Chest radiography for the diagnosis of acute aortic syndrome
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Chest radiography for the diagnosis of acute aortic syndrome. / von Kodolitsch, Yskert; Nienaber, Christoph A; Dieckmann, Christoph; Schwartz, Ann G; Hofmann, Thomas; Brekenfeld, Caspar; Nicolas, Volkmar; Berger, Jürgen; Meinertz, Thomas.
in: AM J MED, Jahrgang 116, Nr. 2, 15.01.2004, S. 73-77.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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T1 - Chest radiography for the diagnosis of acute aortic syndrome
AU - von Kodolitsch, Yskert
AU - Nienaber, Christoph A
AU - Dieckmann, Christoph
AU - Schwartz, Ann G
AU - Hofmann, Thomas
AU - Brekenfeld, Caspar
AU - Nicolas, Volkmar
AU - Berger, Jürgen
AU - Meinertz, Thomas
PY - 2004/1/15
Y1 - 2004/1/15
N2 - PURPOSE: We sought to assess the diagnostic accuracy of routine chest radiography for the acute aortic syndrome (dissection, intramural hematoma, penetrating ulcer, or nondissecting aneurysm).METHODS: During a 6-year period, 216 patients (143 men, 73 women; mean [+/- SD] age, 58 +/- 17 years) underwent chest radiography for suspected acute aortic syndrome. Chest films were re-evaluated blindly for aortic disease, based on an overall impression using standard criteria such as widening of the aortic contour and mediastinal shadow. Findings were matched to tomographic images, anatomical inspection, or both, as the criterion standard; aortic disease was confirmed in 109 (50%) of the patients.RESULTS: Chest radiography had a sensitivity of 64% (70/109) and a specificity of 86% (92/107) for aortic disease. Sensitivity was 67% (38/57) for overt aortic dissection, 61% (22/36) for nondissecting aneurysm, and 63% (10/16) for intramural hemorrhage or penetrating ulcer. However, sensitivity was lower for pathology confined to the proximal aorta (47% [21/45]) than for disease involving distal aortic segments (77% [49/64]). A receiver operating characteristic curve analysis of aortic diameters failed to identify a threshold for the diagnosis of aortic disease.CONCLUSION: Chest radiography is of limited value for diagnosing the acute aortic syndrome, particularly for conditions confined to the ascending aorta. Since a definitive diagnosis is required in any patient with clinically suspected acute aortic syndrome, routine chest radiography should be replaced by tomographic aortic imaging.
AB - PURPOSE: We sought to assess the diagnostic accuracy of routine chest radiography for the acute aortic syndrome (dissection, intramural hematoma, penetrating ulcer, or nondissecting aneurysm).METHODS: During a 6-year period, 216 patients (143 men, 73 women; mean [+/- SD] age, 58 +/- 17 years) underwent chest radiography for suspected acute aortic syndrome. Chest films were re-evaluated blindly for aortic disease, based on an overall impression using standard criteria such as widening of the aortic contour and mediastinal shadow. Findings were matched to tomographic images, anatomical inspection, or both, as the criterion standard; aortic disease was confirmed in 109 (50%) of the patients.RESULTS: Chest radiography had a sensitivity of 64% (70/109) and a specificity of 86% (92/107) for aortic disease. Sensitivity was 67% (38/57) for overt aortic dissection, 61% (22/36) for nondissecting aneurysm, and 63% (10/16) for intramural hemorrhage or penetrating ulcer. However, sensitivity was lower for pathology confined to the proximal aorta (47% [21/45]) than for disease involving distal aortic segments (77% [49/64]). A receiver operating characteristic curve analysis of aortic diameters failed to identify a threshold for the diagnosis of aortic disease.CONCLUSION: Chest radiography is of limited value for diagnosing the acute aortic syndrome, particularly for conditions confined to the ascending aorta. Since a definitive diagnosis is required in any patient with clinically suspected acute aortic syndrome, routine chest radiography should be replaced by tomographic aortic imaging.
KW - Acute Disease
KW - Adult
KW - Aged
KW - Aneurysm, Dissecting/diagnostic imaging
KW - Aortic Aneurysm/diagnostic imaging
KW - Aortic Diseases/diagnostic imaging
KW - Female
KW - Hematoma/diagnostic imaging
KW - Humans
KW - Likelihood Functions
KW - Male
KW - Middle Aged
KW - ROC Curve
KW - Radiography
KW - Sensitivity and Specificity
U2 - 10.1016/j.amjmed.2003.08.030
DO - 10.1016/j.amjmed.2003.08.030
M3 - SCORING: Journal article
C2 - 14715319
VL - 116
SP - 73
EP - 77
JO - AM J MED
JF - AM J MED
SN - 0002-9343
IS - 2
ER -