Determinants of direct and indirect costs in anorexia nervosa
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Determinants of direct and indirect costs in anorexia nervosa. / Stuhldreher, Nina; Wild, Beate; König, Hans-Helmut; Konnopka, Alexander; Zipfel, Stephan; Herzog, Wolfgang.
in: INT J EAT DISORDER, Jahrgang 48, Nr. 1, 01.2015, S. 139-46.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Determinants of direct and indirect costs in anorexia nervosa
AU - Stuhldreher, Nina
AU - Wild, Beate
AU - König, Hans-Helmut
AU - Konnopka, Alexander
AU - Zipfel, Stephan
AU - Herzog, Wolfgang
N1 - © 2014 Wiley Periodicals, Inc.
PY - 2015/1
Y1 - 2015/1
N2 - OBJECTIVE: To estimate direct and indirect costs of anorexia nervosa (AN), and to identify cost determinants.METHODS: In a subsample (n = 225) of the ANTOP trial (Anorexia Nervosa Treatment of OutPatients) health care utilization and productivity losses were assessed at baseline for the previous 3 months and monetarily valued. Included were females aged 18 years and older diagnosed with AN or subsyndromal AN, and a body mass index (BMI) between 15 and 18.5 kg/m(2) . To account for missing data multiple imputation was employed. Cost determinants were derived from generalized linear models with gamma distribution and log link function.RESULTS: Mean 3-months costs per patient amounted to €5,866 (SE = €576). The largest share of costs (€3,374) resulted from hospitalizations. Determinants of direct costs were analyzed separately for those with hospitalizations for AN, and those without. In the group only treated as outpatients, participants with binge/purge subtype, and those diseased for more than 6 years had higher costs. Moreover, costs were increased in patients with a comorbid mental disorder. In the group with hospitalizations, direct costs increased with BMI. BMI was measured at the end of the observation period, indicating that longer duration of treatment yielded higher weight gain. Indirect costs were not significantly associated with any disease-related characteristic.DISCUSSION: Costs resulting from health care utilization and productivity loss are substantial, although the sample studied had not received sufficient treatment. Future research should analyze the development of costs over time.
AB - OBJECTIVE: To estimate direct and indirect costs of anorexia nervosa (AN), and to identify cost determinants.METHODS: In a subsample (n = 225) of the ANTOP trial (Anorexia Nervosa Treatment of OutPatients) health care utilization and productivity losses were assessed at baseline for the previous 3 months and monetarily valued. Included were females aged 18 years and older diagnosed with AN or subsyndromal AN, and a body mass index (BMI) between 15 and 18.5 kg/m(2) . To account for missing data multiple imputation was employed. Cost determinants were derived from generalized linear models with gamma distribution and log link function.RESULTS: Mean 3-months costs per patient amounted to €5,866 (SE = €576). The largest share of costs (€3,374) resulted from hospitalizations. Determinants of direct costs were analyzed separately for those with hospitalizations for AN, and those without. In the group only treated as outpatients, participants with binge/purge subtype, and those diseased for more than 6 years had higher costs. Moreover, costs were increased in patients with a comorbid mental disorder. In the group with hospitalizations, direct costs increased with BMI. BMI was measured at the end of the observation period, indicating that longer duration of treatment yielded higher weight gain. Indirect costs were not significantly associated with any disease-related characteristic.DISCUSSION: Costs resulting from health care utilization and productivity loss are substantial, although the sample studied had not received sufficient treatment. Future research should analyze the development of costs over time.
KW - Adult
KW - Anorexia Nervosa
KW - Costs and Cost Analysis
KW - Female
KW - Germany
KW - Health Care Costs
KW - Hospitalization
KW - Humans
KW - Male
KW - Patient Acceptance of Health Care
KW - Research Design
KW - Time Factors
KW - Young Adult
U2 - 10.1002/eat.22274
DO - 10.1002/eat.22274
M3 - SCORING: Journal article
C2 - 24634140
VL - 48
SP - 139
EP - 146
JO - INT J EAT DISORDER
JF - INT J EAT DISORDER
SN - 0276-3478
IS - 1
ER -