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Body mass index does not improve the ability to predict biochemical recurrence after radical prostatectomy.

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Body mass index does not improve the ability to predict biochemical recurrence after radical prostatectomy. / Chun, Felix; Briganti, Alberto; Graefen, Markus; Erbersdobler, Andreas; Walz, Jochen; Schlomm, Thorsten; Meschke, Mirja; Haese, Alexander; Valiquette, Luc; Huland, Hartwig; Karakiewicz, Pierre I.

in: EUR J CANCER, Jahrgang 43, Nr. 2, 2, 2007, S. 375-382.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Chun, F, Briganti, A, Graefen, M, Erbersdobler, A, Walz, J, Schlomm, T, Meschke, M, Haese, A, Valiquette, L, Huland, H & Karakiewicz, PI 2007, 'Body mass index does not improve the ability to predict biochemical recurrence after radical prostatectomy.', EUR J CANCER, Jg. 43, Nr. 2, 2, S. 375-382. <http://www.ncbi.nlm.nih.gov/pubmed/17141497?dopt=Citation>

APA

Chun, F., Briganti, A., Graefen, M., Erbersdobler, A., Walz, J., Schlomm, T., Meschke, M., Haese, A., Valiquette, L., Huland, H., & Karakiewicz, P. I. (2007). Body mass index does not improve the ability to predict biochemical recurrence after radical prostatectomy. EUR J CANCER, 43(2), 375-382. [2]. http://www.ncbi.nlm.nih.gov/pubmed/17141497?dopt=Citation

Vancouver

Chun F, Briganti A, Graefen M, Erbersdobler A, Walz J, Schlomm T et al. Body mass index does not improve the ability to predict biochemical recurrence after radical prostatectomy. EUR J CANCER. 2007;43(2):375-382. 2.

Bibtex

@article{8a1a99e159c54cceb21d235f5fbf3fed,
title = "Body mass index does not improve the ability to predict biochemical recurrence after radical prostatectomy.",
abstract = "PURPOSE: To test whether body mass index (BMI) improves pre- or post-operative biochemical recurrence (BCR) predictions after radical prostatectomy. MATERIALS AND METHODS: Pre- and post-operative data were available in 2416 and 2499 men, respectively. Cox regression models addressed the association between BMI and the rate of BCR after adjusting for pre- and post-operative predictors. Predictive accuracy was quantified using Harrell's concordance index, with and without BMI and subjected to 200 bootstraps to reduce overfit bias. Differences in predictive accuracy were compared using the Mantel-Haenszel test. RESULTS: After adjusting for either pre- or post-operative variables, increasing BMI was a statistically independent risk factor of BCR in both models (both p0.003). Its addition to pre- and post-operative variables respectively increased predictive accuracy measures from 69.6 to 70.2% (+0.6%, p=0.7) and from 78.1 to 78.4% (+0.3%, p=0.8). CONCLUSION: Our data emphasise that despite its significance, inclusion of BMI into models, to predict BCR, does not improve their accuracy.",
author = "Felix Chun and Alberto Briganti and Markus Graefen and Andreas Erbersdobler and Jochen Walz and Thorsten Schlomm and Mirja Meschke and Alexander Haese and Luc Valiquette and Hartwig Huland and Karakiewicz, {Pierre I}",
year = "2007",
language = "Deutsch",
volume = "43",
pages = "375--382",
journal = "EUR J CANCER",
issn = "0959-8049",
publisher = "Elsevier Limited",
number = "2",

}

RIS

TY - JOUR

T1 - Body mass index does not improve the ability to predict biochemical recurrence after radical prostatectomy.

AU - Chun, Felix

AU - Briganti, Alberto

AU - Graefen, Markus

AU - Erbersdobler, Andreas

AU - Walz, Jochen

AU - Schlomm, Thorsten

AU - Meschke, Mirja

AU - Haese, Alexander

AU - Valiquette, Luc

AU - Huland, Hartwig

AU - Karakiewicz, Pierre I

PY - 2007

Y1 - 2007

N2 - PURPOSE: To test whether body mass index (BMI) improves pre- or post-operative biochemical recurrence (BCR) predictions after radical prostatectomy. MATERIALS AND METHODS: Pre- and post-operative data were available in 2416 and 2499 men, respectively. Cox regression models addressed the association between BMI and the rate of BCR after adjusting for pre- and post-operative predictors. Predictive accuracy was quantified using Harrell's concordance index, with and without BMI and subjected to 200 bootstraps to reduce overfit bias. Differences in predictive accuracy were compared using the Mantel-Haenszel test. RESULTS: After adjusting for either pre- or post-operative variables, increasing BMI was a statistically independent risk factor of BCR in both models (both p0.003). Its addition to pre- and post-operative variables respectively increased predictive accuracy measures from 69.6 to 70.2% (+0.6%, p=0.7) and from 78.1 to 78.4% (+0.3%, p=0.8). CONCLUSION: Our data emphasise that despite its significance, inclusion of BMI into models, to predict BCR, does not improve their accuracy.

AB - PURPOSE: To test whether body mass index (BMI) improves pre- or post-operative biochemical recurrence (BCR) predictions after radical prostatectomy. MATERIALS AND METHODS: Pre- and post-operative data were available in 2416 and 2499 men, respectively. Cox regression models addressed the association between BMI and the rate of BCR after adjusting for pre- and post-operative predictors. Predictive accuracy was quantified using Harrell's concordance index, with and without BMI and subjected to 200 bootstraps to reduce overfit bias. Differences in predictive accuracy were compared using the Mantel-Haenszel test. RESULTS: After adjusting for either pre- or post-operative variables, increasing BMI was a statistically independent risk factor of BCR in both models (both p0.003). Its addition to pre- and post-operative variables respectively increased predictive accuracy measures from 69.6 to 70.2% (+0.6%, p=0.7) and from 78.1 to 78.4% (+0.3%, p=0.8). CONCLUSION: Our data emphasise that despite its significance, inclusion of BMI into models, to predict BCR, does not improve their accuracy.

M3 - SCORING: Zeitschriftenaufsatz

VL - 43

SP - 375

EP - 382

JO - EUR J CANCER

JF - EUR J CANCER

SN - 0959-8049

IS - 2

M1 - 2

ER -