Current practice and future directions in the diagnosis and acute treatment of ischaemic stroke
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Current practice and future directions in the diagnosis and acute treatment of ischaemic stroke. / Zerna, Charlotte; Thomalla, Götz; Campbell, Bruce C V; Rha, Joung-Ho; Hill, Michael D.
in: LANCET, Jahrgang 392, Nr. 10154, 06.10.2018, S. 1247-1256.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung
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TY - JOUR
T1 - Current practice and future directions in the diagnosis and acute treatment of ischaemic stroke
AU - Zerna, Charlotte
AU - Thomalla, Götz
AU - Campbell, Bruce C V
AU - Rha, Joung-Ho
AU - Hill, Michael D
N1 - Copyright © 2018 Elsevier Ltd. All rights reserved.
PY - 2018/10/6
Y1 - 2018/10/6
N2 - Even though stroke presents as a variety of clinical syndromes, neuroimaging is the most important biomarker to help differentiate between stroke subtypes and assess treatment eligibility. Therapeutic advances have led to intravenous thrombolysis with tissue-type plasminogen activator and endovascular treatment for proximal vessel occlusion in the anterior cerebral circulation being standard care for acute ischaemic stroke. Providing access to this care has implications for existing systems of care for stroke and their organisation and has reintroduced the possibility of adjuvant and neuroprotective treatment strategies in acute ischaemic stroke. The use of neuroimaging for patient selection and speed of diagnosis and delivery of treatment are the dominant themes of modern ischaemic stroke care.
AB - Even though stroke presents as a variety of clinical syndromes, neuroimaging is the most important biomarker to help differentiate between stroke subtypes and assess treatment eligibility. Therapeutic advances have led to intravenous thrombolysis with tissue-type plasminogen activator and endovascular treatment for proximal vessel occlusion in the anterior cerebral circulation being standard care for acute ischaemic stroke. Providing access to this care has implications for existing systems of care for stroke and their organisation and has reintroduced the possibility of adjuvant and neuroprotective treatment strategies in acute ischaemic stroke. The use of neuroimaging for patient selection and speed of diagnosis and delivery of treatment are the dominant themes of modern ischaemic stroke care.
KW - Brain Ischemia
KW - Emergency Service, Hospital
KW - Endovascular Procedures
KW - Humans
KW - Neuroimaging
KW - Stroke
KW - Thrombolytic Therapy
KW - Time Factors
KW - Tissue Plasminogen Activator
KW - Transportation of Patients
KW - Journal Article
KW - Review
U2 - 10.1016/S0140-6736(18)31874-9
DO - 10.1016/S0140-6736(18)31874-9
M3 - SCORING: Review article
C2 - 30319112
VL - 392
SP - 1247
EP - 1256
JO - LANCET
JF - LANCET
SN - 0140-6736
IS - 10154
ER -