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Conceptual framework for precision cancer medicine in Germany: Consensus statement of the Deutsche Krebshilfe working group 'Molecular Diagnostics and Therapy'

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Conceptual framework for precision cancer medicine in Germany: Consensus statement of the Deutsche Krebshilfe working group 'Molecular Diagnostics and Therapy'. / Westphalen, Benedikt C; Bokemeyer, Carsten; Büttner, Reinhard; Fröhling, Stefan; Gaidzik, Verena I; Glimm, Hanno; Hacker, Ulrich T; Heinemann, Volker; Illert, Anna L; Keilholz, Ulrich; Kindler, Thomas; Kirschner, Martin; Schilling, Bastian; Siveke, Jens T; Schroeder, Thomas; Tischler, Verena; Wagner, Sebastian; Weichert, Wilko; Zips, Daniel; Loges, Sonja; Working Group Molecular Diagnostics and Therapy.

in: EUR J CANCER, Jahrgang 135, 08.2020, S. 1-7.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung

Harvard

Westphalen, BC, Bokemeyer, C, Büttner, R, Fröhling, S, Gaidzik, VI, Glimm, H, Hacker, UT, Heinemann, V, Illert, AL, Keilholz, U, Kindler, T, Kirschner, M, Schilling, B, Siveke, JT, Schroeder, T, Tischler, V, Wagner, S, Weichert, W, Zips, D, Loges, S & Working Group Molecular Diagnostics and Therapy 2020, 'Conceptual framework for precision cancer medicine in Germany: Consensus statement of the Deutsche Krebshilfe working group 'Molecular Diagnostics and Therapy'', EUR J CANCER, Jg. 135, S. 1-7. https://doi.org/10.1016/j.ejca.2020.04.019

APA

Westphalen, B. C., Bokemeyer, C., Büttner, R., Fröhling, S., Gaidzik, V. I., Glimm, H., Hacker, U. T., Heinemann, V., Illert, A. L., Keilholz, U., Kindler, T., Kirschner, M., Schilling, B., Siveke, J. T., Schroeder, T., Tischler, V., Wagner, S., Weichert, W., Zips, D., ... Working Group Molecular Diagnostics and Therapy (2020). Conceptual framework for precision cancer medicine in Germany: Consensus statement of the Deutsche Krebshilfe working group 'Molecular Diagnostics and Therapy'. EUR J CANCER, 135, 1-7. https://doi.org/10.1016/j.ejca.2020.04.019

Vancouver

Westphalen BC, Bokemeyer C, Büttner R, Fröhling S, Gaidzik VI, Glimm H et al. Conceptual framework for precision cancer medicine in Germany: Consensus statement of the Deutsche Krebshilfe working group 'Molecular Diagnostics and Therapy'. EUR J CANCER. 2020 Aug;135:1-7. https://doi.org/10.1016/j.ejca.2020.04.019

Bibtex

@article{d97a9783f96d424a8fad6d0f7f3a853a,
title = "Conceptual framework for precision cancer medicine in Germany: Consensus statement of the Deutsche Krebshilfe working group 'Molecular Diagnostics and Therapy'",
abstract = "Precision cancer medicine (PCM) holds great promises to offer more effective therapies to patients based on molecular profiling of their individual tumours. Although the PCM approach seems intuitive, multiple conceptional and structural challenges interfere with the broad implementation of PCM into clinical practice. Accordingly, concerted national and international efforts are needed to guide the further development and broad adoption of PCM in Germany. With support of the 'German Cancer Aid' (Deutsche Krebshilfe [DKH]) a task force 'Molecular Diagnostics and Therapy' was implemented. In two workshops supported by the DKH, delegates from the fourteen comprehensive cancer centresidentified key topics essential to implement quality-guided, harmonized and adaptable PCM. Based on an online questionnaire and using a modified Delphi approach, nine statements were drafted and evaluated within the group. These statements could serve as a basis to define a collaborative strategy for PCM in the future with the aim to sustain and further improve its quality.",
author = "Westphalen, {Benedikt C} and Carsten Bokemeyer and Reinhard B{\"u}ttner and Stefan Fr{\"o}hling and Gaidzik, {Verena I} and Hanno Glimm and Hacker, {Ulrich T} and Volker Heinemann and Illert, {Anna L} and Ulrich Keilholz and Thomas Kindler and Martin Kirschner and Bastian Schilling and Siveke, {Jens T} and Thomas Schroeder and Verena Tischler and Sebastian Wagner and Wilko Weichert and Daniel Zips and Sonja Loges and {Working Group Molecular Diagnostics and Therapy}",
note = "Copyright {\textcopyright} 2020 Elsevier Ltd. All rights reserved.",
year = "2020",
month = aug,
doi = "10.1016/j.ejca.2020.04.019",
language = "English",
volume = "135",
pages = "1--7",
journal = "EUR J CANCER",
issn = "0959-8049",
publisher = "Elsevier Limited",

