Diagnostic value of PSA and AP tests for the detection of spermatozoa in postmortem swabs from the genital and anal region in males

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Diagnostic value of PSA and AP tests for the detection of spermatozoa in postmortem swabs from the genital and anal region in males. / Weitzig, Laurence ; Schroeder, Ann Sophie; Augustin, Christa; Raupach, Tobias; Sehner, Susanne; Anders, Sven.

in: J FORENSIC SCI, Jahrgang 60, Nr. 1, 01.2015, S. 41-4.

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@article{1deec13fb2674adca40e1fb19df8c30b,
title = "Diagnostic value of PSA and AP tests for the detection of spermatozoa in postmortem swabs from the genital and anal region in males",
abstract = "The aim of this study was to clarify whether positive results for prostate-specific antigen (PSA) and acid phosphatase (AP) occur in postmortem swabs from the genito-anal region in males (n = 80; 4 regions) and females (n = 20; 3 regions) and to calculate the positive predictive value (PPV) concerning the presence of spermatozoa. In male subjects, the highest incidence of positive test results was found in urethral swabs (PSA 76%, AP 71%) and the lowest frequencies appeared in perianal and rectal swabs (15-20%). Microscopic evaluation for spermatozoa was positive between 39% in urethral swabs and 1% in rectal swabs. PPV regarding positive identification of spermatozoa was 33.3% for PSA and 31.5% for AP. The combination of both tests yielded a PPV of 38.2%. In female cases, no spermatozoa were identified, and one case was PSA- and AP-positive in perianal swabs. Our findings indicate that PSA and AP tests are of limited value for the postmortem detection of spermatozoa in male subjects.",
author = "Laurence Weitzig and Schroeder, {Ann Sophie} and Christa Augustin and Tobias Raupach and Susanne Sehner and Sven Anders",
note = "{\textcopyright} 2014 American Academy of Forensic Sciences.",
year = "2015",
month = jan,
doi = "10.1111/1556-4029.12632",
language = "English",
volume = "60",
pages = "41--4",
journal = "J FORENSIC SCI",
issn = "0022-1198",
publisher = "Wiley-Blackwell",
number = "1",

}

RIS

TY - JOUR

T1 - Diagnostic value of PSA and AP tests for the detection of spermatozoa in postmortem swabs from the genital and anal region in males

AU - Weitzig, Laurence

AU - Schroeder, Ann Sophie

AU - Augustin, Christa

AU - Raupach, Tobias

AU - Sehner, Susanne

AU - Anders, Sven

N1 - © 2014 American Academy of Forensic Sciences.

PY - 2015/1

Y1 - 2015/1

N2 - The aim of this study was to clarify whether positive results for prostate-specific antigen (PSA) and acid phosphatase (AP) occur in postmortem swabs from the genito-anal region in males (n = 80; 4 regions) and females (n = 20; 3 regions) and to calculate the positive predictive value (PPV) concerning the presence of spermatozoa. In male subjects, the highest incidence of positive test results was found in urethral swabs (PSA 76%, AP 71%) and the lowest frequencies appeared in perianal and rectal swabs (15-20%). Microscopic evaluation for spermatozoa was positive between 39% in urethral swabs and 1% in rectal swabs. PPV regarding positive identification of spermatozoa was 33.3% for PSA and 31.5% for AP. The combination of both tests yielded a PPV of 38.2%. In female cases, no spermatozoa were identified, and one case was PSA- and AP-positive in perianal swabs. Our findings indicate that PSA and AP tests are of limited value for the postmortem detection of spermatozoa in male subjects.

AB - The aim of this study was to clarify whether positive results for prostate-specific antigen (PSA) and acid phosphatase (AP) occur in postmortem swabs from the genito-anal region in males (n = 80; 4 regions) and females (n = 20; 3 regions) and to calculate the positive predictive value (PPV) concerning the presence of spermatozoa. In male subjects, the highest incidence of positive test results was found in urethral swabs (PSA 76%, AP 71%) and the lowest frequencies appeared in perianal and rectal swabs (15-20%). Microscopic evaluation for spermatozoa was positive between 39% in urethral swabs and 1% in rectal swabs. PPV regarding positive identification of spermatozoa was 33.3% for PSA and 31.5% for AP. The combination of both tests yielded a PPV of 38.2%. In female cases, no spermatozoa were identified, and one case was PSA- and AP-positive in perianal swabs. Our findings indicate that PSA and AP tests are of limited value for the postmortem detection of spermatozoa in male subjects.

U2 - 10.1111/1556-4029.12632

DO - 10.1111/1556-4029.12632

M3 - SCORING: Journal article

C2 - 25387394

VL - 60

SP - 41

EP - 44

JO - J FORENSIC SCI

JF - J FORENSIC SCI

SN - 0022-1198

IS - 1

ER -