Diagnostik und Therapie von Tuberkulose unter Immuntherapien für Multiple Sklerose: Aktueller Stand und Empfehlungen in Deutschland
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Diagnostik und Therapie von Tuberkulose unter Immuntherapien für Multiple Sklerose: Aktueller Stand und Empfehlungen in Deutschland. / Bittner, Stefan; Engel, Sinah; Lange, Christoph; Weber, Martin S; Haghikia, Aiden; Luessi, Felix; Korn, Thomas; Klotz, Luisa; Bayas, Antonios; Paul, Friedemann; Heesen, Christoph; Stangel, Martin; Wildemann, Brigitte; Bergh, Florian Then; Tackenberg, Björn; Trebst, Corinna; Warnke, Clemens; Linker, Ralf; Kerschensteiner, Martin; Zettl, Uwe; Tumani, Hayrettin; Brück, Wolfgang; Meuth, Sven G; Kümpfel, Tanja; Hemmer, Bernhard; Wiendl, Heinz; Gold, Ralf; Zipp, Frauke.
in: NERVENARZT, Jahrgang 90, Nr. 12, 12.2019, S. 1245-1253.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung
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TY - JOUR
T1 - Diagnostik und Therapie von Tuberkulose unter Immuntherapien für Multiple Sklerose: Aktueller Stand und Empfehlungen in Deutschland
AU - Bittner, Stefan
AU - Engel, Sinah
AU - Lange, Christoph
AU - Weber, Martin S
AU - Haghikia, Aiden
AU - Luessi, Felix
AU - Korn, Thomas
AU - Klotz, Luisa
AU - Bayas, Antonios
AU - Paul, Friedemann
AU - Heesen, Christoph
AU - Stangel, Martin
AU - Wildemann, Brigitte
AU - Bergh, Florian Then
AU - Tackenberg, Björn
AU - Trebst, Corinna
AU - Warnke, Clemens
AU - Linker, Ralf
AU - Kerschensteiner, Martin
AU - Zettl, Uwe
AU - Tumani, Hayrettin
AU - Brück, Wolfgang
AU - Meuth, Sven G
AU - Kümpfel, Tanja
AU - Hemmer, Bernhard
AU - Wiendl, Heinz
AU - Gold, Ralf
AU - Zipp, Frauke
PY - 2019/12
Y1 - 2019/12
N2 - After years of low incidence, a large increase of new tuberculosis (TB) cases has been reported in Germany since 2015. New immunotherapies for the treatment of multiple sclerosis (MS) are associated with a reduced immune competence and a potential increased risk for infections. Most neurologists lack specific experiences with TB infections. This article summarizes specific recommendations for the diagnostics and treatment of TB under MS immunotherapies with a focus on the situation in Germany. Due to low case numbers and little experience with the risk of TB under the new immunotherapies, the clinical competence network for MS (KKNMS) consensus recommendations have a low grade of evidence.
AB - After years of low incidence, a large increase of new tuberculosis (TB) cases has been reported in Germany since 2015. New immunotherapies for the treatment of multiple sclerosis (MS) are associated with a reduced immune competence and a potential increased risk for infections. Most neurologists lack specific experiences with TB infections. This article summarizes specific recommendations for the diagnostics and treatment of TB under MS immunotherapies with a focus on the situation in Germany. Due to low case numbers and little experience with the risk of TB under the new immunotherapies, the clinical competence network for MS (KKNMS) consensus recommendations have a low grade of evidence.
U2 - 10.1007/s00115-019-0760-0
DO - 10.1007/s00115-019-0760-0
M3 - SCORING: Review
C2 - 31297574
VL - 90
SP - 1245
EP - 1253
JO - NERVENARZT
JF - NERVENARZT
SN - 0028-2804
IS - 12
ER -