cGMP Signaling in the Cardiovascular System-The Role of Compartmentation and Its Live Cell Imaging
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cGMP Signaling in the Cardiovascular System-The Role of Compartmentation and Its Live Cell Imaging. / Bork, Nadja I; Nikolaev, Viacheslav O.
in: INT J MOL SCI, Jahrgang 19, Nr. 3, 10.03.2018, S. 801.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung
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TY - JOUR
T1 - cGMP Signaling in the Cardiovascular System-The Role of Compartmentation and Its Live Cell Imaging
AU - Bork, Nadja I
AU - Nikolaev, Viacheslav O
PY - 2018/3/10
Y1 - 2018/3/10
N2 - The ubiquitous second messenger 3',5'-cyclic guanosine monophosphate (cGMP) regulates multiple physiologic processes in the cardiovascular system. Its intracellular effects are mediated by stringently controlled subcellular microdomains. In this review, we will illustrate the current techniques available for real-time cGMP measurements with a specific focus on live cell imaging methods. We will also discuss currently accepted and emerging mechanisms of cGMP compartmentation in the cardiovascular system.
AB - The ubiquitous second messenger 3',5'-cyclic guanosine monophosphate (cGMP) regulates multiple physiologic processes in the cardiovascular system. Its intracellular effects are mediated by stringently controlled subcellular microdomains. In this review, we will illustrate the current techniques available for real-time cGMP measurements with a specific focus on live cell imaging methods. We will also discuss currently accepted and emerging mechanisms of cGMP compartmentation in the cardiovascular system.
KW - Journal Article
KW - Review
U2 - 10.3390/ijms19030801
DO - 10.3390/ijms19030801
M3 - SCORING: Review article
C2 - 29534460
VL - 19
SP - 801
JO - INT J MOL SCI
JF - INT J MOL SCI
SN - 1661-6596
IS - 3
ER -