CPT SIOP
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CPT SIOP. / Wolff, Johannes; Hasselblatt, Martin; Hartung, Stefan; Powell, Martha; Garami, Miklos; Traunecker, Heidi; Thall, Peter; Mahajan, Anita; Kordes, Uwe; Sumerauer, David.
in: J NEURO-ONCOL, Jahrgang 14, 2012, S. i153.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung
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TY - JOUR
T1 - CPT SIOP
AU - Wolff, Johannes
AU - Hasselblatt, Martin
AU - Hartung, Stefan
AU - Powell, Martha
AU - Garami, Miklos
AU - Traunecker, Heidi
AU - Thall, Peter
AU - Mahajan, Anita
AU - Kordes, Uwe
AU - Sumerauer, David
PY - 2012
Y1 - 2012
N2 - PURPOSE: Choroid plexus tumors - papillomas and atypical papillomas (CPP) and carcinomas (CPP) are rare tumors originating from choroid plexus. The incidence is highest in children. Treatment, as it is common in other rare tumors, depends on a specification of diagnosis and experience collected from a case by case method and by global effort of many specialists. The International Registry of Choroid Plexus Tumors allows that as a powerful tool for diagnosis, treatment, incidence and survival information and improving the care by supporting prospective randomized protocols, follow-ups and literature monitoring. METHOD: 233 patients with choroid plexus tumors were registered from 173 nations from January 2000 until now. Reference pathology was completed in more than 150 cases. RESULTS: The projected 5-year overall survival in CPP is 100 % and event free survival ( EFS) 88%, OS in APP is 91% and EFS in APP is 79%, OS in CPC is 48% and EFS in CPC is 43%. The outcome in patients that received radiation is better than of those without radiation. The effect of surgery cannot be detected any more- patients with partial resection do as well as those with complete resection. By CPT-SIOP-2000 chemotherapy makes no difference in the outcome compare to other treatments - more detailed analysis is warranted for CPT SIOP2012 Meeting. The protocol CPT-SIOP-2009 has opened in Boston, but the accrual is slow. CONCLUSION: While there is overlap CPT 2000 and CPT 2009 Registries, the next protocol CPT-SIOP 2009 should be opened in more centers and opening of new world-wide centers is being encouraged
AB - PURPOSE: Choroid plexus tumors - papillomas and atypical papillomas (CPP) and carcinomas (CPP) are rare tumors originating from choroid plexus. The incidence is highest in children. Treatment, as it is common in other rare tumors, depends on a specification of diagnosis and experience collected from a case by case method and by global effort of many specialists. The International Registry of Choroid Plexus Tumors allows that as a powerful tool for diagnosis, treatment, incidence and survival information and improving the care by supporting prospective randomized protocols, follow-ups and literature monitoring. METHOD: 233 patients with choroid plexus tumors were registered from 173 nations from January 2000 until now. Reference pathology was completed in more than 150 cases. RESULTS: The projected 5-year overall survival in CPP is 100 % and event free survival ( EFS) 88%, OS in APP is 91% and EFS in APP is 79%, OS in CPC is 48% and EFS in CPC is 43%. The outcome in patients that received radiation is better than of those without radiation. The effect of surgery cannot be detected any more- patients with partial resection do as well as those with complete resection. By CPT-SIOP-2000 chemotherapy makes no difference in the outcome compare to other treatments - more detailed analysis is warranted for CPT SIOP2012 Meeting. The protocol CPT-SIOP-2009 has opened in Boston, but the accrual is slow. CONCLUSION: While there is overlap CPT 2000 and CPT 2009 Registries, the next protocol CPT-SIOP 2009 should be opened in more centers and opening of new world-wide centers is being encouraged
KW - conf, cpt, qot
U2 - 10.1093/neuonc/nos108
DO - 10.1093/neuonc/nos108
M3 - SCORING: Journal article
VL - 14
SP - i153
JO - J NEURO-ONCOL
JF - J NEURO-ONCOL
SN - 0167-594X
ER -
