CD8-mediated inflammatory central nervous system disorders.

Abstract

In central nervous system (CNS) autoimmune disorders, CD8+ T cells have been reported to exert cytotoxic as well as regulatory functions. In virus-induced (meningo) encephalitis, they are essential for viral clearance, but can also cause severe immunopathology. This review aims to summarize the multifaceted roles CD8+ T cells can play in inflammatory CNS disorders.

Bibliografische Daten

OriginalspracheEnglisch
Aufsatznummer3
ISSN1350-7540
StatusVeröffentlicht - 2012
pubmed 22547102