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Design of a head coil for high resolution mouse brain perfusion imaging using magnetic particle imaging

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Design of a head coil for high resolution mouse brain perfusion imaging using magnetic particle imaging. / Graeser, Matthias; Ludewig, Peter; Szwargulski, Patryk; Foerger, Fynn; Liebing, Tom; Forkert, Nils Daniel; Thieben, Florian; Magnus, Tim; Knopp, Tobias.

in: PHYS MED BIOL, Jahrgang 65, Nr. 23, 23.12.2020, S. 235007.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Graeser, M, Ludewig, P, Szwargulski, P, Foerger, F, Liebing, T, Forkert, ND, Thieben, F, Magnus, T & Knopp, T 2020, 'Design of a head coil for high resolution mouse brain perfusion imaging using magnetic particle imaging', PHYS MED BIOL, Jg. 65, Nr. 23, S. 235007. https://doi.org/10.1088/1361-6560/abc09e

APA

Graeser, M., Ludewig, P., Szwargulski, P., Foerger, F., Liebing, T., Forkert, N. D., Thieben, F., Magnus, T., & Knopp, T. (2020). Design of a head coil for high resolution mouse brain perfusion imaging using magnetic particle imaging. PHYS MED BIOL, 65(23), 235007. https://doi.org/10.1088/1361-6560/abc09e

Vancouver

Graeser M, Ludewig P, Szwargulski P, Foerger F, Liebing T, Forkert ND et al. Design of a head coil for high resolution mouse brain perfusion imaging using magnetic particle imaging. PHYS MED BIOL. 2020 Dez 23;65(23):235007. https://doi.org/10.1088/1361-6560/abc09e

Bibtex

@article{c2423e61e6144c51a805fd0049c43d56,
title = "Design of a head coil for high resolution mouse brain perfusion imaging using magnetic particle imaging",
abstract = "Magnetic particle imaging (MPI) is a novel and versatile imaging modality developing toward human application. When up-scaling to human size, the sensitivity of the systems naturally drops as the coil sensitivity depends on the bore diameter. Thus, new methods to push the sensitivity limit further have to be investigated to cope for this loss. In this paper a dedicated surface coil for mice is developed, improving the sensitivity in cerebral imaging applications. Similar to magnetic resonance imaging the developed surface coil improves the sensitivity due to the closer vicinity to the region of interest. With the developed surface coil presented in this work, it is possible to image tracer samples containing only 896 pg[Formula: see text]  and detect even small vessels and anatomical structures within a wild type mouse model. As current sensitivity measures require a tracer system a new method for determining a sensitivity measure without this requirement is presented and verified to enable comparison between MPI receiver systems.",
author = "Matthias Graeser and Peter Ludewig and Patryk Szwargulski and Fynn Foerger and Tom Liebing and Forkert, {Nils Daniel} and Florian Thieben and Tim Magnus and Tobias Knopp",
note = "{\textcopyright} 2020 Institute of Physics and Engineering in Medicine.",
year = "2020",
month = dec,
day = "23",
doi = "10.1088/1361-6560/abc09e",
language = "English",
volume = "65",
pages = "235007",
journal = "PHYS MED BIOL",
issn = "0031-9155",
publisher = "IOP Publishing Ltd.",
number = "23",

}

RIS

TY - JOUR

T1 - Design of a head coil for high resolution mouse brain perfusion imaging using magnetic particle imaging

AU - Graeser, Matthias

AU - Ludewig, Peter

AU - Szwargulski, Patryk

AU - Foerger, Fynn

AU - Liebing, Tom

AU - Forkert, Nils Daniel

AU - Thieben, Florian

AU - Magnus, Tim

AU - Knopp, Tobias

N1 - © 2020 Institute of Physics and Engineering in Medicine.

PY - 2020/12/23

Y1 - 2020/12/23

N2 - Magnetic particle imaging (MPI) is a novel and versatile imaging modality developing toward human application. When up-scaling to human size, the sensitivity of the systems naturally drops as the coil sensitivity depends on the bore diameter. Thus, new methods to push the sensitivity limit further have to be investigated to cope for this loss. In this paper a dedicated surface coil for mice is developed, improving the sensitivity in cerebral imaging applications. Similar to magnetic resonance imaging the developed surface coil improves the sensitivity due to the closer vicinity to the region of interest. With the developed surface coil presented in this work, it is possible to image tracer samples containing only 896 pg[Formula: see text]  and detect even small vessels and anatomical structures within a wild type mouse model. As current sensitivity measures require a tracer system a new method for determining a sensitivity measure without this requirement is presented and verified to enable comparison between MPI receiver systems.

AB - Magnetic particle imaging (MPI) is a novel and versatile imaging modality developing toward human application. When up-scaling to human size, the sensitivity of the systems naturally drops as the coil sensitivity depends on the bore diameter. Thus, new methods to push the sensitivity limit further have to be investigated to cope for this loss. In this paper a dedicated surface coil for mice is developed, improving the sensitivity in cerebral imaging applications. Similar to magnetic resonance imaging the developed surface coil improves the sensitivity due to the closer vicinity to the region of interest. With the developed surface coil presented in this work, it is possible to image tracer samples containing only 896 pg[Formula: see text]  and detect even small vessels and anatomical structures within a wild type mouse model. As current sensitivity measures require a tracer system a new method for determining a sensitivity measure without this requirement is presented and verified to enable comparison between MPI receiver systems.

U2 - 10.1088/1361-6560/abc09e

DO - 10.1088/1361-6560/abc09e

M3 - SCORING: Journal article

C2 - 33049723

VL - 65

SP - 235007

JO - PHYS MED BIOL

JF - PHYS MED BIOL

SN - 0031-9155

IS - 23

ER -