CSF-tau, CSF-Abeta1-42, ApoE-genotype and clinical parameters in the diagnosis of Alzheimer's disease: combination of CSF-tau and MMSE yields highest sensitivity and specificity.
Beteiligte Einrichtungen
Abstract
This study evaluated the sensitivity and specificity of the cerebrospinal fluid (CSF) levels of tau-protein, amyloid-beta-peptide 1-42 (Abeta1-42), ApoE-genotype and the degree of cognitive decline as diagnostic markers for Alzheimer's disease (AD). Data was obtained from 105 AD patients and 68 controls. Median CSF-tau levels were increased (512 pg/ml vs. 145 pg/ml, p
Bibliografische Daten
| Originalsprache | Deutsch |
|---|---|
| Aufsatznummer | 10 |
| ISSN | 0300-9564 |
| Status | Veröffentlicht - 2003 |
| pubmed | 14523627 |
|---|
