Cost of illness in patients with Gilles de la Tourette's syndrome.
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Cost of illness in patients with Gilles de la Tourette's syndrome. / Dodel, Ines; Reese, Jens Peter; Müller, Norbert; Münchau, Alexander; Balzer-Geldsetzer, Monika; Wasem, Jürgen; Oertel, Wolfgang H; Dodel, Richard; Müller-Vahl, Kirsten.
in: J NEUROL, Jahrgang 257, Nr. 7, 7, 2010, S. 1055-1061.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Cost of illness in patients with Gilles de la Tourette's syndrome.
AU - Dodel, Ines
AU - Reese, Jens Peter
AU - Müller, Norbert
AU - Münchau, Alexander
AU - Balzer-Geldsetzer, Monika
AU - Wasem, Jürgen
AU - Oertel, Wolfgang H
AU - Dodel, Richard
AU - Müller-Vahl, Kirsten
PY - 2010
Y1 - 2010
N2 - We evaluated the health economic burden of patients with Gilles de la Tourette's syndrome (GTS) in Germany over a 3-month observation period. Direct and indirect costs were evaluated in 200 outpatients with GTS (mean age 35 +/- 11.5 years) in Germany. Patients were recruited from three outpatient departments that specialized in GTS and completed a semi-structured and self-rating interview with questionnaires screening for direct and indirect medical and non-medical costs, health status, depression, amount and severity of symptoms. Costs were obtained from various German medical economic resources. Indirect costs for lost productivity were calculated using the human capital approach. Costs were calculated from the point of view of healthcare and transfer payment providers and the individual patient. Multivariate regression analyses were performed to identify independent cost predictors. Costs are in year 2006-2007 values. Direct costs were 620 +/- 1,697.1euro, including rehabilitation 98.8 +/- 993.6euro, hospitalization 195.8 +/- 1,267.8euro, outpatient treatment 14.0 +/- 40.6euro, ancillary treatment 51.9 +/- 137.4euro. Drug costs were 223.1 +/- 430.4. The indirect medical costs amounted to 2,511.3 +/- 3,809.5euro for productivity loss and to 220.0 +/- 1,092euro for absenteeism. The following variables were found to impact on direct costs: employment status, occupational advancement, depression, quality of life, age. Disease severity had no influence on cost. Because of the earlier age of disease onset, indirect costs are higher than direct costs. Interestingly, disease severity did not influence the resource need in this population. Unfortunately, no cost of illness studies are available for comparison. Further health economic studies, especially cost-effectiveness studies, are necessary for a basis for rational resource allocation.
AB - We evaluated the health economic burden of patients with Gilles de la Tourette's syndrome (GTS) in Germany over a 3-month observation period. Direct and indirect costs were evaluated in 200 outpatients with GTS (mean age 35 +/- 11.5 years) in Germany. Patients were recruited from three outpatient departments that specialized in GTS and completed a semi-structured and self-rating interview with questionnaires screening for direct and indirect medical and non-medical costs, health status, depression, amount and severity of symptoms. Costs were obtained from various German medical economic resources. Indirect costs for lost productivity were calculated using the human capital approach. Costs were calculated from the point of view of healthcare and transfer payment providers and the individual patient. Multivariate regression analyses were performed to identify independent cost predictors. Costs are in year 2006-2007 values. Direct costs were 620 +/- 1,697.1euro, including rehabilitation 98.8 +/- 993.6euro, hospitalization 195.8 +/- 1,267.8euro, outpatient treatment 14.0 +/- 40.6euro, ancillary treatment 51.9 +/- 137.4euro. Drug costs were 223.1 +/- 430.4. The indirect medical costs amounted to 2,511.3 +/- 3,809.5euro for productivity loss and to 220.0 +/- 1,092euro for absenteeism. The following variables were found to impact on direct costs: employment status, occupational advancement, depression, quality of life, age. Disease severity had no influence on cost. Because of the earlier age of disease onset, indirect costs are higher than direct costs. Interestingly, disease severity did not influence the resource need in this population. Unfortunately, no cost of illness studies are available for comparison. Further health economic studies, especially cost-effectiveness studies, are necessary for a basis for rational resource allocation.
KW - Adult
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - numerical data
KW - Adolescent
KW - Questionnaires
KW - Young Adult
KW - Severity of Illness Index
KW - Cost of Illness
KW - Health Care Costs statistics
KW - Germany epidemiology
KW - Age of Onset
KW - Quality of Life psychology
KW - Depression economics
KW - Employment economics
KW - Tourette Syndrome economics
KW - Adult
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - numerical data
KW - Adolescent
KW - Questionnaires
KW - Young Adult
KW - Severity of Illness Index
KW - Cost of Illness
KW - Health Care Costs statistics
KW - Germany epidemiology
KW - Age of Onset
KW - Quality of Life psychology
KW - Depression economics
KW - Employment economics
KW - Tourette Syndrome economics
M3 - SCORING: Zeitschriftenaufsatz
VL - 257
SP - 1055
EP - 1061
JO - J NEUROL
JF - J NEUROL
SN - 0340-5354
IS - 7
M1 - 7
ER -
