Body mass index does not predict prostate-specific antigen or percent free prostate-specific antigen in men undergoing prostate cancer screening.
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Body mass index does not predict prostate-specific antigen or percent free prostate-specific antigen in men undergoing prostate cancer screening. / Hutterer, Georg; Perrotte, Paul; Gallina, Andrea; Walz, Jochen; Jeldres, Claudio; Traumann, Miriam; Suardi, Nazareno; Saad, Fred; Bénard, François; Valiquette, Luc; McCormack, Michael; Graefen, Markus; Montorsi, Francesco; Karakiewicz, Pierre I.
in: EUR J CANCER, Jahrgang 43, Nr. 7, 7, 2007, S. 1180-1187.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Body mass index does not predict prostate-specific antigen or percent free prostate-specific antigen in men undergoing prostate cancer screening.
AU - Hutterer, Georg
AU - Perrotte, Paul
AU - Gallina, Andrea
AU - Walz, Jochen
AU - Jeldres, Claudio
AU - Traumann, Miriam
AU - Suardi, Nazareno
AU - Saad, Fred
AU - Bénard, François
AU - Valiquette, Luc
AU - McCormack, Michael
AU - Graefen, Markus
AU - Montorsi, Francesco
AU - Karakiewicz, Pierre I
PY - 2007
Y1 - 2007
N2 - OBJECTIVES: Body mass index (BMI) may alter serum prostate specific antigen (PSA) and percent free PSA (%fPSA) and may mask the risk of prostate cancer. We investigated the relationship between BMI and PSA or %fPSA. MATERIALS AND METHODS: Height, weight, PSA and %fPSA were assessed in 616 consecutive screened men without prostate cancer. Continuously coded and categorised BMI was studied. Statistical analyses consisted of ANOVA, linear regression, bivariate and partial correlations. RESULTS: Median age was 57 years. Median PSA was 1.0 and median %fPSA was 26. Median BMI was 25.8 kg/m(2). Neither continuously coded nor categorised BMI correlated with either PSA or %fPSA in unadjusted or age-adjusted analyses (all p values > or = 0.3). CONCLUSIONS: Body mass index does not affect PSA or %fPSA in men without known prostate cancer, who undergo prostate cancer screening. Therefore, PSA or %fPSA-based screening or early detection efforts do not require an adjustment for BMI.
AB - OBJECTIVES: Body mass index (BMI) may alter serum prostate specific antigen (PSA) and percent free PSA (%fPSA) and may mask the risk of prostate cancer. We investigated the relationship between BMI and PSA or %fPSA. MATERIALS AND METHODS: Height, weight, PSA and %fPSA were assessed in 616 consecutive screened men without prostate cancer. Continuously coded and categorised BMI was studied. Statistical analyses consisted of ANOVA, linear regression, bivariate and partial correlations. RESULTS: Median age was 57 years. Median PSA was 1.0 and median %fPSA was 26. Median BMI was 25.8 kg/m(2). Neither continuously coded nor categorised BMI correlated with either PSA or %fPSA in unadjusted or age-adjusted analyses (all p values > or = 0.3). CONCLUSIONS: Body mass index does not affect PSA or %fPSA in men without known prostate cancer, who undergo prostate cancer screening. Therefore, PSA or %fPSA-based screening or early detection efforts do not require an adjustment for BMI.
M3 - SCORING: Zeitschriftenaufsatz
VL - 43
SP - 1180
EP - 1187
JO - EUR J CANCER
JF - EUR J CANCER
SN - 0959-8049
IS - 7
M1 - 7
ER -