Developmental programming of allergic diseases.
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Developmental programming of allergic diseases. / Pincus, Maike; Arck, Petra.
in: Chem Immunol Allergy, Jahrgang 98, 2012, S. 70-84.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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RIS
TY - JOUR
T1 - Developmental programming of allergic diseases.
AU - Pincus, Maike
AU - Arck, Petra
PY - 2012
Y1 - 2012
N2 - Emerging evidence reveals that the incidence of allergic disorders commencing during childhood is influenced by pre-, peri- and early postnatal environmental challenges. We here highlight biomarkers involved in the purported interaction of a challenged intrauterine environment during pregnancy and the risk for allergies in the children later in life. We propose that the identification of biomarkers during pregnancy may allow early detection of children prone to develop allergies and possibly other chronic immune diseases. Subsequently, therapeutic interventions designed to prevent negative consequences of prenatal environmental challenges on children's immune system would be within reach.
AB - Emerging evidence reveals that the incidence of allergic disorders commencing during childhood is influenced by pre-, peri- and early postnatal environmental challenges. We here highlight biomarkers involved in the purported interaction of a challenged intrauterine environment during pregnancy and the risk for allergies in the children later in life. We propose that the identification of biomarkers during pregnancy may allow early detection of children prone to develop allergies and possibly other chronic immune diseases. Subsequently, therapeutic interventions designed to prevent negative consequences of prenatal environmental challenges on children's immune system would be within reach.
KW - Adult
KW - Humans
KW - Female
KW - Pregnancy
KW - Biological Markers/metabolism
KW - Autonomic Nervous System/growth & development/metabolism
KW - Endocrine System/growth & development/metabolism
KW - Hypersensitivity/etiology/immunology
KW - Immune System/growth & development/metabolism
KW - Prenatal Exposure Delayed Effects
KW - Adult
KW - Humans
KW - Female
KW - Pregnancy
KW - Biological Markers/metabolism
KW - Autonomic Nervous System/growth & development/metabolism
KW - Endocrine System/growth & development/metabolism
KW - Hypersensitivity/etiology/immunology
KW - Immune System/growth & development/metabolism
KW - Prenatal Exposure Delayed Effects
U2 - 10.1159/000336499
DO - 10.1159/000336499
M3 - SCORING: Journal article
VL - 98
SP - 70
EP - 84
ER -
