Community acquired respiratory virus infections in cancer patients-Guideline on diagnosis and management by the Infectious Diseases Working Party of the German Society for haematology and Medical Oncology

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Community acquired respiratory virus infections in cancer patients-Guideline on diagnosis and management by the Infectious Diseases Working Party of the German Society for haematology and Medical Oncology. / von Lilienfeld-Toal, Marie; Berger, Annemarie; Christopeit, Maximilian; Hentrich, Marcus; Heussel, Claus Peter; Kalkreuth, Jana; Klein, Michael; Kochanek, Matthias; Penack, Olaf; Hauf, Elke; Rieger, Christina; Silling, Gerda; Vehreschild, Maria; Weber, Thomas; Wolf, Hans-Heinrich; Lehners, Nicola; Schalk, Enrico; Mayer, Karin.

in: EUR J CANCER, Jahrgang 67, 11.2016, S. 200-212.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

Harvard

von Lilienfeld-Toal, M, Berger, A, Christopeit, M, Hentrich, M, Heussel, CP, Kalkreuth, J, Klein, M, Kochanek, M, Penack, O, Hauf, E, Rieger, C, Silling, G, Vehreschild, M, Weber, T, Wolf, H-H, Lehners, N, Schalk, E & Mayer, K 2016, 'Community acquired respiratory virus infections in cancer patients-Guideline on diagnosis and management by the Infectious Diseases Working Party of the German Society for haematology and Medical Oncology', EUR J CANCER, Jg. 67, S. 200-212. https://doi.org/10.1016/j.ejca.2016.08.015

APA

von Lilienfeld-Toal, M., Berger, A., Christopeit, M., Hentrich, M., Heussel, C. P., Kalkreuth, J., Klein, M., Kochanek, M., Penack, O., Hauf, E., Rieger, C., Silling, G., Vehreschild, M., Weber, T., Wolf, H-H., Lehners, N., Schalk, E., & Mayer, K. (2016). Community acquired respiratory virus infections in cancer patients-Guideline on diagnosis and management by the Infectious Diseases Working Party of the German Society for haematology and Medical Oncology. EUR J CANCER, 67, 200-212. https://doi.org/10.1016/j.ejca.2016.08.015

Vancouver

Bibtex

@article{bd654afca8c34dc8b5e1cc654498bd5e,
title = "Community acquired respiratory virus infections in cancer patients-Guideline on diagnosis and management by the Infectious Diseases Working Party of the German Society for haematology and Medical Oncology",
abstract = "BACKGROUND: Community acquired viruses (CRVs) may cause severe disease in cancer patients. Thus, efforts should be made to diagnose CRV rapidly and manage CRV infections accordingly.METHODS: A panel of 18 clinicians from the Infectious Diseases Working Party of the German Society for Haematology and Medical Oncology have convened to assess the available literature and provide recommendations on the management of CRV infections including influenza, respiratory syncytial virus, parainfluenza virus, human metapneumovirus and adenovirus.RESULTS: CRV infections in cancer patients may lead to pneumonia in approximately 30% of the cases, with an associated mortality of around 25%. For diagnosis of a CRV infection, combined nasal/throat swabs or washes/aspirates give the best results and nucleic acid amplification based-techniques (NAT) should be used to detect the pathogen. Hand hygiene, contact isolation and face masks have been shown to be of benefit as general infection management. Causal treatment can be given for influenza, using a neuraminidase inhibitor, and respiratory syncytial virus, using ribavirin in addition to intravenous immunoglobulins. Ribavirin has also been used to treat parainfluenza virus and human metapneumovirus, but data are inconclusive in this setting. Cidofovir is used to treat adenovirus pneumonitis.CONCLUSIONS: CRV infections may pose a vital threat to patients with underlying malignancy. This guideline provides information on diagnosis and treatment to improve the outcome.",
author = "{von Lilienfeld-Toal}, Marie and Annemarie Berger and Maximilian Christopeit and Marcus Hentrich and Heussel, {Claus Peter} and Jana Kalkreuth and Michael Klein and Matthias Kochanek and Olaf Penack and Elke Hauf and Christina Rieger and Gerda Silling and Maria Vehreschild and Thomas Weber and Hans-Heinrich Wolf and Nicola Lehners and Enrico Schalk and Karin Mayer",
note = "Copyright {\textcopyright} 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.",
year = "2016",
month = nov,
doi = "10.1016/j.ejca.2016.08.015",
language = "English",
volume = "67",
pages = "200--212",
journal = "EUR J CANCER",
issn = "0959-8049",
publisher = "Elsevier Limited",

