Characteristics and outcomes of patients with pT4 urothelial carcinoma at radical cystectomy: a retrospective international study of 583 patients.

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Characteristics and outcomes of patients with pT4 urothelial carcinoma at radical cystectomy: a retrospective international study of 583 patients. / Tilki, Derya; Svatek, Robert S; Karakiewicz, Pierre I; Isbarn, Hendrik; Reich, Oliver; Kassouf, Wassim; Fradet, Yves; Novara, Giacomo; Fritsche, Hans-Martin; Bastian, Patrick J; Izawa, Jonathan I; Stief, Christian G; Ficarra, Vincenzo; Lerner, Seth P; Schoenberg, Mark; Dinney, Colin P; Skinner, Eila; Lotan, Yair; Sagalowsky, Arthur I; Shariat, Shahrokh F.

in: J UROLOGY, Jahrgang 183, Nr. 1, 1, 2010, S. 87-93.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

Harvard

Tilki, D, Svatek, RS, Karakiewicz, PI, Isbarn, H, Reich, O, Kassouf, W, Fradet, Y, Novara, G, Fritsche, H-M, Bastian, PJ, Izawa, JI, Stief, CG, Ficarra, V, Lerner, SP, Schoenberg, M, Dinney, CP, Skinner, E, Lotan, Y, Sagalowsky, AI & Shariat, SF 2010, 'Characteristics and outcomes of patients with pT4 urothelial carcinoma at radical cystectomy: a retrospective international study of 583 patients.', J UROLOGY, Jg. 183, Nr. 1, 1, S. 87-93. <http://www.ncbi.nlm.nih.gov/pubmed/19942232?dopt=Citation>

APA

Tilki, D., Svatek, R. S., Karakiewicz, P. I., Isbarn, H., Reich, O., Kassouf, W., Fradet, Y., Novara, G., Fritsche, H-M., Bastian, P. J., Izawa, J. I., Stief, C. G., Ficarra, V., Lerner, S. P., Schoenberg, M., Dinney, C. P., Skinner, E., Lotan, Y., Sagalowsky, A. I., & Shariat, S. F. (2010). Characteristics and outcomes of patients with pT4 urothelial carcinoma at radical cystectomy: a retrospective international study of 583 patients. J UROLOGY, 183(1), 87-93. [1]. http://www.ncbi.nlm.nih.gov/pubmed/19942232?dopt=Citation

Vancouver

Bibtex

@article{0e8d68d8a5fc4186b0a3b3badabfbfe3,
title = "Characteristics and outcomes of patients with pT4 urothelial carcinoma at radical cystectomy: a retrospective international study of 583 patients.",
abstract = "PURPOSE: We describe cancer specific outcomes in patients with pT4 bladder urothelial carcinoma at radical cystectomy in a large international cohort. MATERIALS AND METHODS: We reviewed the records of 4,257 patients treated with radical cystectomy for bladder urothelial carcinoma at 12 centers. No patient received any preoperative systemic chemotherapy or radiotherapy. RESULTS: Of the 4,257 patients 583 (14%) had pT4 bladder urothelial carcinoma, of whom 83.7% were male, 85.2% had substage pT4a disease, 24.9% had positive soft tissue surgical margins, 57.8% had lymphovascular invasion and 53.5% had lymph node metastasis. Median followup was 55.0 months. Overall estimated 5-year recurrence-free and cancer specific survival was 29% (95% CI 22-32) and 31% (95% CI 25-36), respectively. On multivariate analysis female gender (p = 0.005 and p = 0.001), positive soft tissue surgical margins (p = 0.014 and p",
author = "Derya Tilki and Svatek, {Robert S} and Karakiewicz, {Pierre I} and Hendrik Isbarn and Oliver Reich and Wassim Kassouf and Yves Fradet and Giacomo Novara and Hans-Martin Fritsche and Bastian, {Patrick J} and Izawa, {Jonathan I} and Stief, {Christian G} and Vincenzo Ficarra and Lerner, {Seth P} and Mark Schoenberg and Dinney, {Colin P} and Eila Skinner and Yair Lotan and Sagalowsky, {Arthur I} and Shariat, {Shahrokh F}",
year = "2010",
language = "Deutsch",
volume = "183",
pages = "87--93",
journal = "J UROLOGY",
issn = "0022-5347",
publisher = "Elsevier Inc.",
number = "1",

}

RIS

TY - JOUR

T1 - Characteristics and outcomes of patients with pT4 urothelial carcinoma at radical cystectomy: a retrospective international study of 583 patients.

AU - Tilki, Derya

AU - Svatek, Robert S

AU - Karakiewicz, Pierre I

AU - Isbarn, Hendrik

AU - Reich, Oliver

AU - Kassouf, Wassim

AU - Fradet, Yves

AU - Novara, Giacomo

AU - Fritsche, Hans-Martin

AU - Bastian, Patrick J

AU - Izawa, Jonathan I

AU - Stief, Christian G

AU - Ficarra, Vincenzo

AU - Lerner, Seth P

AU - Schoenberg, Mark

AU - Dinney, Colin P

AU - Skinner, Eila

AU - Lotan, Yair

AU - Sagalowsky, Arthur I

AU - Shariat, Shahrokh F

PY - 2010

Y1 - 2010

N2 - PURPOSE: We describe cancer specific outcomes in patients with pT4 bladder urothelial carcinoma at radical cystectomy in a large international cohort. MATERIALS AND METHODS: We reviewed the records of 4,257 patients treated with radical cystectomy for bladder urothelial carcinoma at 12 centers. No patient received any preoperative systemic chemotherapy or radiotherapy. RESULTS: Of the 4,257 patients 583 (14%) had pT4 bladder urothelial carcinoma, of whom 83.7% were male, 85.2% had substage pT4a disease, 24.9% had positive soft tissue surgical margins, 57.8% had lymphovascular invasion and 53.5% had lymph node metastasis. Median followup was 55.0 months. Overall estimated 5-year recurrence-free and cancer specific survival was 29% (95% CI 22-32) and 31% (95% CI 25-36), respectively. On multivariate analysis female gender (p = 0.005 and p = 0.001), positive soft tissue surgical margins (p = 0.014 and p

AB - PURPOSE: We describe cancer specific outcomes in patients with pT4 bladder urothelial carcinoma at radical cystectomy in a large international cohort. MATERIALS AND METHODS: We reviewed the records of 4,257 patients treated with radical cystectomy for bladder urothelial carcinoma at 12 centers. No patient received any preoperative systemic chemotherapy or radiotherapy. RESULTS: Of the 4,257 patients 583 (14%) had pT4 bladder urothelial carcinoma, of whom 83.7% were male, 85.2% had substage pT4a disease, 24.9% had positive soft tissue surgical margins, 57.8% had lymphovascular invasion and 53.5% had lymph node metastasis. Median followup was 55.0 months. Overall estimated 5-year recurrence-free and cancer specific survival was 29% (95% CI 22-32) and 31% (95% CI 25-36), respectively. On multivariate analysis female gender (p = 0.005 and p = 0.001), positive soft tissue surgical margins (p = 0.014 and p

M3 - SCORING: Zeitschriftenaufsatz

VL - 183

SP - 87

EP - 93

JO - J UROLOGY

JF - J UROLOGY

SN - 0022-5347

IS - 1

M1 - 1

ER -