Clinical impact of FLT3 mutation load in acute promyelocytic leukemia with t(15;17)/PML-RARA.
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Clinical impact of FLT3 mutation load in acute promyelocytic leukemia with t(15;17)/PML-RARA. / Schnittger, Susanne; Bacher, Ulrike; Haferlach, Claudia; Kern, Wolfgang; Alpermann, Tamara; Haferlach, Torsten.
in: HAEMATOLOGICA, Jahrgang 96, Nr. 12, 12, 2011, S. 1799-1807.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Clinical impact of FLT3 mutation load in acute promyelocytic leukemia with t(15;17)/PML-RARA.
AU - Schnittger, Susanne
AU - Bacher, Ulrike
AU - Haferlach, Claudia
AU - Kern, Wolfgang
AU - Alpermann, Tamara
AU - Haferlach, Torsten
PY - 2011
Y1 - 2011
N2 - Combined treatment with all-trans-retinoic acid and chemotherapy is extremely efficient in patients with acute promyelocytic leukemia with t(15;17)/PML-RARA, but up to 15% of patients relapse.
AB - Combined treatment with all-trans-retinoic acid and chemotherapy is extremely efficient in patients with acute promyelocytic leukemia with t(15;17)/PML-RARA, but up to 15% of patients relapse.
KW - Adult
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Survival Rate
KW - Disease-Free Survival
KW - Antineoplastic Agents/administration & dosage
KW - Chromosomes, Human, Pair 15/genetics
KW - Chromosomes, Human, Pair 17/genetics
KW - Leukemia, Promyelocytic, Acute/drug therapy/genetics/mortality
KW - Oncogene Proteins, Fusion/genetics
KW - Translocation, Genetic
KW - Tretinoin/administration & dosage
KW - fms-Like Tyrosine Kinase 3/genetics
KW - Adult
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Survival Rate
KW - Disease-Free Survival
KW - Antineoplastic Agents/administration & dosage
KW - Chromosomes, Human, Pair 15/genetics
KW - Chromosomes, Human, Pair 17/genetics
KW - Leukemia, Promyelocytic, Acute/drug therapy/genetics/mortality
KW - Oncogene Proteins, Fusion/genetics
KW - Translocation, Genetic
KW - Tretinoin/administration & dosage
KW - fms-Like Tyrosine Kinase 3/genetics
U2 - 10.3324/haematol.2011.049007
DO - 10.3324/haematol.2011.049007
M3 - SCORING: Journal article
VL - 96
SP - 1799
EP - 1807
JO - HAEMATOLOGICA
JF - HAEMATOLOGICA
SN - 0390-6078
IS - 12
M1 - 12
ER -