De novo synthesis and lectin binding studies of unsaturated carba-pyranoses.

  • Timo Leermann
  • Oliver Block
  • Michael A L Podeschwa
  • Uwe Pfüller
  • Hans-Josef Altenbach

Abstract

Starting from branched para-benzoquinones a practical and highly flexible route is described for the preparation of unsaturated carbapyranoses. The potential of the synthesized galactose analogues to act as competitive inhibitors in lectin-carbohydrate interactions is investigated by means of Surface Plasmon Resonance (SPR) Spectroscopy.

Bibliografische Daten

OriginalspracheDeutsch
Aufsatznummer17
ISSN1477-0520
StatusVeröffentlicht - 2010
pubmed 20589308