Chronic liver inflammation dominated by interferon-γ can prevent hepatocarcinogenesis.
Beteiligte Einrichtungen
Abstract
Inflammation is a major stimulus for carcinogenesis; however inflammation can also inhibit tumor growth and deplete malignant cells. The differences between cancer-promoting and cancer-inhibitory inflammation are not clear. We identified Interferon-? as a major mediator of cancer-inhibitory inflammation that promotes anti-cancer immunity in the liver and sensitizes malignant hepatocytes for apoptosis.
Bibliografische Daten
| Originalsprache | Englisch |
|---|---|
| Aufsatznummer | 2 |
| Status | Veröffentlicht - 2012 |
| pubmed | 22720249 |
|---|
