PortalPublikationenBone ablation without thermal or acoustic mechanical injury ...

Bone ablation without thermal or acoustic mechanical injury via a novel picosecond infrared laser (PIRL)

Standard

Bone ablation without thermal or acoustic mechanical injury via a novel picosecond infrared laser (PIRL). / Jowett, Nathan; Wöllmer, Wolfgang; Reimer, Rudolph; Zustin, Josef; Schumacher, Udo; Wiseman, Paul W; Mlynarek, Alex M; Böttcher, Arne; Dalchow, Carsten V; Lörincz, Balazs B; Knecht, Rainald; Miller, R J Dwayne.

in: OTOLARYNG HEAD NECK, Jahrgang 150, Nr. 3, 01.03.2014, S. 385-93.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Jowett, N, Wöllmer, W, Reimer, R, Zustin, J, Schumacher, U, Wiseman, PW, Mlynarek, AM, Böttcher, A, Dalchow, CV, Lörincz, BB, Knecht, R & Miller, RJD 2014, 'Bone ablation without thermal or acoustic mechanical injury via a novel picosecond infrared laser (PIRL)', OTOLARYNG HEAD NECK, Jg. 150, Nr. 3, S. 385-93. https://doi.org/10.1177/0194599813517213

APA

Jowett, N., Wöllmer, W., Reimer, R., Zustin, J., Schumacher, U., Wiseman, P. W., Mlynarek, A. M., Böttcher, A., Dalchow, C. V., Lörincz, B. B., Knecht, R., & Miller, R. J. D. (2014). Bone ablation without thermal or acoustic mechanical injury via a novel picosecond infrared laser (PIRL). OTOLARYNG HEAD NECK, 150(3), 385-93. https://doi.org/10.1177/0194599813517213

Vancouver

Jowett N, Wöllmer W, Reimer R, Zustin J, Schumacher U, Wiseman PW et al. Bone ablation without thermal or acoustic mechanical injury via a novel picosecond infrared laser (PIRL). OTOLARYNG HEAD NECK. 2014 Mär 1;150(3):385-93. https://doi.org/10.1177/0194599813517213

Bibtex

@article{3462d5bae3724a5e87f8b63322d88200,
title = "Bone ablation without thermal or acoustic mechanical injury via a novel picosecond infrared laser (PIRL)",
abstract = "BACKGROUND AND OBJECTIVE: A precise means to cut bone without significant thermal or mechanical injury has thus far remained elusive. A novel non-ionizing ultrafast pulsed picosecond infrared laser (PIRL) may provide the solution. Tissue ablation with the PIRL occurs via a photothermal process with thermal and stress confinement, resulting in efficient material ejection greatly enhanced through front surface spallation photomechanical effects. By comparison, the Er:YAG laser (EYL) ablates via photothermal and cavitation-induced photomechanical effects without thermal or acoustic confinement, leading to significant collateral tissue injury. This study compared PIRL and EYL bone ablation by infrared thermography (IRT), environmental scanning electron microscopy (ESEM), and histology.STUDY DESIGN: Prospective, comparative, ex vivo animal model.SETTING: Optics laboratory.SUBJECTS AND METHODS: Ten circular area defects were ablated in ex vivo chicken humeral cortex using PIRL and EYL at similar average power (~70 mW) under IRT. Following fixation, ESEM and undecalcified light microscopy images were obtained and examined for signs of cellular injury.RESULTS: Peak rise in surface temperature was negligible and lower for PIRL (1.56 °C; 95% CI, 0.762-2.366) compared to EYL ablation (12.99 °C; 95% CI, 12.189-13.792) (P < .001). ESEM and light microscopy demonstrated preserved cortical microstructure following PIRL ablation in contrast to diffuse thermal injury seen with EYL ablation. Microfractures were not observed.CONCLUSION: Ablation of cortical bone using the PIRL generates negligible and significantly less heat than EYL ablation while preserving cortical microstructure. This novel laser has great potential in advancing surgical techniques where precision osseous manipulation is required.",
keywords = "Animals, Body Temperature, Burns, Chickens, Disease Models, Animal, Female, Follow-Up Studies, Humerus, Laser Therapy, Microscopy, Electron, Scanning, Prospective Studies, Thermography",
author = "Nathan Jowett and Wolfgang W{\"o}llmer and Rudolph Reimer and Josef Zustin and Udo Schumacher and Wiseman, {Paul W} and Mlynarek, {Alex M} and Arne B{\"o}ttcher and Dalchow, {Carsten V} and L{\"o}rincz, {Balazs B} and Rainald Knecht and Miller, {R J Dwayne}",
year = "2014",
month = mar,
day = "1",
doi = "10.1177/0194599813517213",
language = "English",
volume = "150",
pages = "385--93",
journal = "OTOLARYNG HEAD NECK",
issn = "0194-5998",
publisher = "Mosby Inc.",
number = "3",

