Comparison of genetic and clinical aspects in patients with acute myeloid leukemia and myelodysplastic syndromes all with more than 50% of bone marrow erythropoietic cells.
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Comparison of genetic and clinical aspects in patients with acute myeloid leukemia and myelodysplastic syndromes all with more than 50% of bone marrow erythropoietic cells. / Bacher, Ulrike; Haferlach, Claudia; Alpermann, Tamara; Kern, Wolfgang; Schnittger, Susanne; Haferlach, Torsten.
in: HAEMATOLOGICA, Jahrgang 96, Nr. 9, 9, 2011, S. 1284-1292.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Comparison of genetic and clinical aspects in patients with acute myeloid leukemia and myelodysplastic syndromes all with more than 50% of bone marrow erythropoietic cells.
AU - Bacher, Ulrike
AU - Haferlach, Claudia
AU - Alpermann, Tamara
AU - Kern, Wolfgang
AU - Schnittger, Susanne
AU - Haferlach, Torsten
PY - 2011
Y1 - 2011
N2 - The World Health Organization separates acute erythroid leukemia (erythropoiesis in ?50% of nucleated bone marrow cells; ?20% myeloblasts of non-erythroid cells) from other entities with increased erythropoiesis - acute myeloid leukemia with myelodysplasia-related changes (?20% myeloblasts of all nucleated cells) or myelodysplastic syndromes - and subdivides acute erythroid leukemia into erythroleukemia and pure erythroid leukemia subtypes. We aimed to investigate the biological/genetic justification for the different categories of myeloid malignancies with increased erythropoiesis (?50% of bone marrow cells).
AB - The World Health Organization separates acute erythroid leukemia (erythropoiesis in ?50% of nucleated bone marrow cells; ?20% myeloblasts of non-erythroid cells) from other entities with increased erythropoiesis - acute myeloid leukemia with myelodysplasia-related changes (?20% myeloblasts of all nucleated cells) or myelodysplastic syndromes - and subdivides acute erythroid leukemia into erythroleukemia and pure erythroid leukemia subtypes. We aimed to investigate the biological/genetic justification for the different categories of myeloid malignancies with increased erythropoiesis (?50% of bone marrow cells).
KW - Adult
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Aged, 80 and over
KW - Adolescent
KW - Young Adult
KW - Immunophenotyping
KW - Kaplan-Meier Estimate
KW - Mutation/genetics
KW - Nuclear Proteins/genetics
KW - Bone Marrow Cells/pathology
KW - Cytogenetic Analysis
KW - Erythroid Cells/pathology
KW - Erythropoiesis
KW - Leukemia, Myeloid, Acute/classification/genetics/mortality/pathology
KW - Myelodysplastic Syndromes/classification/genetics/mortality/pathology
KW - Oncogene Proteins, Fusion/genetics
KW - Adult
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Aged, 80 and over
KW - Adolescent
KW - Young Adult
KW - Immunophenotyping
KW - Kaplan-Meier Estimate
KW - Mutation/genetics
KW - Nuclear Proteins/genetics
KW - Bone Marrow Cells/pathology
KW - Cytogenetic Analysis
KW - Erythroid Cells/pathology
KW - Erythropoiesis
KW - Leukemia, Myeloid, Acute/classification/genetics/mortality/pathology
KW - Myelodysplastic Syndromes/classification/genetics/mortality/pathology
KW - Oncogene Proteins, Fusion/genetics
U2 - 10.3324/haematol.2011.043687
DO - 10.3324/haematol.2011.043687
M3 - SCORING: Journal article
VL - 96
SP - 1284
EP - 1292
JO - HAEMATOLOGICA
JF - HAEMATOLOGICA
SN - 0390-6078
IS - 9
M1 - 9
ER -
