Contemporary prostate cancer prevalence among T1c biopsy-referred men with a prostate-specific antigen level <or = 4.0 ng per milliliter.
Standard
Contemporary prostate cancer prevalence among T1c biopsy-referred men with a prostate-specific antigen level <or = 4.0 ng per milliliter. / Ahyai, Sascha; Graefen, Markus; Steuber, Thomas; Haese, Alexander; Schlomm, Thorsten; Walz, Jochen; Köllermann, Jens; Briganti, Alberto; Zacharias, Mario; Friedrich, Martin; Karakiewicz, Pierre I; Montorsi, Francesco; Huland, Hartwig; Chun, Felix.
in: EUR UROL, Jahrgang 53, Nr. 4, 4, 2008, S. 750-757.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Contemporary prostate cancer prevalence among T1c biopsy-referred men with a prostate-specific antigen level <or = 4.0 ng per milliliter.
AU - Ahyai, Sascha
AU - Graefen, Markus
AU - Steuber, Thomas
AU - Haese, Alexander
AU - Schlomm, Thorsten
AU - Walz, Jochen
AU - Köllermann, Jens
AU - Briganti, Alberto
AU - Zacharias, Mario
AU - Friedrich, Martin
AU - Karakiewicz, Pierre I
AU - Montorsi, Francesco
AU - Huland, Hartwig
AU - Chun, Felix
PY - 2008
Y1 - 2008
N2 - OBJECTIVE: To investigate the prostate cancer (PCa) prevalence and risk factors of men with prostate-specific antigen (PSA) level or =7. RESULTS: Overall PCa detection rate was 23.1%. The majority had a biopsy Gleason sum of 6 (79.5%) and 20.5% had a biopsy Gleason sum> or =7. Total PSA (tPSA) and percentage of free PSA (%fPSA) were statistically significantly different in men with and without PCa (all p or = 7 at biopsy, %fPSA and prostate volume represented independent and most informative risk factors. CONCLUSION: Our data demonstrate that a substantial percentage (23.1%) of men with a PSA<or =4.0 ng/ml and an unsuspicious DRE in a biopsy referral population harbor PCa, with 20.5% being high grade. Low %fPSA and low prostate volume represent important parameters in PCa and in high grade disease detection at biopsy, respectively.
AB - OBJECTIVE: To investigate the prostate cancer (PCa) prevalence and risk factors of men with prostate-specific antigen (PSA) level or =7. RESULTS: Overall PCa detection rate was 23.1%. The majority had a biopsy Gleason sum of 6 (79.5%) and 20.5% had a biopsy Gleason sum> or =7. Total PSA (tPSA) and percentage of free PSA (%fPSA) were statistically significantly different in men with and without PCa (all p or = 7 at biopsy, %fPSA and prostate volume represented independent and most informative risk factors. CONCLUSION: Our data demonstrate that a substantial percentage (23.1%) of men with a PSA<or =4.0 ng/ml and an unsuspicious DRE in a biopsy referral population harbor PCa, with 20.5% being high grade. Low %fPSA and low prostate volume represent important parameters in PCa and in high grade disease detection at biopsy, respectively.
M3 - SCORING: Zeitschriftenaufsatz
VL - 53
SP - 750
EP - 757
JO - EUR UROL
JF - EUR UROL
SN - 0302-2838
IS - 4
M1 - 4
ER -