Decreased active von Willebrand factor level owing to shear stress in aortic stenosis patients.
Beteiligte Einrichtungen
Abstract
Aortic stenosis patients often show bleeding complications. Previously, a prolonged platelet function analyzer (PFA-100) closure time was observed with plasma of severe aortic stenosis patients. To elucidate a possible role of circulating preactivated von Willebrand factor (VWF), we determined the level of VWF in its active, platelet-binding conformation in plasma of patients with aortic stenosis.
Bibliografische Daten
| Originalsprache | Englisch |
|---|---|
| Aufsatznummer | 5 |
| ISSN | 1538-7933 |
| Status | Veröffentlicht - 2011 |
| pubmed | 21352469 |
|---|