}

RIS

TY - JOUR

T1 - Conceptual framework for precision cancer medicine in Germany: Consensus statement of the Deutsche Krebshilfe working group 'Molecular Diagnostics and Therapy'

AU - Westphalen, Benedikt C

AU - Bokemeyer, Carsten

AU - Büttner, Reinhard

AU - Fröhling, Stefan

AU - Gaidzik, Verena I

AU - Glimm, Hanno

AU - Hacker, Ulrich T

AU - Heinemann, Volker

AU - Illert, Anna L

AU - Keilholz, Ulrich

AU - Kindler, Thomas

AU - Kirschner, Martin

AU - Schilling, Bastian

AU - Siveke, Jens T

AU - Schroeder, Thomas

AU - Tischler, Verena

AU - Wagner, Sebastian

AU - Weichert, Wilko

AU - Zips, Daniel

AU - Loges, Sonja

AU - Working Group Molecular Diagnostics and Therapy

N1 - Copyright © 2020 Elsevier Ltd. All rights reserved.

PY - 2020/8

Y1 - 2020/8

N2 - Precision cancer medicine (PCM) holds great promises to offer more effective therapies to patients based on molecular profiling of their individual tumours. Although the PCM approach seems intuitive, multiple conceptional and structural challenges interfere with the broad implementation of PCM into clinical practice. Accordingly, concerted national and international efforts are needed to guide the further development and broad adoption of PCM in Germany. With support of the 'German Cancer Aid' (Deutsche Krebshilfe [DKH]) a task force 'Molecular Diagnostics and Therapy' was implemented. In two workshops supported by the DKH, delegates from the fourteen comprehensive cancer centresidentified key topics essential to implement quality-guided, harmonized and adaptable PCM. Based on an online questionnaire and using a modified Delphi approach, nine statements were drafted and evaluated within the group. These statements could serve as a basis to define a collaborative strategy for PCM in the future with the aim to sustain and further improve its quality.

AB - Precision cancer medicine (PCM) holds great promises to offer more effective therapies to patients based on molecular profiling of their individual tumours. Although the PCM approach seems intuitive, multiple conceptional and structural challenges interfere with the broad implementation of PCM into clinical practice. Accordingly, concerted national and international efforts are needed to guide the further development and broad adoption of PCM in Germany. With support of the 'German Cancer Aid' (Deutsche Krebshilfe [DKH]) a task force 'Molecular Diagnostics and Therapy' was implemented. In two workshops supported by the DKH, delegates from the fourteen comprehensive cancer centresidentified key topics essential to implement quality-guided, harmonized and adaptable PCM. Based on an online questionnaire and using a modified Delphi approach, nine statements were drafted and evaluated within the group. These statements could serve as a basis to define a collaborative strategy for PCM in the future with the aim to sustain and further improve its quality.

U2 - 10.1016/j.ejca.2020.04.019

DO - 10.1016/j.ejca.2020.04.019

M3 - SCORING: Review article

C2 - 32521293

VL - 135

SP - 1

EP - 7

JO - EUR J CANCER

JF - EUR J CANCER

SN - 0959-8049

ER -