PortalPublikationenCryptococcal meningoencephalitis relapse after an eight-year...

Cryptococcal meningoencephalitis relapse after an eight-year delay: an interplay of infection and immune reconstitution

Standard

Cryptococcal meningoencephalitis relapse after an eight-year delay: an interplay of infection and immune reconstitution. / Katchanov, Juri; Blechschmidt, Cristiane; Nielsen, Kirsten; Branding, Gordian; Arastéh, Keikawus; Tintelnot, Kathrin; Meintjes, Graeme; Boulware, David R; Stocker, Hartmut.

in: INT J STD AIDS, Jahrgang 26, Nr. 12, 10.2015, S. 912-4.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Katchanov, J, Blechschmidt, C, Nielsen, K, Branding, G, Arastéh, K, Tintelnot, K, Meintjes, G, Boulware, DR & Stocker, H 2015, 'Cryptococcal meningoencephalitis relapse after an eight-year delay: an interplay of infection and immune reconstitution', INT J STD AIDS, Jg. 26, Nr. 12, S. 912-4. https://doi.org/10.1177/0956462414563630

APA

Katchanov, J., Blechschmidt, C., Nielsen, K., Branding, G., Arastéh, K., Tintelnot, K., Meintjes, G., Boulware, D. R., & Stocker, H. (2015). Cryptococcal meningoencephalitis relapse after an eight-year delay: an interplay of infection and immune reconstitution. INT J STD AIDS, 26(12), 912-4. https://doi.org/10.1177/0956462414563630

Vancouver

Katchanov J, Blechschmidt C, Nielsen K, Branding G, Arastéh K, Tintelnot K et al. Cryptococcal meningoencephalitis relapse after an eight-year delay: an interplay of infection and immune reconstitution. INT J STD AIDS. 2015 Okt;26(12):912-4. https://doi.org/10.1177/0956462414563630

Bibtex

@article{cb388192390044069d8c1988801cd441,
title = "Cryptococcal meningoencephalitis relapse after an eight-year delay: an interplay of infection and immune reconstitution",
abstract = "We report a case of a symptomatic relapse of HIV-related cryptococcal meningoencephalitis eight years after the first diagnosis on the background of immune reconstitution. The findings as well as the clinical course suggests a combination of smouldering localised infection and enhanced inflammatory reaction related to immune restoration due to antiretroviral therapy. A combination of antifungal and anti-inflammatory therapy resulted in clinical and radiological improvement. Our case challenges the concept that immune reconstitution inflammatory syndrome and microbiological relapse are dichotomous entities.",
keywords = "AIDS-Related Opportunistic Infections, Anti-HIV Agents, Antifungal Agents, Antiretroviral Therapy, Highly Active, Biopsy, Brain, Cryptococcus neoformans, Female, Fluconazole, HIV Infections, Humans, Immune Reconstitution Inflammatory Syndrome, Male, Medication Adherence, Meningitis, Cryptococcal, Recurrence, Treatment Outcome",
author = "Juri Katchanov and Cristiane Blechschmidt and Kirsten Nielsen and Gordian Branding and Keikawus Arast{\'e}h and Kathrin Tintelnot and Graeme Meintjes and Boulware, {David R} and Hartmut Stocker",
note = "{\textcopyright} The Author(s) 2015.",
year = "2015",
month = oct,
doi = "10.1177/0956462414563630",
language = "English",
volume = "26",
pages = "912--4",
journal = "INT J STD AIDS",
issn = "0956-4624",
publisher = "SAGE Publications",
number = "12",

}

RIS

TY - JOUR

T1 - Cryptococcal meningoencephalitis relapse after an eight-year delay: an interplay of infection and immune reconstitution

AU - Katchanov, Juri

AU - Blechschmidt, Cristiane

AU - Nielsen, Kirsten

AU - Branding, Gordian

AU - Arastéh, Keikawus

AU - Tintelnot, Kathrin

AU - Meintjes, Graeme

AU - Boulware, David R

AU - Stocker, Hartmut

N1 - © The Author(s) 2015.

PY - 2015/10

Y1 - 2015/10

N2 - We report a case of a symptomatic relapse of HIV-related cryptococcal meningoencephalitis eight years after the first diagnosis on the background of immune reconstitution. The findings as well as the clinical course suggests a combination of smouldering localised infection and enhanced inflammatory reaction related to immune restoration due to antiretroviral therapy. A combination of antifungal and anti-inflammatory therapy resulted in clinical and radiological improvement. Our case challenges the concept that immune reconstitution inflammatory syndrome and microbiological relapse are dichotomous entities.

AB - We report a case of a symptomatic relapse of HIV-related cryptococcal meningoencephalitis eight years after the first diagnosis on the background of immune reconstitution. The findings as well as the clinical course suggests a combination of smouldering localised infection and enhanced inflammatory reaction related to immune restoration due to antiretroviral therapy. A combination of antifungal and anti-inflammatory therapy resulted in clinical and radiological improvement. Our case challenges the concept that immune reconstitution inflammatory syndrome and microbiological relapse are dichotomous entities.

KW - AIDS-Related Opportunistic Infections

KW - Anti-HIV Agents

KW - Antifungal Agents

KW - Antiretroviral Therapy, Highly Active

KW - Biopsy

KW - Brain

KW - Cryptococcus neoformans

KW - Female

KW - Fluconazole

KW - HIV Infections

KW - Humans

KW - Immune Reconstitution Inflammatory Syndrome

KW - Male

KW - Medication Adherence

KW - Meningitis, Cryptococcal

KW - Recurrence

KW - Treatment Outcome

U2 - 10.1177/0956462414563630

DO - 10.1177/0956462414563630

M3 - SCORING: Journal article

C2 - 25505049

VL - 26

SP - 912

EP - 914

JO - INT J STD AIDS

JF - INT J STD AIDS

SN - 0956-4624

IS - 12

ER -