Dendritic Cells and Their Role in Cardiovascular Diseases: A View on Human Studies

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Dendritic Cells and Their Role in Cardiovascular Diseases: A View on Human Studies. / Dieterlen, Maja-Theresa; John, Katja; Reichenspurner, Hermann; Mohr, Friedrich W; Barten, Markus J.

in: J IMMUNOL RES, Jahrgang 2016, 2016, S. 5946807.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ReviewForschung

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@article{9c9753210ccd409caa2837f906283636,
title = "Dendritic Cells and Their Role in Cardiovascular Diseases: A View on Human Studies",
abstract = "The antigen-presenting dendritic cells (DCs) are key to the immunological response, with different functions ascribed ranging from cellular immune activation to induction of tolerance. Such immunological responses are involved in the pathophysiological mechanisms of cardiovascular diseases, with DCs shown to play a role in atherosclerosis, hypertension, and heart failure and most notably following heart transplantation. A better understanding of the interplay between the immune system and cardiovascular diseases will therefore be critical for developing novel therapeutic treatments as well as innovative monitoring tools for disease progression. As such, the present review will provide an overview of DCs involvement in the pathophysiology of cardiovascular diseases and how targeting these cells may have beneficial effects for the prognosis of patients. ",
keywords = "Antigen Presentation, Antigens/immunology, Atherosclerosis/immunology, Clinical Trials as Topic, Coronary Artery Bypass, Dendritic Cells/immunology, Heart Failure/immunology, Heart Transplantation, Humans, Hypertension/immunology, Immune Tolerance, Immunity, Innate",
author = "Maja-Theresa Dieterlen and Katja John and Hermann Reichenspurner and Mohr, {Friedrich W} and Barten, {Markus J}",
year = "2016",
doi = "10.1155/2016/5946807",
language = "English",
volume = "2016",
pages = "5946807",
journal = "J IMMUNOL RES",
issn = "2314-8861",
publisher = "Hindawi Publishing Corporation",

}

RIS

TY - JOUR

T1 - Dendritic Cells and Their Role in Cardiovascular Diseases: A View on Human Studies

AU - Dieterlen, Maja-Theresa

AU - John, Katja

AU - Reichenspurner, Hermann

AU - Mohr, Friedrich W

AU - Barten, Markus J

PY - 2016

Y1 - 2016

N2 - The antigen-presenting dendritic cells (DCs) are key to the immunological response, with different functions ascribed ranging from cellular immune activation to induction of tolerance. Such immunological responses are involved in the pathophysiological mechanisms of cardiovascular diseases, with DCs shown to play a role in atherosclerosis, hypertension, and heart failure and most notably following heart transplantation. A better understanding of the interplay between the immune system and cardiovascular diseases will therefore be critical for developing novel therapeutic treatments as well as innovative monitoring tools for disease progression. As such, the present review will provide an overview of DCs involvement in the pathophysiology of cardiovascular diseases and how targeting these cells may have beneficial effects for the prognosis of patients.

AB - The antigen-presenting dendritic cells (DCs) are key to the immunological response, with different functions ascribed ranging from cellular immune activation to induction of tolerance. Such immunological responses are involved in the pathophysiological mechanisms of cardiovascular diseases, with DCs shown to play a role in atherosclerosis, hypertension, and heart failure and most notably following heart transplantation. A better understanding of the interplay between the immune system and cardiovascular diseases will therefore be critical for developing novel therapeutic treatments as well as innovative monitoring tools for disease progression. As such, the present review will provide an overview of DCs involvement in the pathophysiology of cardiovascular diseases and how targeting these cells may have beneficial effects for the prognosis of patients.

KW - Antigen Presentation

KW - Antigens/immunology

KW - Atherosclerosis/immunology

KW - Clinical Trials as Topic

KW - Coronary Artery Bypass

KW - Dendritic Cells/immunology

KW - Heart Failure/immunology

KW - Heart Transplantation

KW - Humans

KW - Hypertension/immunology

KW - Immune Tolerance

KW - Immunity, Innate

U2 - 10.1155/2016/5946807

DO - 10.1155/2016/5946807

M3 - SCORING: Review article

C2 - 27088098

VL - 2016

SP - 5946807

JO - J IMMUNOL RES

JF - J IMMUNOL RES

SN - 2314-8861

ER -