Deep brain stimulation for gait and postural symptoms in Parkinson's disease
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Deep brain stimulation for gait and postural symptoms in Parkinson's disease. / Pötter-Nerger, Monika; Volkmann, Jens.
in: MOVEMENT DISORD, Jahrgang 28, Nr. 11, 15.09.2013, S. 1609-15.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Deep brain stimulation for gait and postural symptoms in Parkinson's disease
AU - Pötter-Nerger, Monika
AU - Volkmann, Jens
N1 - © 2013 Movement Disorder Society.
PY - 2013/9/15
Y1 - 2013/9/15
N2 - In patients with Parkinson's disease, gait and balance difficulties have emerged as some of the main therapeutic concerns. During earlier stages of the disease, the dopamine-responsive aspects of gait disorder can be treated initially with dopaminergic drugs or deep brain stimulation. However, certain temporal aspects of parkinsonian gait disorder remain therapeutically resistant in both the short term and the long term. In this review, we summarize the effects of deep brain stimulation on gait and postural symptoms in the five currently available targets (subthalamic nucleus, globus pallidus, ventralis intermedius thalamic nucleus, pedunculopontine nucleus, and substantia nigra) and describe programming strategies for patients who are mainly disabled by gait problems.
AB - In patients with Parkinson's disease, gait and balance difficulties have emerged as some of the main therapeutic concerns. During earlier stages of the disease, the dopamine-responsive aspects of gait disorder can be treated initially with dopaminergic drugs or deep brain stimulation. However, certain temporal aspects of parkinsonian gait disorder remain therapeutically resistant in both the short term and the long term. In this review, we summarize the effects of deep brain stimulation on gait and postural symptoms in the five currently available targets (subthalamic nucleus, globus pallidus, ventralis intermedius thalamic nucleus, pedunculopontine nucleus, and substantia nigra) and describe programming strategies for patients who are mainly disabled by gait problems.
KW - Deep Brain Stimulation
KW - Gait Disorders, Neurologic
KW - Humans
KW - Parkinson Disease
KW - Postural Balance
KW - Sensation Disorders
U2 - 10.1002/mds.25677
DO - 10.1002/mds.25677
M3 - SCORING: Journal article
C2 - 24132849
VL - 28
SP - 1609
EP - 1615
JO - MOVEMENT DISORD
JF - MOVEMENT DISORD
SN - 0885-3185
IS - 11
ER -