Correlation of apparent diffusion coefficient and computed tomography density in acute ischemic stroke.
Standard
Correlation of apparent diffusion coefficient and computed tomography density in acute ischemic stroke. / Kucinski, Thomas; Väterlein, Ole; Glauche, Volkmar; Fiehler, Jens; Klotz, Ernst; Eckert, Bernd; Koch, Christoph; Röther, Joachim; Zeumer, Hermann.
in: STROKE, Jahrgang 33, Nr. 7, 7, 2002, S. 1786-1791.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Correlation of apparent diffusion coefficient and computed tomography density in acute ischemic stroke.
AU - Kucinski, Thomas
AU - Väterlein, Ole
AU - Glauche, Volkmar
AU - Fiehler, Jens
AU - Klotz, Ernst
AU - Eckert, Bernd
AU - Koch, Christoph
AU - Röther, Joachim
AU - Zeumer, Hermann
PY - 2002
Y1 - 2002
N2 - BACKGROUND AND PURPOSE: Diffusion-weighted MR imaging is very sensitive for the detection of restricted molecular water diffusion in acute ischemic stroke. CT is sensitive to net water uptake in ischemic edema. We compared the decrease in the apparent diffusion coefficient (ADC) in diffusion-weighted MR imaging with CT density changes to study the correlation between diffusion restriction and water uptake in acute stroke patients. METHODS: Twenty-five patients with acute ischemic stroke of the anterior cerebral circulation underwent MR and CT imaging 1.3 to 5.4 hours after symptom onset. ADC and CT data were transferred into a common 3-dimensional space, and regions of decreased ADC (dADC) were superimposed onto the corresponding CT. Mean values of ADC and Hounsfield units (HU) were determined in comparison with the nonaffected hemisphere. RESULTS: Mean decrease in ADC (dADC) was 170+/-53x 10(-6) mm2/s and corresponded to a decrease (dCT) in CT density of 1.3+/-0.7 HU. dCT showed a continuous linear decrease of 0.4 HU/h (r=0.55, P
AB - BACKGROUND AND PURPOSE: Diffusion-weighted MR imaging is very sensitive for the detection of restricted molecular water diffusion in acute ischemic stroke. CT is sensitive to net water uptake in ischemic edema. We compared the decrease in the apparent diffusion coefficient (ADC) in diffusion-weighted MR imaging with CT density changes to study the correlation between diffusion restriction and water uptake in acute stroke patients. METHODS: Twenty-five patients with acute ischemic stroke of the anterior cerebral circulation underwent MR and CT imaging 1.3 to 5.4 hours after symptom onset. ADC and CT data were transferred into a common 3-dimensional space, and regions of decreased ADC (dADC) were superimposed onto the corresponding CT. Mean values of ADC and Hounsfield units (HU) were determined in comparison with the nonaffected hemisphere. RESULTS: Mean decrease in ADC (dADC) was 170+/-53x 10(-6) mm2/s and corresponded to a decrease (dCT) in CT density of 1.3+/-0.7 HU. dCT showed a continuous linear decrease of 0.4 HU/h (r=0.55, P
M3 - SCORING: Zeitschriftenaufsatz
VL - 33
SP - 1786
EP - 1791
JO - STROKE
JF - STROKE
SN - 0039-2499
IS - 7
M1 - 7
ER -