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Comparison of microarray-based RNA expression with ELISA-based protein determination of HER2, uPA and PAI-1 in tumour tissue of patients with breast cancer and relation to outcome.

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Comparison of microarray-based RNA expression with ELISA-based protein determination of HER2, uPA and PAI-1 in tumour tissue of patients with breast cancer and relation to outcome. / Witzel, Isabell; Milde-Langosch, Karin; Wirtz, Ralph M; Roth, Claudia; Henningsen, Maike; Mahner, Sven; Zu Eulenburg, Christine Gräfin; Jänicke, Fritz; Müller, Volkmar.

in: J CANCER RES CLIN, Jahrgang 136, Nr. 11, 11, 2010, S. 1709-1718.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Witzel, I, Milde-Langosch, K, Wirtz, RM, Roth, C, Henningsen, M, Mahner, S, Zu Eulenburg, CG, Jänicke, F & Müller, V 2010, 'Comparison of microarray-based RNA expression with ELISA-based protein determination of HER2, uPA and PAI-1 in tumour tissue of patients with breast cancer and relation to outcome.', J CANCER RES CLIN, Jg. 136, Nr. 11, 11, S. 1709-1718. <http://www.ncbi.nlm.nih.gov/pubmed/20204407?dopt=Citation>

APA

Witzel, I., Milde-Langosch, K., Wirtz, R. M., Roth, C., Henningsen, M., Mahner, S., Zu Eulenburg, C. G., Jänicke, F., & Müller, V. (2010). Comparison of microarray-based RNA expression with ELISA-based protein determination of HER2, uPA and PAI-1 in tumour tissue of patients with breast cancer and relation to outcome. J CANCER RES CLIN, 136(11), 1709-1718. [11]. http://www.ncbi.nlm.nih.gov/pubmed/20204407?dopt=Citation

Vancouver

Witzel I, Milde-Langosch K, Wirtz RM, Roth C, Henningsen M, Mahner S et al. Comparison of microarray-based RNA expression with ELISA-based protein determination of HER2, uPA and PAI-1 in tumour tissue of patients with breast cancer and relation to outcome. J CANCER RES CLIN. 2010;136(11):1709-1718. 11.

Bibtex

@article{e9b35ca14a5a4cbb947ac6838a11972a,
title = "Comparison of microarray-based RNA expression with ELISA-based protein determination of HER2, uPA and PAI-1 in tumour tissue of patients with breast cancer and relation to outcome.",
abstract = "Prognostic and predictive markers in breast cancer are currently determined by single analysis of protein amounts. If RNA-based multi-gene analyses enter clinical practice, simultaneous determination of currently established markers like human epidermal growth factor receptor 2 (HER2), urokinase plasminogen activator (uPA) and its inhibitor (PAI-1) would represent an elegant simplification. To investigate the correlation between RNA and protein levels, we assessed HER2, uPA and PAI-1 in patients with breast cancer. In addition, we evaluated the influence of these factors on patient outcome.",
author = "Isabell Witzel and Karin Milde-Langosch and Wirtz, {Ralph M} and Claudia Roth and Maike Henningsen and Sven Mahner and {Zu Eulenburg}, {Christine Gr{\"a}fin} and Fritz J{\"a}nicke and Volkmar M{\"u}ller",
year = "2010",
language = "Deutsch",
volume = "136",
pages = "1709--1718",
journal = "J CANCER RES CLIN",
issn = "0171-5216",
publisher = "Springer",
number = "11",

}

RIS

TY - JOUR

T1 - Comparison of microarray-based RNA expression with ELISA-based protein determination of HER2, uPA and PAI-1 in tumour tissue of patients with breast cancer and relation to outcome.

AU - Witzel, Isabell

AU - Milde-Langosch, Karin

AU - Wirtz, Ralph M

AU - Roth, Claudia

AU - Henningsen, Maike

AU - Mahner, Sven

AU - Zu Eulenburg, Christine Gräfin

AU - Jänicke, Fritz

AU - Müller, Volkmar

PY - 2010

Y1 - 2010

N2 - Prognostic and predictive markers in breast cancer are currently determined by single analysis of protein amounts. If RNA-based multi-gene analyses enter clinical practice, simultaneous determination of currently established markers like human epidermal growth factor receptor 2 (HER2), urokinase plasminogen activator (uPA) and its inhibitor (PAI-1) would represent an elegant simplification. To investigate the correlation between RNA and protein levels, we assessed HER2, uPA and PAI-1 in patients with breast cancer. In addition, we evaluated the influence of these factors on patient outcome.

AB - Prognostic and predictive markers in breast cancer are currently determined by single analysis of protein amounts. If RNA-based multi-gene analyses enter clinical practice, simultaneous determination of currently established markers like human epidermal growth factor receptor 2 (HER2), urokinase plasminogen activator (uPA) and its inhibitor (PAI-1) would represent an elegant simplification. To investigate the correlation between RNA and protein levels, we assessed HER2, uPA and PAI-1 in patients with breast cancer. In addition, we evaluated the influence of these factors on patient outcome.

M3 - SCORING: Zeitschriftenaufsatz

VL - 136

SP - 1709

EP - 1718

JO - J CANCER RES CLIN

JF - J CANCER RES CLIN

SN - 0171-5216

IS - 11

M1 - 11

ER -