Combined T2*-weighted measurements of the human brain and cervical spinal cord with a dynamic shim update

Jürgen Finsterbusch; Christian Sprenger; Christian Büchel

doi:10.1016/j.neuroimage.2013.04.021

Combined T2*-weighted measurements of the human brain and cervical spinal cord with a dynamic shim update

Standard

Combined T2*-weighted measurements of the human brain and cervical spinal cord with a dynamic shim update. / Finsterbusch, Jürgen ; Sprenger, Christian ; Büchel, Christian.

in: NEUROIMAGE, Jahrgang 79, 01.10.2013, S. 153-61.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Finsterbusch, J , Sprenger, C & Büchel, C 2013, 'Combined T2*-weighted measurements of the human brain and cervical spinal cord with a dynamic shim update', NEUROIMAGE, Jg. 79, S. 153-61. https://doi.org/10.1016/j.neuroimage.2013.04.021

APA

Finsterbusch, J., Sprenger, C., & Büchel, C. (2013). Combined T2*-weighted measurements of the human brain and cervical spinal cord with a dynamic shim update. NEUROIMAGE, 79, 153-61. https://doi.org/10.1016/j.neuroimage.2013.04.021

Vancouver

Finsterbusch J , Sprenger C , Büchel C. Combined T2*-weighted measurements of the human brain and cervical spinal cord with a dynamic shim update. NEUROIMAGE. 2013 Okt 1;79:153-61. https://doi.org/10.1016/j.neuroimage.2013.04.021

Bibtex

@article{21bfdfe013b64ef4904edae36fb5c514,

title = "Combined T2*-weighted measurements of the human brain and cervical spinal cord with a dynamic shim update",

abstract = "Important functions of the central nervous system such as sensory processing and motor execution, involve the spinal cord. Recent advances in human functional MRI have allowed to investigate spinal cord neuronal processes using the blood-oxygenation-level-dependent (BOLD) contrast. However, to assess the functional connectivity between the brain and the spinal cord, functional MRI measurements covering both regions in the same experiment are required. Unfortunately, the ideal MRI setup differs considerably for the brain and the spinal cord with respect to resolution, field-of-view, relevant receive coils, and, in particular, shim adjustments required to minimize distortion artifacts. Here, these issues are addressed for combined T2*-weighted MRI measurements of the human brain and the cervical spinal cord by using adapted parameter settings (field-of-view, in-plane resolution, slice thickness, and receiver bandwidth) for each region, a dynamic receive coil element selection where for each slice only the elements with significant signal contributions are considered, and, most importantly, the implementation of a dynamic update of the frequency and the linear shims in order to provide shim settings individually adapted to the brain and spinal cord subvolume. The feasibility of this setup for combined measurements is demonstrated in healthy volunteers at 3T. Although geometric distortions are slightly more pronounced and the temporal signal-to-noise ratio is lower as compared to measurements focusing to the brain or spinal cord only, the overall image quality can be expected to be sufficient for combined functional MRI experiments. Thus, the presented approach could help to unravel the functional coupling between the brain and the spinal cord.",

keywords = "Algorithms, Brain, Cervical Vertebrae, Humans, Image Enhancement, Image Interpretation, Computer-Assisted, Magnetic Resonance Imaging, Reproducibility of Results, Sensitivity and Specificity, Spinal Cord",

author = "J{\"u}rgen Finsterbusch and Christian Sprenger and Christian B{\"u}chel",

year = "2013",

month = oct,

day = "1",

doi = "10.1016/j.neuroimage.2013.04.021",

language = "English",

volume = "79",

pages = "153--61",

journal = "NEUROIMAGE",

issn = "1053-8119",

publisher = "Academic Press",

}

RIS

TY - JOUR

T1 - Combined T2*-weighted measurements of the human brain and cervical spinal cord with a dynamic shim update

AU - Finsterbusch, Jürgen

AU - Sprenger, Christian

AU - Büchel, Christian

PY - 2013/10/1

Y1 - 2013/10/1

N2 - Important functions of the central nervous system such as sensory processing and motor execution, involve the spinal cord. Recent advances in human functional MRI have allowed to investigate spinal cord neuronal processes using the blood-oxygenation-level-dependent (BOLD) contrast. However, to assess the functional connectivity between the brain and the spinal cord, functional MRI measurements covering both regions in the same experiment are required. Unfortunately, the ideal MRI setup differs considerably for the brain and the spinal cord with respect to resolution, field-of-view, relevant receive coils, and, in particular, shim adjustments required to minimize distortion artifacts. Here, these issues are addressed for combined T2*-weighted MRI measurements of the human brain and the cervical spinal cord by using adapted parameter settings (field-of-view, in-plane resolution, slice thickness, and receiver bandwidth) for each region, a dynamic receive coil element selection where for each slice only the elements with significant signal contributions are considered, and, most importantly, the implementation of a dynamic update of the frequency and the linear shims in order to provide shim settings individually adapted to the brain and spinal cord subvolume. The feasibility of this setup for combined measurements is demonstrated in healthy volunteers at 3T. Although geometric distortions are slightly more pronounced and the temporal signal-to-noise ratio is lower as compared to measurements focusing to the brain or spinal cord only, the overall image quality can be expected to be sufficient for combined functional MRI experiments. Thus, the presented approach could help to unravel the functional coupling between the brain and the spinal cord.

AB - Important functions of the central nervous system such as sensory processing and motor execution, involve the spinal cord. Recent advances in human functional MRI have allowed to investigate spinal cord neuronal processes using the blood-oxygenation-level-dependent (BOLD) contrast. However, to assess the functional connectivity between the brain and the spinal cord, functional MRI measurements covering both regions in the same experiment are required. Unfortunately, the ideal MRI setup differs considerably for the brain and the spinal cord with respect to resolution, field-of-view, relevant receive coils, and, in particular, shim adjustments required to minimize distortion artifacts. Here, these issues are addressed for combined T2*-weighted MRI measurements of the human brain and the cervical spinal cord by using adapted parameter settings (field-of-view, in-plane resolution, slice thickness, and receiver bandwidth) for each region, a dynamic receive coil element selection where for each slice only the elements with significant signal contributions are considered, and, most importantly, the implementation of a dynamic update of the frequency and the linear shims in order to provide shim settings individually adapted to the brain and spinal cord subvolume. The feasibility of this setup for combined measurements is demonstrated in healthy volunteers at 3T. Although geometric distortions are slightly more pronounced and the temporal signal-to-noise ratio is lower as compared to measurements focusing to the brain or spinal cord only, the overall image quality can be expected to be sufficient for combined functional MRI experiments. Thus, the presented approach could help to unravel the functional coupling between the brain and the spinal cord.

KW - Algorithms

KW - Brain

KW - Cervical Vertebrae

KW - Humans

KW - Image Enhancement

KW - Image Interpretation, Computer-Assisted

KW - Magnetic Resonance Imaging

KW - Reproducibility of Results

KW - Sensitivity and Specificity

KW - Spinal Cord

U2 - 10.1016/j.neuroimage.2013.04.021

DO - 10.1016/j.neuroimage.2013.04.021

M3 - SCORING: Journal article

C2 - 23603283

VL - 79

SP - 153

EP - 161

JO - NEUROIMAGE

JF - NEUROIMAGE

SN - 1053-8119

ER -