Comparative examination of the stability of semiconductor quantum dots in various biochemical buffers.
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Comparative examination of the stability of semiconductor quantum dots in various biochemical buffers. / Boldt, Klaus; Bruns, Oliver; Gaponik, Nikolai; Eychmüller, Alexander.
in: J PHYS CHEM B, Jahrgang 110, Nr. 5, 5, 2006, S. 1959-1963.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Comparative examination of the stability of semiconductor quantum dots in various biochemical buffers.
AU - Boldt, Klaus
AU - Bruns, Oliver
AU - Gaponik, Nikolai
AU - Eychmüller, Alexander
PY - 2006
Y1 - 2006
N2 - Due to their greater photostability compared to established organic fluorescence markers, semiconductor quantum dots provide an attractive alternative for the biolabeling of living cells. On the basis of a comparative investigation using differently sized thiol-stabilized CdTe nanocrystals in a variety of commonly used biological buffers, a method is developed to quantify the stability of such a multicomponent system. Above a certain critical size, the intensity of the photoluminescence of the nanocrystals is found to diminish with pseudo-zero-order kinetics, whereas for specific combinations of particle size, ligand, and buffer there appears to be no decay below this critical particle size, pointing out the necessity for thorough investigations of this kind in the view of prospect applications of semiconductor nanocrystals in the area of biolabeling.
AB - Due to their greater photostability compared to established organic fluorescence markers, semiconductor quantum dots provide an attractive alternative for the biolabeling of living cells. On the basis of a comparative investigation using differently sized thiol-stabilized CdTe nanocrystals in a variety of commonly used biological buffers, a method is developed to quantify the stability of such a multicomponent system. Above a certain critical size, the intensity of the photoluminescence of the nanocrystals is found to diminish with pseudo-zero-order kinetics, whereas for specific combinations of particle size, ligand, and buffer there appears to be no decay below this critical particle size, pointing out the necessity for thorough investigations of this kind in the view of prospect applications of semiconductor nanocrystals in the area of biolabeling.
M3 - SCORING: Zeitschriftenaufsatz
VL - 110
SP - 1959
EP - 1963
JO - J PHYS CHEM B
JF - J PHYS CHEM B
SN - 1520-6106
IS - 5
M1 - 5
ER -