PortalPublikationenCognitive performance before and after the onset of subjecti...

Cognitive performance before and after the onset of subjective cognitive decline in old age

Standard

Cognitive performance before and after the onset of subjective cognitive decline in old age. / Koppara, Alexander; Wagner, Michael; Lange, Carolin; Ernst, Annette; Wiese, Birgitt; König, Hans-Helmut; Brettschneider, Christian; Riedel-Heller, Steffi; Luppa, Melanie; Weyerer, Siegfried; Werle, Jochen; Bickel, Horst; Mösch, Edelgard; Pentzek, Michael; Fuchs, Angela; Wolfsgruber, Steffen; Beauducel, André; Scherer, Martin; Maier, Wolfgang; Jessen, Frank.

in: ALZH DEMENT-DADM, Jahrgang 1, Nr. 2, 06.2015, S. 194-205.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Koppara, A, Wagner, M, Lange, C, Ernst, A, Wiese, B, König, H-H, Brettschneider, C, Riedel-Heller, S, Luppa, M, Weyerer, S, Werle, J, Bickel, H, Mösch, E, Pentzek, M, Fuchs, A, Wolfsgruber, S, Beauducel, A, Scherer, M, Maier, W & Jessen, F 2015, 'Cognitive performance before and after the onset of subjective cognitive decline in old age', ALZH DEMENT-DADM, Jg. 1, Nr. 2, S. 194-205. https://doi.org/10.1016/j.dadm.2015.02.005

APA

Koppara, A., Wagner, M., Lange, C., Ernst, A., Wiese, B., König, H-H., Brettschneider, C., Riedel-Heller, S., Luppa, M., Weyerer, S., Werle, J., Bickel, H., Mösch, E., Pentzek, M., Fuchs, A., Wolfsgruber, S., Beauducel, A., Scherer, M., Maier, W., & Jessen, F. (2015). Cognitive performance before and after the onset of subjective cognitive decline in old age. ALZH DEMENT-DADM, 1(2), 194-205. https://doi.org/10.1016/j.dadm.2015.02.005

Vancouver

Koppara A, Wagner M, Lange C, Ernst A, Wiese B, König H-H et al. Cognitive performance before and after the onset of subjective cognitive decline in old age. ALZH DEMENT-DADM. 2015 Jun;1(2):194-205. https://doi.org/10.1016/j.dadm.2015.02.005

Bibtex

@article{86f0b8083c62411db294671bf86f5e78,
title = "Cognitive performance before and after the onset of subjective cognitive decline in old age",
abstract = "BACKGROUND: Our objectives were (1) to test the association between the report of subjective cognitive decline (SCD) and prospective objective cognitive performance in high age individuals and (2) to study the course of longitudinal cognitive performance before and after the first report of SCD.METHODS: Cognitively normal elderly participants of the German Study on Ageing, Cognition, and Dementia study (N = 2330) with SCD (subjective decline in memory with and without associated concerns) and without SCD at baseline were assessed over 8 years with regard to immediate and delayed verbal recall, verbal fluency, working memory, and global cognition. Baseline performance and cognitive trajectories were compared between groups. In addition, cognitive trajectories before and after the initial report of SCD (incident SCD) were modelled in those without SCD at baseline.RESULTS: Baseline performance in the SCD group was lower and declined more steeply in immediate and delayed verbal recall than in the control group (no SCD at baseline). This effect was more pronounced in the SCD group with concerns. Incident SCD was preceded by decline in immediate and delayed memory and word fluency.CONCLUSIONS: SCD predicts future memory decline. Incident SCD is related to previous cognitive decline. The latter finding supports the concept of SCD indicating first subtle decline in cognitive performance that characterizes preclinical Alzheimer's disease.",
author = "Alexander Koppara and Michael Wagner and Carolin Lange and Annette Ernst and Birgitt Wiese and Hans-Helmut K{\"o}nig and Christian Brettschneider and Steffi Riedel-Heller and Melanie Luppa and Siegfried Weyerer and Jochen Werle and Horst Bickel and Edelgard M{\"o}sch and Michael Pentzek and Angela Fuchs and Steffen Wolfsgruber and Andr{\'e} Beauducel and Martin Scherer and Wolfgang Maier and Frank Jessen",
year = "2015",
month = jun,
doi = "10.1016/j.dadm.2015.02.005",
language = "English",
volume = "1",
pages = "194--205",
journal = "ALZH DEMENT-DADM",
issn = "2352-8729",
publisher = "Elsevier BV",
number = "2",

