24 h after exposure 4% of the MC were detected suprabasally, the remaining 96% still being situated in the basal layer. Surprisingly, at 48 h and 72 h more than 50% had lost contact with the basal membrane. The MC of hair follicles did not show any obvious changes. These results argue, in the context of acute epidermal UV damage, for an abnormal turnover in dermatitis.
AB - Merkel cells (MC) were identified immunohistochemically using antibodies specific for cytokeratin (CK) 20 within human epidermis 12 to 72 h after exposure to UVB (4 MED). 12 h after exposure all MC were normally localized within the epidermal basal layer. However, 24 h after exposure 4% of the MC were detected suprabasally, the remaining 96% still being situated in the basal layer. Surprisingly, at 48 h and 72 h more than 50% had lost contact with the basal membrane. The MC of hair follicles did not show any obvious changes. These results argue, in the context of acute epidermal UV damage, for an abnormal turnover in dermatitis.
M3 - SCORING: Zeitschriftenaufsatz
VL - 284
SP - 271
EP - 274
JO - ARCH DERMATOL RES
JF - ARCH DERMATOL RES
SN - 0340-3696
IS - 5
M1 - 5
ER -
