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Dimethylarginines: their vascular and metabolic roles in Africans and Caucasians.

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Dimethylarginines: their vascular and metabolic roles in Africans and Caucasians. / Schutte, Aletta; Schutte, Rudolph; Huisman, Hugo; Johannes, Van Rooyen; Fourie, Carla; Malan, Leone; Malan, Nico; Schwedhelm, Edzard; Strimbeanu, Sebastian; Anderssohn, Maike; Böger, Rainer.

in: EUR J ENDOCRINOL, Jahrgang 162, Nr. 3, 3, 2010, S. 525-533.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Schutte, A, Schutte, R, Huisman, H, Johannes, VR, Fourie, C, Malan, L, Malan, N, Schwedhelm, E, Strimbeanu, S, Anderssohn, M & Böger, R 2010, 'Dimethylarginines: their vascular and metabolic roles in Africans and Caucasians.', EUR J ENDOCRINOL, Jg. 162, Nr. 3, 3, S. 525-533. <http://www.ncbi.nlm.nih.gov/pubmed/19996198?dopt=Citation>

APA

Schutte, A., Schutte, R., Huisman, H., Johannes, V. R., Fourie, C., Malan, L., Malan, N., Schwedhelm, E., Strimbeanu, S., Anderssohn, M., & Böger, R. (2010). Dimethylarginines: their vascular and metabolic roles in Africans and Caucasians. EUR J ENDOCRINOL, 162(3), 525-533. [3]. http://www.ncbi.nlm.nih.gov/pubmed/19996198?dopt=Citation

Vancouver

Schutte A, Schutte R, Huisman H, Johannes VR, Fourie C, Malan L et al. Dimethylarginines: their vascular and metabolic roles in Africans and Caucasians. EUR J ENDOCRINOL. 2010;162(3):525-533. 3.

Bibtex

@article{288c4754cc3c4036b2a6cd06615fa6d7,
title = "Dimethylarginines: their vascular and metabolic roles in Africans and Caucasians.",
abstract = "Objective: Alarming increases in hypertension and type 2 diabetes among Africans accentuate the need to identify factors that could serve as targets for prevention or treatment. In Caucasian populations asymmetric dimethylarginine (ADMA), the predominant endogenous nitric oxide synthase inhibitor, is associated with cardiovascular disease and insulin resistance. ADMA's counterpart, symmetric dimethylarginine (SDMA), originally thought to be inert, was recently also linked with cardiovascular risk. Since little information regarding ADMA or SDMA is available for Africans, our aim was to explore the relationships of ADMA and SDMA with measures of arterial stiffness and insulin resistance in Africans and Caucasians from South Africa. Methods: The study consisted of 235 non-smoking, non-diabetic, non-obese, HIV uninfected Africans (N=64) and Caucasians (N=171), aged 20-70 years. We measured blood pressure, pulse wave velocity (PWV), ADMA, SDMA, and insulin resistance (HOMA). Results: African and Caucasian men had similar ADMA and SDMA, whereas Caucasian women had higher ADMA and SDMA than African women (p",
author = "Aletta Schutte and Rudolph Schutte and Hugo Huisman and Johannes, {Van Rooyen} and Carla Fourie and Leone Malan and Nico Malan and Edzard Schwedhelm and Sebastian Strimbeanu and Maike Anderssohn and Rainer B{\"o}ger",
year = "2010",
language = "Deutsch",
volume = "162",
pages = "525--533",
journal = "EUR J ENDOCRINOL",
issn = "0804-4643",
publisher = "BioScientifica Ltd.",
number = "3",

}

RIS

TY - JOUR

T1 - Dimethylarginines: their vascular and metabolic roles in Africans and Caucasians.

AU - Schutte, Aletta

AU - Schutte, Rudolph

AU - Huisman, Hugo

AU - Johannes, Van Rooyen

AU - Fourie, Carla

AU - Malan, Leone

AU - Malan, Nico

AU - Schwedhelm, Edzard

AU - Strimbeanu, Sebastian

AU - Anderssohn, Maike

AU - Böger, Rainer

PY - 2010

Y1 - 2010

N2 - Objective: Alarming increases in hypertension and type 2 diabetes among Africans accentuate the need to identify factors that could serve as targets for prevention or treatment. In Caucasian populations asymmetric dimethylarginine (ADMA), the predominant endogenous nitric oxide synthase inhibitor, is associated with cardiovascular disease and insulin resistance. ADMA's counterpart, symmetric dimethylarginine (SDMA), originally thought to be inert, was recently also linked with cardiovascular risk. Since little information regarding ADMA or SDMA is available for Africans, our aim was to explore the relationships of ADMA and SDMA with measures of arterial stiffness and insulin resistance in Africans and Caucasians from South Africa. Methods: The study consisted of 235 non-smoking, non-diabetic, non-obese, HIV uninfected Africans (N=64) and Caucasians (N=171), aged 20-70 years. We measured blood pressure, pulse wave velocity (PWV), ADMA, SDMA, and insulin resistance (HOMA). Results: African and Caucasian men had similar ADMA and SDMA, whereas Caucasian women had higher ADMA and SDMA than African women (p

AB - Objective: Alarming increases in hypertension and type 2 diabetes among Africans accentuate the need to identify factors that could serve as targets for prevention or treatment. In Caucasian populations asymmetric dimethylarginine (ADMA), the predominant endogenous nitric oxide synthase inhibitor, is associated with cardiovascular disease and insulin resistance. ADMA's counterpart, symmetric dimethylarginine (SDMA), originally thought to be inert, was recently also linked with cardiovascular risk. Since little information regarding ADMA or SDMA is available for Africans, our aim was to explore the relationships of ADMA and SDMA with measures of arterial stiffness and insulin resistance in Africans and Caucasians from South Africa. Methods: The study consisted of 235 non-smoking, non-diabetic, non-obese, HIV uninfected Africans (N=64) and Caucasians (N=171), aged 20-70 years. We measured blood pressure, pulse wave velocity (PWV), ADMA, SDMA, and insulin resistance (HOMA). Results: African and Caucasian men had similar ADMA and SDMA, whereas Caucasian women had higher ADMA and SDMA than African women (p

M3 - SCORING: Zeitschriftenaufsatz

VL - 162

SP - 525

EP - 533

JO - EUR J ENDOCRINOL

JF - EUR J ENDOCRINOL

SN - 0804-4643

IS - 3

M1 - 3

ER -