Circulating levels of cell adhesion molecule L1 as a prognostic marker in gastrointestinal stromal tumor patients.
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Circulating levels of cell adhesion molecule L1 as a prognostic marker in gastrointestinal stromal tumor patients. / Zander, Hilke; Rawnaq, Tamina; von Wedemeyer, Max; Tachezy, Michael; Kunkel, Miriam; Wolters, Gerrit; Bockhorn, Maximilian; Schachner, Melitta; Izbicki, Jakob R.; Kaifi, Jussuf.
in: BMC CANCER, Jahrgang 11, 2011, S. 1-7.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Circulating levels of cell adhesion molecule L1 as a prognostic marker in gastrointestinal stromal tumor patients.
AU - Zander, Hilke
AU - Rawnaq, Tamina
AU - von Wedemeyer, Max
AU - Tachezy, Michael
AU - Kunkel, Miriam
AU - Wolters, Gerrit
AU - Bockhorn, Maximilian
AU - Schachner, Melitta
AU - Izbicki, Jakob R.
AU - Kaifi, Jussuf
PY - 2011
Y1 - 2011
N2 - L1 cell adhesion molecule (CD171) is expressed in many malignant tumors and its expression correlates with unfavourable outcome. It thus represents a target for tumor diagnosis and therapy. An earlier study conducted by our group identified L1 expression levels in primary gastrointestinal stromal tumors (GIST) as a prognostic marker. The aim of the current study was to compare L1 serum levels of GIST patients with those of healthy controls and to determine whether levels of soluble L1 in sera could serve as a prognostic marker.
AB - L1 cell adhesion molecule (CD171) is expressed in many malignant tumors and its expression correlates with unfavourable outcome. It thus represents a target for tumor diagnosis and therapy. An earlier study conducted by our group identified L1 expression levels in primary gastrointestinal stromal tumors (GIST) as a prognostic marker. The aim of the current study was to compare L1 serum levels of GIST patients with those of healthy controls and to determine whether levels of soluble L1 in sera could serve as a prognostic marker.
KW - Adult
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Aged, 80 and over
KW - Prognosis
KW - Survival Analysis
KW - Retrospective Studies
KW - Recurrence
KW - Case-Control Studies
KW - Tumor Markers, Biological/blood
KW - Gastrointestinal Stromal Tumors/blood/diagnosis/mortality
KW - Neural Cell Adhesion Molecule L1/blood
KW - Adult
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Aged, 80 and over
KW - Prognosis
KW - Survival Analysis
KW - Retrospective Studies
KW - Recurrence
KW - Case-Control Studies
KW - Tumor Markers, Biological/blood
KW - Gastrointestinal Stromal Tumors/blood/diagnosis/mortality
KW - Neural Cell Adhesion Molecule L1/blood
U2 - 10.1186/1471-2407-11-189
DO - 10.1186/1471-2407-11-189
M3 - SCORING: Journal article
VL - 11
SP - 1
EP - 7
JO - BMC CANCER
JF - BMC CANCER
SN - 1471-2407
ER -