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Dietary and metabolic modulators of hepatic immunity

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Dietary and metabolic modulators of hepatic immunity. / Carambia, Antonella; Herkel, Johannes.

in: SEMIN IMMUNOPATHOL, Jahrgang 40, Nr. 2, 15.02.2018, S. 175 - 188.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung

Harvard

Carambia, A & Herkel, J 2018, 'Dietary and metabolic modulators of hepatic immunity', SEMIN IMMUNOPATHOL, Jg. 40, Nr. 2, S. 175 - 188.

APA

Carambia, A., & Herkel, J. (2018). Dietary and metabolic modulators of hepatic immunity. SEMIN IMMUNOPATHOL, 40(2), 175 - 188.

Vancouver

Carambia A, Herkel J. Dietary and metabolic modulators of hepatic immunity. SEMIN IMMUNOPATHOL. 2018 Feb 15;40(2):175 - 188.

Bibtex

@article{e25f7ed2fc0f4bc98f56c0a975875662,
title = "Dietary and metabolic modulators of hepatic immunity",
abstract = "The liver is the central metabolic organ of the organism and is thus constantly exposed to gut-derived dietary and microbial antigens. The liver maintains homoeostatic tolerance to these mostly harmless antigens. However, the liver also functions as a barrier organ to harmful pathogens and is thus permissive to liver inflammation. The regulation of the delicate balance between liver tolerance and liver inflammation is of vital importance for the organism. In recent years, a general role for dietary components and metabolites as immune mediators has been emerging. However, although the liver is exposed to a great deal of metabolic mediators, surprisingly, little is known about their actual role in the regulation of hepatic immune responses. Here, we will explore the possible impacts of metabolic mediators for homoeostatic and pathological immunity in the liver, by highlighting selected examples of metabolic immune regulation in the liver.",
author = "Antonella Carambia and Johannes Herkel",
year = "2018",
month = feb,
day = "15",
language = "English",
volume = "40",
pages = "175 -- 188",
journal = "SEMIN IMMUNOPATHOL",
issn = "1863-2297",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Dietary and metabolic modulators of hepatic immunity

AU - Carambia, Antonella

AU - Herkel, Johannes

PY - 2018/2/15

Y1 - 2018/2/15

N2 - The liver is the central metabolic organ of the organism and is thus constantly exposed to gut-derived dietary and microbial antigens. The liver maintains homoeostatic tolerance to these mostly harmless antigens. However, the liver also functions as a barrier organ to harmful pathogens and is thus permissive to liver inflammation. The regulation of the delicate balance between liver tolerance and liver inflammation is of vital importance for the organism. In recent years, a general role for dietary components and metabolites as immune mediators has been emerging. However, although the liver is exposed to a great deal of metabolic mediators, surprisingly, little is known about their actual role in the regulation of hepatic immune responses. Here, we will explore the possible impacts of metabolic mediators for homoeostatic and pathological immunity in the liver, by highlighting selected examples of metabolic immune regulation in the liver.

AB - The liver is the central metabolic organ of the organism and is thus constantly exposed to gut-derived dietary and microbial antigens. The liver maintains homoeostatic tolerance to these mostly harmless antigens. However, the liver also functions as a barrier organ to harmful pathogens and is thus permissive to liver inflammation. The regulation of the delicate balance between liver tolerance and liver inflammation is of vital importance for the organism. In recent years, a general role for dietary components and metabolites as immune mediators has been emerging. However, although the liver is exposed to a great deal of metabolic mediators, surprisingly, little is known about their actual role in the regulation of hepatic immune responses. Here, we will explore the possible impacts of metabolic mediators for homoeostatic and pathological immunity in the liver, by highlighting selected examples of metabolic immune regulation in the liver.

M3 - SCORING: Review article

VL - 40

SP - 175

EP - 188

JO - SEMIN IMMUNOPATHOL

JF - SEMIN IMMUNOPATHOL

SN - 1863-2297

IS - 2

ER -