Development of the Metabolic Syndrome: Study Design and Baseline Data of the Lufthansa Prevention Study (LUPS), A Prospective Observational Cohort Survey.
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Development of the Metabolic Syndrome: Study Design and Baseline Data of the Lufthansa Prevention Study (LUPS), A Prospective Observational Cohort Survey. / Müller-Wieland, Dirk; Altenburg, Christiane; Becher, Heiko; Burchard, Janine; Frisch, Anett; Gebhard, Jan; Haas, Jutta; Harth, Volker; Heeren, Jörg; Hengelbrock, Johannes; von Karais, Maximilian; Knebel, Birgit; Kotzka, Jörg; Löwe, Bernd; Marx, Nikolaus; Pinnschmidt, Hans; Preisser, Alexandra; Rose, Matthias; Sawitzky-Rose, Barbara; Scheja, Ludger; Terschüren, Claudia; Töller, Monika; Vettorazzi, Eik; Wegscheider, Karl.
in: EXP CLIN ENDOCR DIAB, Jahrgang 128, Nr. 12, 12.2020, S. 777-787.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Development of the Metabolic Syndrome: Study Design and Baseline Data of the Lufthansa Prevention Study (LUPS), A Prospective Observational Cohort Survey.
AU - Müller-Wieland, Dirk
AU - Altenburg, Christiane
AU - Becher, Heiko
AU - Burchard, Janine
AU - Frisch, Anett
AU - Gebhard, Jan
AU - Haas, Jutta
AU - Harth, Volker
AU - Heeren, Jörg
AU - Hengelbrock, Johannes
AU - von Karais, Maximilian
AU - Knebel, Birgit
AU - Kotzka, Jörg
AU - Löwe, Bernd
AU - Marx, Nikolaus
AU - Pinnschmidt, Hans
AU - Preisser, Alexandra
AU - Rose, Matthias
AU - Sawitzky-Rose, Barbara
AU - Scheja, Ludger
AU - Terschüren, Claudia
AU - Töller, Monika
AU - Vettorazzi, Eik
AU - Wegscheider, Karl
N1 - Thieme. All rights reserved.
PY - 2020/12
Y1 - 2020/12
N2 - The Lufthansa Prevention Study (LUPS) study is a prospective observation of a healthy worker cohort to identify early changes in metabolism leading to the Metabolic Syndrome (MetS) and to analyze their relation to behavioral factors like nutrition, physical activity, psychological status, and to underlying genetic conditions. The LUPS study recruited a sample of 1.962 non-diabetic healthy adults between 25-60 years, employed at a flight base of Lufthansa Technik GmbH in Hamburg, Germany. Baseline assessments included anthropometric measures, blood and urine samples and medical history. Psychosocial variables, dietary habits and life-style risk factors were assessed via self-reported questionnaires.In this report we describe the study design and present baseline parameters including the prevalence of the MetS using different classification criteria. The MetS was present in 20% of male and 12% of female subjects according to the 'Harmonizing the metabolic syndrome' definition. The prevalence varies between 2.6% in male and 2.3% in female subjects up to 48% in male and 41% in female subjects according to different classification criteria of MetS.In conclusion, this first cross-sectional view on the LUPS data confirms the expectation that this cohort is rather healthy and thus provides the opportunity to analyze early changes associated with the development of the MetS. The LUPS study is registered as a clinical trial NCT01313156.
AB - The Lufthansa Prevention Study (LUPS) study is a prospective observation of a healthy worker cohort to identify early changes in metabolism leading to the Metabolic Syndrome (MetS) and to analyze their relation to behavioral factors like nutrition, physical activity, psychological status, and to underlying genetic conditions. The LUPS study recruited a sample of 1.962 non-diabetic healthy adults between 25-60 years, employed at a flight base of Lufthansa Technik GmbH in Hamburg, Germany. Baseline assessments included anthropometric measures, blood and urine samples and medical history. Psychosocial variables, dietary habits and life-style risk factors were assessed via self-reported questionnaires.In this report we describe the study design and present baseline parameters including the prevalence of the MetS using different classification criteria. The MetS was present in 20% of male and 12% of female subjects according to the 'Harmonizing the metabolic syndrome' definition. The prevalence varies between 2.6% in male and 2.3% in female subjects up to 48% in male and 41% in female subjects according to different classification criteria of MetS.In conclusion, this first cross-sectional view on the LUPS data confirms the expectation that this cohort is rather healthy and thus provides the opportunity to analyze early changes associated with the development of the MetS. The LUPS study is registered as a clinical trial NCT01313156.
KW - Journal Article
U2 - 10.1055/a-0767-6361
DO - 10.1055/a-0767-6361
M3 - SCORING: Journal article
C2 - 30477037
VL - 128
SP - 777
EP - 787
JO - EXP CLIN ENDOCR DIAB
JF - EXP CLIN ENDOCR DIAB
SN - 0947-7349
IS - 12
ER -