}

RIS

TY - JOUR

T1 - Community acquired respiratory virus infections in cancer patients-Guideline on diagnosis and management by the Infectious Diseases Working Party of the German Society for haematology and Medical Oncology

AU - von Lilienfeld-Toal, Marie

AU - Berger, Annemarie

AU - Christopeit, Maximilian

AU - Hentrich, Marcus

AU - Heussel, Claus Peter

AU - Kalkreuth, Jana

AU - Klein, Michael

AU - Kochanek, Matthias

AU - Penack, Olaf

AU - Hauf, Elke

AU - Rieger, Christina

AU - Silling, Gerda

AU - Vehreschild, Maria

AU - Weber, Thomas

AU - Wolf, Hans-Heinrich

AU - Lehners, Nicola

AU - Schalk, Enrico

AU - Mayer, Karin

N1 - Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

PY - 2016/11

Y1 - 2016/11

N2 - BACKGROUND: Community acquired viruses (CRVs) may cause severe disease in cancer patients. Thus, efforts should be made to diagnose CRV rapidly and manage CRV infections accordingly.METHODS: A panel of 18 clinicians from the Infectious Diseases Working Party of the German Society for Haematology and Medical Oncology have convened to assess the available literature and provide recommendations on the management of CRV infections including influenza, respiratory syncytial virus, parainfluenza virus, human metapneumovirus and adenovirus.RESULTS: CRV infections in cancer patients may lead to pneumonia in approximately 30% of the cases, with an associated mortality of around 25%. For diagnosis of a CRV infection, combined nasal/throat swabs or washes/aspirates give the best results and nucleic acid amplification based-techniques (NAT) should be used to detect the pathogen. Hand hygiene, contact isolation and face masks have been shown to be of benefit as general infection management. Causal treatment can be given for influenza, using a neuraminidase inhibitor, and respiratory syncytial virus, using ribavirin in addition to intravenous immunoglobulins. Ribavirin has also been used to treat parainfluenza virus and human metapneumovirus, but data are inconclusive in this setting. Cidofovir is used to treat adenovirus pneumonitis.CONCLUSIONS: CRV infections may pose a vital threat to patients with underlying malignancy. This guideline provides information on diagnosis and treatment to improve the outcome.

AB - BACKGROUND: Community acquired viruses (CRVs) may cause severe disease in cancer patients. Thus, efforts should be made to diagnose CRV rapidly and manage CRV infections accordingly.METHODS: A panel of 18 clinicians from the Infectious Diseases Working Party of the German Society for Haematology and Medical Oncology have convened to assess the available literature and provide recommendations on the management of CRV infections including influenza, respiratory syncytial virus, parainfluenza virus, human metapneumovirus and adenovirus.RESULTS: CRV infections in cancer patients may lead to pneumonia in approximately 30% of the cases, with an associated mortality of around 25%. For diagnosis of a CRV infection, combined nasal/throat swabs or washes/aspirates give the best results and nucleic acid amplification based-techniques (NAT) should be used to detect the pathogen. Hand hygiene, contact isolation and face masks have been shown to be of benefit as general infection management. Causal treatment can be given for influenza, using a neuraminidase inhibitor, and respiratory syncytial virus, using ribavirin in addition to intravenous immunoglobulins. Ribavirin has also been used to treat parainfluenza virus and human metapneumovirus, but data are inconclusive in this setting. Cidofovir is used to treat adenovirus pneumonitis.CONCLUSIONS: CRV infections may pose a vital threat to patients with underlying malignancy. This guideline provides information on diagnosis and treatment to improve the outcome.

U2 - 10.1016/j.ejca.2016.08.015

DO - 10.1016/j.ejca.2016.08.015

M3 - SCORING: Journal article

C2 - 27681877

VL - 67

SP - 200

EP - 212

JO - EUR J CANCER

JF - EUR J CANCER

SN - 0959-8049

ER -