PortalPublikationenC-reactive protein, pre- and postdexamethasone cortisol leve...

C-reactive protein, pre- and postdexamethasone cortisol levels in post-traumatic stress disorder

Standard

C-reactive protein, pre- and postdexamethasone cortisol levels in post-traumatic stress disorder. / Spitzer, Carsten; Wibisono, Dennis; Terfehr, Kirsten; Löwe, Bernd; Otte, Christian; Wingenfeld, Katja.

in: NORD J PSYCHIAT, Jahrgang 68, Nr. 5, 01.07.2014, S. 296-299.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Spitzer, C, Wibisono, D, Terfehr, K, Löwe, B, Otte, C & Wingenfeld, K 2014, 'C-reactive protein, pre- and postdexamethasone cortisol levels in post-traumatic stress disorder', NORD J PSYCHIAT, Jg. 68, Nr. 5, S. 296-299. https://doi.org/10.3109/08039488.2013.844271

APA

Spitzer, C., Wibisono, D., Terfehr, K., Löwe, B., Otte, C., & Wingenfeld, K. (2014). C-reactive protein, pre- and postdexamethasone cortisol levels in post-traumatic stress disorder. NORD J PSYCHIAT, 68(5), 296-299. https://doi.org/10.3109/08039488.2013.844271

Vancouver

Spitzer C, Wibisono D, Terfehr K, Löwe B, Otte C, Wingenfeld K. C-reactive protein, pre- and postdexamethasone cortisol levels in post-traumatic stress disorder. NORD J PSYCHIAT. 2014 Jul 1;68(5):296-299. https://doi.org/10.3109/08039488.2013.844271

Bibtex

@article{86baaa37bc404cbe93c64acc073d3cb0,
title = "C-reactive protein, pre- and postdexamethasone cortisol levels in post-traumatic stress disorder",
abstract = "Abstract Background: Dysregulations of the hypothalamic-pituitary-adrenal axis may impact inflammatory processes in post-traumatic stress disorder (PTSD), possibly resulting in a low-grade inflammation as reflected by elevated levels of C-reactive protein (CRP). Methods: Serum CRP levels and salivary cortisol before and after the dexamethasone suppression test (DST) were assessed in 50 inpatients with main diagnoses PTSD, major depressive disorder or borderline personality disorder. Results: A strong trend for lower CRP levels was found in PTSD positive individuals compared with patients without PTSD. Conclusions: Our study does not support the hypothesis of elevated serum CRP levels in PTSD compared with other psychiatric patients. However, a dysbalanced immune system with suppressed CRP might contribute to the elevated somatic comorbidity in PTSD.",
author = "Carsten Spitzer and Dennis Wibisono and Kirsten Terfehr and Bernd L{\"o}we and Christian Otte and Katja Wingenfeld",
year = "2014",
month = jul,
day = "1",
doi = "10.3109/08039488.2013.844271",
language = "English",
volume = "68",
pages = "296--299",
journal = "NORD J PSYCHIAT",
issn = "0803-9488",
publisher = "informa healthcare",
number = "5",

}

RIS

TY - JOUR

T1 - C-reactive protein, pre- and postdexamethasone cortisol levels in post-traumatic stress disorder

AU - Spitzer, Carsten

AU - Wibisono, Dennis

AU - Terfehr, Kirsten

AU - Löwe, Bernd

AU - Otte, Christian

AU - Wingenfeld, Katja

PY - 2014/7/1

Y1 - 2014/7/1

N2 - Abstract Background: Dysregulations of the hypothalamic-pituitary-adrenal axis may impact inflammatory processes in post-traumatic stress disorder (PTSD), possibly resulting in a low-grade inflammation as reflected by elevated levels of C-reactive protein (CRP). Methods: Serum CRP levels and salivary cortisol before and after the dexamethasone suppression test (DST) were assessed in 50 inpatients with main diagnoses PTSD, major depressive disorder or borderline personality disorder. Results: A strong trend for lower CRP levels was found in PTSD positive individuals compared with patients without PTSD. Conclusions: Our study does not support the hypothesis of elevated serum CRP levels in PTSD compared with other psychiatric patients. However, a dysbalanced immune system with suppressed CRP might contribute to the elevated somatic comorbidity in PTSD.

AB - Abstract Background: Dysregulations of the hypothalamic-pituitary-adrenal axis may impact inflammatory processes in post-traumatic stress disorder (PTSD), possibly resulting in a low-grade inflammation as reflected by elevated levels of C-reactive protein (CRP). Methods: Serum CRP levels and salivary cortisol before and after the dexamethasone suppression test (DST) were assessed in 50 inpatients with main diagnoses PTSD, major depressive disorder or borderline personality disorder. Results: A strong trend for lower CRP levels was found in PTSD positive individuals compared with patients without PTSD. Conclusions: Our study does not support the hypothesis of elevated serum CRP levels in PTSD compared with other psychiatric patients. However, a dysbalanced immune system with suppressed CRP might contribute to the elevated somatic comorbidity in PTSD.

U2 - 10.3109/08039488.2013.844271

DO - 10.3109/08039488.2013.844271

M3 - SCORING: Journal article

C2 - 24134123

VL - 68

SP - 296

EP - 299

JO - NORD J PSYCHIAT

JF - NORD J PSYCHIAT

SN - 0803-9488

IS - 5

ER -