}

RIS

TY - JOUR

T1 - Cognitive performance before and after the onset of subjective cognitive decline in old age

AU - Koppara, Alexander

AU - Wagner, Michael

AU - Lange, Carolin

AU - Ernst, Annette

AU - Wiese, Birgitt

AU - König, Hans-Helmut

AU - Brettschneider, Christian

AU - Riedel-Heller, Steffi

AU - Luppa, Melanie

AU - Weyerer, Siegfried

AU - Werle, Jochen

AU - Bickel, Horst

AU - Mösch, Edelgard

AU - Pentzek, Michael

AU - Fuchs, Angela

AU - Wolfsgruber, Steffen

AU - Beauducel, André

AU - Scherer, Martin

AU - Maier, Wolfgang

AU - Jessen, Frank

PY - 2015/6

Y1 - 2015/6

N2 - BACKGROUND: Our objectives were (1) to test the association between the report of subjective cognitive decline (SCD) and prospective objective cognitive performance in high age individuals and (2) to study the course of longitudinal cognitive performance before and after the first report of SCD.METHODS: Cognitively normal elderly participants of the German Study on Ageing, Cognition, and Dementia study (N = 2330) with SCD (subjective decline in memory with and without associated concerns) and without SCD at baseline were assessed over 8 years with regard to immediate and delayed verbal recall, verbal fluency, working memory, and global cognition. Baseline performance and cognitive trajectories were compared between groups. In addition, cognitive trajectories before and after the initial report of SCD (incident SCD) were modelled in those without SCD at baseline.RESULTS: Baseline performance in the SCD group was lower and declined more steeply in immediate and delayed verbal recall than in the control group (no SCD at baseline). This effect was more pronounced in the SCD group with concerns. Incident SCD was preceded by decline in immediate and delayed memory and word fluency.CONCLUSIONS: SCD predicts future memory decline. Incident SCD is related to previous cognitive decline. The latter finding supports the concept of SCD indicating first subtle decline in cognitive performance that characterizes preclinical Alzheimer's disease.

AB - BACKGROUND: Our objectives were (1) to test the association between the report of subjective cognitive decline (SCD) and prospective objective cognitive performance in high age individuals and (2) to study the course of longitudinal cognitive performance before and after the first report of SCD.METHODS: Cognitively normal elderly participants of the German Study on Ageing, Cognition, and Dementia study (N = 2330) with SCD (subjective decline in memory with and without associated concerns) and without SCD at baseline were assessed over 8 years with regard to immediate and delayed verbal recall, verbal fluency, working memory, and global cognition. Baseline performance and cognitive trajectories were compared between groups. In addition, cognitive trajectories before and after the initial report of SCD (incident SCD) were modelled in those without SCD at baseline.RESULTS: Baseline performance in the SCD group was lower and declined more steeply in immediate and delayed verbal recall than in the control group (no SCD at baseline). This effect was more pronounced in the SCD group with concerns. Incident SCD was preceded by decline in immediate and delayed memory and word fluency.CONCLUSIONS: SCD predicts future memory decline. Incident SCD is related to previous cognitive decline. The latter finding supports the concept of SCD indicating first subtle decline in cognitive performance that characterizes preclinical Alzheimer's disease.

U2 - 10.1016/j.dadm.2015.02.005

DO - 10.1016/j.dadm.2015.02.005

M3 - SCORING: Journal article

C2 - 27239504

VL - 1

SP - 194

EP - 205

JO - ALZH DEMENT-DADM

JF - ALZH DEMENT-DADM

SN - 2352-8729

IS - 2

ER -