Comorbid depression in medical diseases
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Comorbid depression in medical diseases. / Gold, Stefan M; Köhler-Forsberg, Ole; Moss-Morris, Rona; Mehnert, Anja; Miranda, J Jaime; Bullinger, Monika; Steptoe, Andrew; Whooley, Mary A; Otte, Christian.
in: NAT REV DIS PRIMERS, Jahrgang 6, Nr. 1, 20.08.2020, S. 69.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung
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TY - JOUR
T1 - Comorbid depression in medical diseases
AU - Gold, Stefan M
AU - Köhler-Forsberg, Ole
AU - Moss-Morris, Rona
AU - Mehnert, Anja
AU - Miranda, J Jaime
AU - Bullinger, Monika
AU - Steptoe, Andrew
AU - Whooley, Mary A
AU - Otte, Christian
PY - 2020/8/20
Y1 - 2020/8/20
N2 - Depression is one of the most common comorbidities of many chronic medical diseases including cancer and cardiovascular, metabolic, inflammatory and neurological disorders. Indeed, the prevalence of depression in these patient groups is often substantially higher than in the general population, and depression accounts for a substantial part of the psychosocial burden of these disorders. Many factors can contribute to the occurrence of comorbid depression, such as shared genetic factors, converging biological pathways, social factors, health behaviours and psychological factors. Diagnosis of depression in patients with a medical disorder can be particularly challenging owing to symptomatic overlap. Although pharmacological and psychological treatments can be effective, adjustments may need to be made for patients with a comorbid medical disorder. In addition, symptoms or treatments of medical disorders may interfere with the treatment of depression. Conversely, symptoms of depression may decrease adherence to treatment of both disorders. Thus, comprehensive treatment plans are necessary to optimize care.
AB - Depression is one of the most common comorbidities of many chronic medical diseases including cancer and cardiovascular, metabolic, inflammatory and neurological disorders. Indeed, the prevalence of depression in these patient groups is often substantially higher than in the general population, and depression accounts for a substantial part of the psychosocial burden of these disorders. Many factors can contribute to the occurrence of comorbid depression, such as shared genetic factors, converging biological pathways, social factors, health behaviours and psychological factors. Diagnosis of depression in patients with a medical disorder can be particularly challenging owing to symptomatic overlap. Although pharmacological and psychological treatments can be effective, adjustments may need to be made for patients with a comorbid medical disorder. In addition, symptoms or treatments of medical disorders may interfere with the treatment of depression. Conversely, symptoms of depression may decrease adherence to treatment of both disorders. Thus, comprehensive treatment plans are necessary to optimize care.
U2 - 10.1038/s41572-020-0200-2
DO - 10.1038/s41572-020-0200-2
M3 - SCORING: Review article
C2 - 32820163
VL - 6
SP - 69
JO - NAT REV DIS PRIMERS
JF - NAT REV DIS PRIMERS
SN - 2056-676X
IS - 1
ER -