Diagnostic value of PSA and AP tests for the detection of spermatozoa in postmortem swabs from the genital and anal region in males
Standard
Diagnostic value of PSA and AP tests for the detection of spermatozoa in postmortem swabs from the genital and anal region in males. / Weitzig, Laurence ; Schroeder, Ann Sophie; Augustin, Christa; Raupach, Tobias; Sehner, Susanne; Anders, Sven.
in: J FORENSIC SCI, Jahrgang 60, Nr. 1, 01.2015, S. 41-4.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Diagnostic value of PSA and AP tests for the detection of spermatozoa in postmortem swabs from the genital and anal region in males
AU - Weitzig, Laurence
AU - Schroeder, Ann Sophie
AU - Augustin, Christa
AU - Raupach, Tobias
AU - Sehner, Susanne
AU - Anders, Sven
N1 - © 2014 American Academy of Forensic Sciences.
PY - 2015/1
Y1 - 2015/1
N2 - The aim of this study was to clarify whether positive results for prostate-specific antigen (PSA) and acid phosphatase (AP) occur in postmortem swabs from the genito-anal region in males (n = 80; 4 regions) and females (n = 20; 3 regions) and to calculate the positive predictive value (PPV) concerning the presence of spermatozoa. In male subjects, the highest incidence of positive test results was found in urethral swabs (PSA 76%, AP 71%) and the lowest frequencies appeared in perianal and rectal swabs (15-20%). Microscopic evaluation for spermatozoa was positive between 39% in urethral swabs and 1% in rectal swabs. PPV regarding positive identification of spermatozoa was 33.3% for PSA and 31.5% for AP. The combination of both tests yielded a PPV of 38.2%. In female cases, no spermatozoa were identified, and one case was PSA- and AP-positive in perianal swabs. Our findings indicate that PSA and AP tests are of limited value for the postmortem detection of spermatozoa in male subjects.
AB - The aim of this study was to clarify whether positive results for prostate-specific antigen (PSA) and acid phosphatase (AP) occur in postmortem swabs from the genito-anal region in males (n = 80; 4 regions) and females (n = 20; 3 regions) and to calculate the positive predictive value (PPV) concerning the presence of spermatozoa. In male subjects, the highest incidence of positive test results was found in urethral swabs (PSA 76%, AP 71%) and the lowest frequencies appeared in perianal and rectal swabs (15-20%). Microscopic evaluation for spermatozoa was positive between 39% in urethral swabs and 1% in rectal swabs. PPV regarding positive identification of spermatozoa was 33.3% for PSA and 31.5% for AP. The combination of both tests yielded a PPV of 38.2%. In female cases, no spermatozoa were identified, and one case was PSA- and AP-positive in perianal swabs. Our findings indicate that PSA and AP tests are of limited value for the postmortem detection of spermatozoa in male subjects.
U2 - 10.1111/1556-4029.12632
DO - 10.1111/1556-4029.12632
M3 - SCORING: Journal article
C2 - 25387394
VL - 60
SP - 41
EP - 44
JO - J FORENSIC SCI
JF - J FORENSIC SCI
SN - 0022-1198
IS - 1
ER -