Controversies in the management of localized prostate cancer: Radical prostatectomy still the standard of care.
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Controversies in the management of localized prostate cancer: Radical prostatectomy still the standard of care. / Budäus, Lars; Huland, Hartwig; Graefen, Markus; Radiotherapy, On Behalf Of AROME Association Of; ArEa, Oncology Of The Mediterranean.
in: CRIT REV ONCOL HEMAT, Jahrgang 84(Suppl. 1), 2012, S. 24-29.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Controversies in the management of localized prostate cancer: Radical prostatectomy still the standard of care.
AU - Budäus, Lars
AU - Huland, Hartwig
AU - Graefen, Markus
AU - Radiotherapy, On Behalf Of AROME Association Of
AU - ArEa, Oncology Of The Mediterranean
PY - 2012
Y1 - 2012
N2 - The optimal treatment for clinically localized prostate cancer is an ongoing subject of controversy. Treatment decisions must take tumour staging, risk assessment, life expectancy and consideration of the major side effects of multiple available treatment regimens into account. Despite technical advances reduced the side effects of radiation therapy, the majority of patients with newly diagnosed organ confined prostate cancer decide to undergo radical prostatectomy. Refinements of radical prostatectomy surgical techniques during the last decade are influenced by better understanding of the anatomy of the small pelvis and resulted in excellent functional and oncological outcomes. Additionally, the surgeons experience was identified as a key determinant for improved surgical outcomes. Recently, retrospective studies revealed that also patients with locally advanced disease benefit from radical prostatectomy. Advantages of radical prostatectomy include a precise pathological staging that assesses the need for additional therapies. Moreover, PSA can easily be used as an accurate surrogate marker during follow-up in such patients.
AB - The optimal treatment for clinically localized prostate cancer is an ongoing subject of controversy. Treatment decisions must take tumour staging, risk assessment, life expectancy and consideration of the major side effects of multiple available treatment regimens into account. Despite technical advances reduced the side effects of radiation therapy, the majority of patients with newly diagnosed organ confined prostate cancer decide to undergo radical prostatectomy. Refinements of radical prostatectomy surgical techniques during the last decade are influenced by better understanding of the anatomy of the small pelvis and resulted in excellent functional and oncological outcomes. Additionally, the surgeons experience was identified as a key determinant for improved surgical outcomes. Recently, retrospective studies revealed that also patients with locally advanced disease benefit from radical prostatectomy. Advantages of radical prostatectomy include a precise pathological staging that assesses the need for additional therapies. Moreover, PSA can easily be used as an accurate surrogate marker during follow-up in such patients.
M3 - SCORING: Journal article
VL - 84(Suppl. 1)
SP - 24
EP - 29
JO - CRIT REV ONCOL HEMAT
JF - CRIT REV ONCOL HEMAT
SN - 1040-8428
ER -
