Current developments and controversies: does the serotonin transporter gene-linked polymorphic region (5-HTTLPR) modulate the association between stress and depression?
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Current developments and controversies: does the serotonin transporter gene-linked polymorphic region (5-HTTLPR) modulate the association between stress and depression? / Wankerl, Matthis; Wüst, Stefan; Otte, Christian.
in: CURR OPIN PSYCHIATR, Jahrgang 23, Nr. 6, 6, 2010, S. 582-587.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Current developments and controversies: does the serotonin transporter gene-linked polymorphic region (5-HTTLPR) modulate the association between stress and depression?
AU - Wankerl, Matthis
AU - Wüst, Stefan
AU - Otte, Christian
PY - 2010
Y1 - 2010
N2 - Human observational studies have shown that, in interaction with life stress, the short or S-allele of the serotonin transporter gene-linked polymorphic region (5-HTTLPR) is associated with an enhanced risk for depression. However, this gene-by-environment interaction (G×E) has recently been questioned by two meta-analyses. We aim to provide an overview and appraisal of recent developments and controversies.
AB - Human observational studies have shown that, in interaction with life stress, the short or S-allele of the serotonin transporter gene-linked polymorphic region (5-HTTLPR) is associated with an enhanced risk for depression. However, this gene-by-environment interaction (G×E) has recently been questioned by two meta-analyses. We aim to provide an overview and appraisal of recent developments and controversies.
M3 - SCORING: Zeitschriftenaufsatz
VL - 23
SP - 582
EP - 587
JO - CURR OPIN PSYCHIATR
JF - CURR OPIN PSYCHIATR
SN - 0951-7367
IS - 6
M1 - 6
ER -