}

RIS

TY - JOUR

T1 - Bone ablation without thermal or acoustic mechanical injury via a novel picosecond infrared laser (PIRL)

AU - Jowett, Nathan

AU - Wöllmer, Wolfgang

AU - Reimer, Rudolph

AU - Zustin, Josef

AU - Schumacher, Udo

AU - Wiseman, Paul W

AU - Mlynarek, Alex M

AU - Böttcher, Arne

AU - Dalchow, Carsten V

AU - Lörincz, Balazs B

AU - Knecht, Rainald

AU - Miller, R J Dwayne

PY - 2014/3/1

Y1 - 2014/3/1

N2 - BACKGROUND AND OBJECTIVE: A precise means to cut bone without significant thermal or mechanical injury has thus far remained elusive. A novel non-ionizing ultrafast pulsed picosecond infrared laser (PIRL) may provide the solution. Tissue ablation with the PIRL occurs via a photothermal process with thermal and stress confinement, resulting in efficient material ejection greatly enhanced through front surface spallation photomechanical effects. By comparison, the Er:YAG laser (EYL) ablates via photothermal and cavitation-induced photomechanical effects without thermal or acoustic confinement, leading to significant collateral tissue injury. This study compared PIRL and EYL bone ablation by infrared thermography (IRT), environmental scanning electron microscopy (ESEM), and histology.STUDY DESIGN: Prospective, comparative, ex vivo animal model.SETTING: Optics laboratory.SUBJECTS AND METHODS: Ten circular area defects were ablated in ex vivo chicken humeral cortex using PIRL and EYL at similar average power (~70 mW) under IRT. Following fixation, ESEM and undecalcified light microscopy images were obtained and examined for signs of cellular injury.RESULTS: Peak rise in surface temperature was negligible and lower for PIRL (1.56 °C; 95% CI, 0.762-2.366) compared to EYL ablation (12.99 °C; 95% CI, 12.189-13.792) (P < .001). ESEM and light microscopy demonstrated preserved cortical microstructure following PIRL ablation in contrast to diffuse thermal injury seen with EYL ablation. Microfractures were not observed.CONCLUSION: Ablation of cortical bone using the PIRL generates negligible and significantly less heat than EYL ablation while preserving cortical microstructure. This novel laser has great potential in advancing surgical techniques where precision osseous manipulation is required.

AB - BACKGROUND AND OBJECTIVE: A precise means to cut bone without significant thermal or mechanical injury has thus far remained elusive. A novel non-ionizing ultrafast pulsed picosecond infrared laser (PIRL) may provide the solution. Tissue ablation with the PIRL occurs via a photothermal process with thermal and stress confinement, resulting in efficient material ejection greatly enhanced through front surface spallation photomechanical effects. By comparison, the Er:YAG laser (EYL) ablates via photothermal and cavitation-induced photomechanical effects without thermal or acoustic confinement, leading to significant collateral tissue injury. This study compared PIRL and EYL bone ablation by infrared thermography (IRT), environmental scanning electron microscopy (ESEM), and histology.STUDY DESIGN: Prospective, comparative, ex vivo animal model.SETTING: Optics laboratory.SUBJECTS AND METHODS: Ten circular area defects were ablated in ex vivo chicken humeral cortex using PIRL and EYL at similar average power (~70 mW) under IRT. Following fixation, ESEM and undecalcified light microscopy images were obtained and examined for signs of cellular injury.RESULTS: Peak rise in surface temperature was negligible and lower for PIRL (1.56 °C; 95% CI, 0.762-2.366) compared to EYL ablation (12.99 °C; 95% CI, 12.189-13.792) (P < .001). ESEM and light microscopy demonstrated preserved cortical microstructure following PIRL ablation in contrast to diffuse thermal injury seen with EYL ablation. Microfractures were not observed.CONCLUSION: Ablation of cortical bone using the PIRL generates negligible and significantly less heat than EYL ablation while preserving cortical microstructure. This novel laser has great potential in advancing surgical techniques where precision osseous manipulation is required.

KW - Animals

KW - Body Temperature

KW - Burns

KW - Chickens

KW - Disease Models, Animal

KW - Female

KW - Follow-Up Studies

KW - Humerus

KW - Laser Therapy

KW - Microscopy, Electron, Scanning

KW - Prospective Studies

KW - Thermography

U2 - 10.1177/0194599813517213

DO - 10.1177/0194599813517213

M3 - SCORING: Journal article

C2 - 24376121

VL - 150

SP - 385

EP - 393

JO - OTOLARYNG HEAD NECK

JF - OTOLARYNG HEAD NECK

SN - 0194-5998

IS - 3

ER -