Cognitive behavioural therapy versus supportive therapy for persistent positive symptoms in psychotic disorders: the POSITIVE Study, a multicenter, prospective, single-blind, randomised controlled clinical trial.

  • Stefan Klingberg
  • Andreas Wittorf
  • Christoph Meisner
  • Wolfgang Wölwer
  • Georg Wiedemann
  • Jutta Herrlich
  • Andreas Bechdolf
  • Bernhard W Müller
  • Gudrun Sartory
  • Michael Wagner
  • Tilo Kircher
  • Hans-Helmut König
  • Corinna Engel
  • Gerhard Buchkremer

Abstract

It has been demonstrated that cognitive behavioural therapy (CBT) has a moderate effect on symptom reduction and on general well being of patients suffering from psychosis. However, questions regarding the specific efficacy of CBT, the treatment safety, the cost-effectiveness, and the moderators and mediators of treatment effects are still a major issue. The major objective of this trial is to investigate whether CBT is specifically efficacious in reducing positive symptoms when compared with non-specific supportive therapy (ST) which does not implement CBT-techniques but provides comparable therapeutic attention.

Bibliografische Daten

OriginalspracheDeutsch
ISSN1745-6215
DOIs
StatusVeröffentlicht - 2010
pubmed 21190574