Critical appraisal of the 2020 ESC guideline recommendations on diagnosis and risk assessment in patients with suspected non-ST-segment elevation acute coronary syndrome
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Critical appraisal of the 2020 ESC guideline recommendations on diagnosis and risk assessment in patients with suspected non-ST-segment elevation acute coronary syndrome. / Giannitsis, Evangelos; Blankenberg, Stefan; Christenson, Robert H; Frey, Norbert; von Haehling, Stephan; Hamm, Christian W; Inoue, Kenji; Katus, Hugo A; Lee, Chien-Chang; McCord, James; Möckel, Martin; Chieh, Jack Tan Wei; Tubaro, Marco; Wollert, Kai C; Huber, Kurt.
in: CLIN RES CARDIOL, Jahrgang 110, Nr. 9, 09.2021, S. 1353-1368.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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T1 - Critical appraisal of the 2020 ESC guideline recommendations on diagnosis and risk assessment in patients with suspected non-ST-segment elevation acute coronary syndrome
AU - Giannitsis, Evangelos
AU - Blankenberg, Stefan
AU - Christenson, Robert H
AU - Frey, Norbert
AU - von Haehling, Stephan
AU - Hamm, Christian W
AU - Inoue, Kenji
AU - Katus, Hugo A
AU - Lee, Chien-Chang
AU - McCord, James
AU - Möckel, Martin
AU - Chieh, Jack Tan Wei
AU - Tubaro, Marco
AU - Wollert, Kai C
AU - Huber, Kurt
N1 - © 2021. The Author(s).
PY - 2021/9
Y1 - 2021/9
N2 - Multiple new recommendations have been introduced in the 2020 ESC guidelines for the management of acute coronary syndromes with a focus on diagnosis, prognosis, and management of patients presenting without persistent ST-segment elevation. Most recommendations are supported by high-quality scientific evidence. The guidelines provide solutions to overcome obstacles presumed to complicate a convenient interpretation of troponin results such as age-, or sex-specific cutoffs, and to give practical advice to overcome delays of laboratory reporting. However, in some areas, scientific support is less well documented or even missing, and other areas are covered rather by expert opinion or subjective recommendations. We aim to provide a critical appraisal on several recommendations, mainly related to the diagnostic and prognostic assessment, highlighting the discrepancies between Guideline recommendations and the existing scientific evidence.
AB - Multiple new recommendations have been introduced in the 2020 ESC guidelines for the management of acute coronary syndromes with a focus on diagnosis, prognosis, and management of patients presenting without persistent ST-segment elevation. Most recommendations are supported by high-quality scientific evidence. The guidelines provide solutions to overcome obstacles presumed to complicate a convenient interpretation of troponin results such as age-, or sex-specific cutoffs, and to give practical advice to overcome delays of laboratory reporting. However, in some areas, scientific support is less well documented or even missing, and other areas are covered rather by expert opinion or subjective recommendations. We aim to provide a critical appraisal on several recommendations, mainly related to the diagnostic and prognostic assessment, highlighting the discrepancies between Guideline recommendations and the existing scientific evidence.
KW - Acute Coronary Syndrome/diagnosis
KW - Europe
KW - Female
KW - Humans
KW - Male
KW - Non-ST Elevated Myocardial Infarction/diagnosis
KW - Practice Guidelines as Topic
KW - Prognosis
KW - Risk Assessment
KW - Troponin/metabolism
U2 - 10.1007/s00392-021-01821-2
DO - 10.1007/s00392-021-01821-2
M3 - SCORING: Journal article
C2 - 33635437
VL - 110
SP - 1353
EP - 1368
JO - CLIN RES CARDIOL
JF - CLIN RES CARDIOL
SN - 1861-0684
IS - 9
ER -