Clinical outcomes of cryoballoon ablation for pulmonary vein isolation
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Clinical outcomes of cryoballoon ablation for pulmonary vein isolation : Impact of intraprocedural heart rhythm. / Reissmann, Bruno; Heeger, Christian-H; Opitz, Karena; Schlüter, Michael; Wohlmuth, Peter; Rottner, Laura; Fink, Thomas; Gerds-Li, Jin-Hong; Mathew, Shibu; Lemes, Christine; Maurer, Tilman; Ouyang, Feifan; Kuck, Karl-Heinz; Rillig, Andreas; Schöppenthau, Doreen; Metzner, Andreas.
in: CARDIOL J, Jahrgang 29, Nr. 5, 2022, S. 807-814.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Clinical outcomes of cryoballoon ablation for pulmonary vein isolation
T2 - Impact of intraprocedural heart rhythm
AU - Reissmann, Bruno
AU - Heeger, Christian-H
AU - Opitz, Karena
AU - Schlüter, Michael
AU - Wohlmuth, Peter
AU - Rottner, Laura
AU - Fink, Thomas
AU - Gerds-Li, Jin-Hong
AU - Mathew, Shibu
AU - Lemes, Christine
AU - Maurer, Tilman
AU - Ouyang, Feifan
AU - Kuck, Karl-Heinz
AU - Rillig, Andreas
AU - Schöppenthau, Doreen
AU - Metzner, Andreas
PY - 2022
Y1 - 2022
N2 - BACKGROUND: The current study sought to assess the impact of the intraprocedural heart rhythm (sinus rhythm [SR] vs. atrial fibrillation [AF]) on acute procedural characteristics, durability of pulmonary vein isolation (PVI) and long-term clinical outcomes of cryoballoon (CB) ablation.METHODS: A total of 195 patients with symptomatic paroxysmal (n = 136) or persistent AF (n = 59) underwent CB-based PVI. Ablation procedures were either performed in SR (SR group; n = 147) or during AF (AF group; n = 48). Persistent AF was more frequent in the AF group than in the SR group (62% vs. 20%). All other patient baseline characteristics did not differ between the two groups.RESULTS: The nadir temperature during the CB applications was significantly lower in the AF group than in patients in the SR group (-49 [interquartile range, -44; -54]°C vs. -47 [-42; -52]°C, p = 0.002). Median procedure and fluoroscopy times as well as the rate of real-time recordings were not different between the two groups. Repeat ablation for the treatment of atrial arrhythmia recurrence was performed in 60 patients (SR: 44 [30%] patients; AF: 16 [33%] patients), with a trend towards a lower rate of pulmonary vein reconnections in the AF group (p = 0.07). There was no difference in 3-year arrhythmia-free survival (p = 0.8).CONCLUSIONS: Cryoballoon-based PVI during AF results in lower nadir balloon temperatures and a trend towards a higher durability of PVI as compared to procedures performed in SR. The rate of real-time PVI recordings was not affected by the intraprocedural heart rhythm.
AB - BACKGROUND: The current study sought to assess the impact of the intraprocedural heart rhythm (sinus rhythm [SR] vs. atrial fibrillation [AF]) on acute procedural characteristics, durability of pulmonary vein isolation (PVI) and long-term clinical outcomes of cryoballoon (CB) ablation.METHODS: A total of 195 patients with symptomatic paroxysmal (n = 136) or persistent AF (n = 59) underwent CB-based PVI. Ablation procedures were either performed in SR (SR group; n = 147) or during AF (AF group; n = 48). Persistent AF was more frequent in the AF group than in the SR group (62% vs. 20%). All other patient baseline characteristics did not differ between the two groups.RESULTS: The nadir temperature during the CB applications was significantly lower in the AF group than in patients in the SR group (-49 [interquartile range, -44; -54]°C vs. -47 [-42; -52]°C, p = 0.002). Median procedure and fluoroscopy times as well as the rate of real-time recordings were not different between the two groups. Repeat ablation for the treatment of atrial arrhythmia recurrence was performed in 60 patients (SR: 44 [30%] patients; AF: 16 [33%] patients), with a trend towards a lower rate of pulmonary vein reconnections in the AF group (p = 0.07). There was no difference in 3-year arrhythmia-free survival (p = 0.8).CONCLUSIONS: Cryoballoon-based PVI during AF results in lower nadir balloon temperatures and a trend towards a higher durability of PVI as compared to procedures performed in SR. The rate of real-time PVI recordings was not affected by the intraprocedural heart rhythm.
U2 - 10.5603/CJ.a2020.0147
DO - 10.5603/CJ.a2020.0147
M3 - SCORING: Journal article
C2 - 33140384
VL - 29
SP - 807
EP - 814
JO - CARDIOL J
JF - CARDIOL J
SN - 1897-5593
IS - 5
ER -