Clinical outcome of children with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia treated between 1995 and 2005.
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Clinical outcome of children with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia treated between 1995 and 2005. / Aricò, Maurizio; Schrappe, Martin; Hunger, Stephen P; Carroll, William L; Conter, Valentino; Galimberti, Stefania; Manabe, Atsushi; Saha, Vaskar; Baruchel, André; Vettenranta, Kim; Horibe, Keizo; Benoit, Yves; Pieters, Rob; Escherich, Gabriele; Silverman, Lewis B; Pui, Ching-Hon; Valsecchi, Maria Grazia.
in: J CLIN ONCOL, Jahrgang 28, Nr. 31, 31, 2010, S. 4755-4761.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Clinical outcome of children with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia treated between 1995 and 2005.
AU - Aricò, Maurizio
AU - Schrappe, Martin
AU - Hunger, Stephen P
AU - Carroll, William L
AU - Conter, Valentino
AU - Galimberti, Stefania
AU - Manabe, Atsushi
AU - Saha, Vaskar
AU - Baruchel, André
AU - Vettenranta, Kim
AU - Horibe, Keizo
AU - Benoit, Yves
AU - Pieters, Rob
AU - Escherich, Gabriele
AU - Silverman, Lewis B
AU - Pui, Ching-Hon
AU - Valsecchi, Maria Grazia
PY - 2010
Y1 - 2010
N2 - In a previous analysis of 326 children with Philadelphia chromosome (Ph) -positive acute lymphoblastic leukemia (ALL) treated between 1986 and 1996, hematopoietic stem-cell transplantation from HLA-matched related donors, but not from unrelated donors, offered a superior outcome than chemotherapy alone. To evaluate the impact of recent improvements in chemotherapy and transplantation, we performed a similar analysis on patients treated in the following decade.
AB - In a previous analysis of 326 children with Philadelphia chromosome (Ph) -positive acute lymphoblastic leukemia (ALL) treated between 1986 and 1996, hematopoietic stem-cell transplantation from HLA-matched related donors, but not from unrelated donors, offered a superior outcome than chemotherapy alone. To evaluate the impact of recent improvements in chemotherapy and transplantation, we performed a similar analysis on patients treated in the following decade.
KW - Humans
KW - Male
KW - Female
KW - Adolescent
KW - Multivariate Analysis
KW - Treatment Outcome
KW - dosage
KW - Child
KW - Follow-Up Studies
KW - Disease-Free Survival
KW - Proportional Hazards Models
KW - Child, Preschool
KW - Odds Ratio
KW - Retrospective Studies
KW - Remission Induction
KW - Antineoplastic Agents administration
KW - HLA Antigens immunology
KW - Hematopoietic Stem Cell Transplantation
KW - Kaplan-Meier Estimate
KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma diagnosis
KW - Protein Kinase Inhibitors administration
KW - Humans
KW - Male
KW - Female
KW - Adolescent
KW - Multivariate Analysis
KW - Treatment Outcome
KW - dosage
KW - Child
KW - Follow-Up Studies
KW - Disease-Free Survival
KW - Proportional Hazards Models
KW - Child, Preschool
KW - Odds Ratio
KW - Retrospective Studies
KW - Remission Induction
KW - Antineoplastic Agents administration
KW - HLA Antigens immunology
KW - Hematopoietic Stem Cell Transplantation
KW - Kaplan-Meier Estimate
KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma diagnosis
KW - Protein Kinase Inhibitors administration
M3 - SCORING: Zeitschriftenaufsatz
VL - 28
SP - 4755
EP - 4761
JO - J CLIN ONCOL
JF - J CLIN ONCOL
SN - 0732-183X
IS - 31
M1 - 31
ER -